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PPIases accelerate the folding of proteins (By similarity). Additionally we are shipping Cwc27 Antibodies (37) and Cwc27 Proteins (7) and many more products for this protein.
CWC27 overexpression is associated with Bladder Cancer.
By whole-exome sequencing, recessive protein-truncating mutations in CWC27 were found in seven unrelated families that show a range of clinical phenotypes, including retinal degeneration, brachydactyly, craniofacial abnormalities, short stature, and neurologic defects.
The crystal structure of a relatively protease-resistant N-terminal fragment of human Cwc27 containing the cyclophilin-type peptidyl-prolyl cis-trans isomerase (show PPIL4 ELISA Kits) domain was determined at 2.0 A resolution.
Cwc27 mutant mice have significant embryonic lethality and severe phenotypes in the complete knockout mice while mice with a partial loss-of-function allele mimic the isolated retinal degeneration phenotype.
PPIases accelerate the folding of proteins (By similarity).
, peptidyl-prolyl cis-trans isomerase CWC27 homolog
, peptidyl-prolyl cis-trans isomerase SDCCAG10
, PPIase SDCCAG10
, antigen NY-CO-10
, serologically defined colon cancer antigen 10