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anti-CXXC Finger Protein 1 (CXXC1) Antibodies

Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001. Additionally we are shipping CXXC Finger Protein 1 Proteins (2) and CXXC Finger Protein 1 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXXC1 74322 Q9CWW7
CXXC1 30827 Q9P0U4
CXXC1 291440  
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Top anti-CXXC Finger Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CXXC1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Wwestern blot analysis in mouse liver tissue lysates (35ug/lane) using CpG-binding protein/CXXC1 antibody .This demonstrates the CXXC1 antibody detected the CXXC1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB CXXC1 Antibody (Center)  western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CXXC1 antibody detected the CXXC1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB CGBP pAb tested by Western blot. Detection of CGBP by Western blot analysis. Western blot analysis using CGBP pAb at a 1:1,000 dilution against 15 µg/lane of human spleen lysate. 200 μL Log in to see 1 to 2 Days
$466.67
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details

CXXC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Human , , , ,
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Rat (Rattus) ,


Top referenced anti-CXXC Finger Protein 1 Antibodies

  1. Human Polyclonal CXXC1 Primary Antibody for EIA, WB - ABIN951679 : Crowther-Swanepoel, Broderick, Di Bernardo, Dobbins, Torres, Mansouri, Ruiz-Ponte, Enjuanes, Rosenquist, Carracedo, Jurlander, Campo, Juliusson, Montserrat, Smedby, Dyer, Matutes, Dearden, Sunter, Hall, Mainou-Fowler, Jackson, Summerfield, Harris, Pettitt: Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. in Nature genetics 2010 (PubMed)
    Show all 5 references for ABIN951679

  2. Cow (Bovine) Polyclonal CXXC1 Primary Antibody for WB - ABIN2779755 : Ansari, Mishra, Mandal: Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression. in Biochimica et biophysica acta 2008 (PubMed)

  3. Cow (Bovine) Polyclonal CXXC1 Primary Antibody for WB - ABIN2780935 : Lee, Skalnik: CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against CXXC Finger Protein 1 Interaction Partners

Zebrafish CXXC Finger Protein 1 (CXXC1) interaction partners

  1. These results suggest that LWS-activating region (LAR (show PTPRF Antibodies)) regulates both LWS-1 and LWS-2 by enhancing their expression and that interaction of LAR (show PTPRF Antibodies) with the promoters is competitive between the two genes in a developmentally restricted manner.

  2. CFP1 has an important role during postgastrulation development

Mouse (Murine) CXXC Finger Protein 1 (CXXC1) interaction partners

  1. Data indicate that CXXC finger protein 1 (Cfp1) is necessary for hematopoietic stem and multi-potential progenitor cell function and for the developmental potential of differentiating hematopoietic cells.

  2. NF-kappaB (show NFKB1 Antibodies) recruitment enhanced the occupancy of the CpG island within the 14-3-3gamma (show YWHAG Antibodies) promoter by CFP1.14-3-3gamma induction in CSR (show SCARA3 Antibodies) is enabled by the CFP1-mediated H3K4me3 enrichment in the promoter, dependent on NF-kappaB (show NFKB1 Antibodies) and sustained by E2A (show TCF3 Antibodies).

  3. The results demonstrated that Cfp1 is a specificity factor that integrates multiple signals, including promoter CpG content and gene activity, to regulate genome-wide patterns of H3K4me3.

  4. a primary function of non-methylated CpG islands is to genetically influence the local chromatin modification state by interaction with Cfp1 and perhaps other CpG-binding proteins

  5. embryonic stem cells lacking Cfp1 (CXXC1(-/-)) are viable but show increased levels of global histone H3K4 methylation, suggesting that Cfp1 functions to inhibit or restrict the activity of the Setd1A (show SETD1A Antibodies) histone H3K4 methyltransferase complex.

  6. findings show that CGBP is essential for normal epigenetic modification of the genome by cytosine methylation and for cellular differentiation, consistent with the requirement for CGBP during early mammalian development

  7. expression of either the amino half of Cfp1 (amino acids 1 to 367 [Cfp1(1-367)]) or the carboxyl half of Cfp1 (Cfp1(361-656)) is sufficient to correct all of the defects observed with embryonic stem cells that lack Cfp1

Human CXXC Finger Protein 1 (CXXC1) interaction partners

  1. NF-kappaB (show NFKB1 Antibodies) recruitment enhanced the occupancy of the CpG island within the 14-3-3gamma (show YWHAG Antibodies) promoter by CFP1.14-3-3gamma induction in CSR (show MORF4 Antibodies) is enabled by the CFP1-mediated H3K4me3 enrichment in the promoter, dependent on NF-kappaB (show NFKB1 Antibodies) and sustained by E2A (show TCF3 Antibodies).

  2. The crescent (show SFRP5 Antibodies)-shaped CFP1 CXXC domain is wedged into the major groove of the CpG DNA, distorting the B-form DNA, and interacts extensively with the major groove of the DNA.

  3. CXXC finger protein 1 is a component of the mammalian Set1 (show SETD1A Antibodies) histone H3 (show HIST3H3 Antibodies)-Lys4 methyltransferase complex

  4. CXXC finger protein 1 is required for normal proliferation and differentiation of the PLB (show PLN Antibodies)-985 myeloid cell line.

  5. CGBP interacts with MLL1, MLL2 (show MLL2 Antibodies) as well as Set1 (show SETD1A Antibodies) H3-Lysine 4 (H3K4) specific methyl-transferases and plays critical roles in regulations of MLL (show MLL Antibodies) target genes.

  6. study shows endogenous DNMT1 (show DNMT1 Antibodies) & CFP1 interact in vivo; CFP1 interaction with Setd1A (show SETD1A Antibodies) or Setd1B (show SETD1B Antibodies) not required for its interaction with DNMT1 (show DNMT1 Antibodies); result indicates CFP1 intersects cytosine methylation machinery independently of its association with Setd1 complexes

  7. expression of either the amino half of Cfp1 (amino acids 1 to 367 [Cfp1(1-367)]) or the carboxyl half of Cfp1 (Cfp1(361-656)) is sufficient to correct all of the defects observed with embryonic stem cells that lack Cfp1

CXXC Finger Protein 1 (CXXC1) Antigen Profile

Protein Summary

Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001

Gene names and symbols associated with CXXC1

  • cpg binding protein (AaeL_AAEL011688) antibody
  • CXXC finger protein 1 (CXXC1) antibody
  • CXXC finger 1 (PHD domain) (cxxc1) antibody
  • CXXC finger 1 (PHD domain) (Cxxc1) antibody
  • CXXC finger protein 1 (Cxxc1) antibody
  • CXXC finger protein 1 (cxxc1) antibody
  • 2410002I16Rik antibody
  • 5830420C16Rik antibody
  • AI426635 antibody
  • CFP1 antibody
  • CGBP antibody
  • hCGBP antibody
  • HsT2645 antibody
  • LWS-2 antibody
  • opn1lw2 antibody
  • PCCX1 antibody
  • PHF18 antibody
  • SPP1 antibody
  • ZCGPC1 antibody
  • zgc:55527 antibody

Protein level used designations for CXXC1

cpg binding protein , CXXC finger protein 1 , cpG-binding protein-like , CXXC finger 1 (PHD domain) , cfp1 , CXXC-type zinc finger protein 1 , CpG binding protein , PHD finger and CXXC domain-containing protein 1 , cpG-binding protein , DNA-binding protein with PHD finger and CXXC domain , zinc finger, CpG binding-type containing 1

GENE ID SPECIES
5575222 Aedes aegypti
100477184 Ailuropoda melanoleuca
100522911 Sus scrofa
100595741 Nomascus leucogenys
360150 Danio rerio
74322 Mus musculus
30827 Homo sapiens
480217 Canis lupus familiaris
511446 Bos taurus
291440 Rattus norvegicus
443834 Xenopus laevis
Selected quality suppliers for anti-CXXC Finger Protein 1 (CXXC1) Antibodies
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