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May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Additionally we are shipping CXXC Finger Protein 5 Proteins (7) and many more products for this protein.
Showing 10 out of 31 products:
Human Polyclonal CXXC5 Primary Antibody for EIA, WB - ABIN783347
Andersson, Södersten, Duckworth, Cascante, Fritz, Sacchetti, Cervenka, Bryja, Hermanson: CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. in The Journal of biological chemistry 2009
The finding of this study indicate that the regulation of myelin genes expression by CXXC5 is important for forming myelin structure involved with axonal electrical signal transfer in the corpus callosum.
The Dishevelled (show DVL2 Antibodies)-binding protein CXXC5 negatively regulates cutaneous wound healing.
CXXC5 is a transcriptional activator for Flk-1, mediating BMP signaling for differentiation and migration of endothelial cell and vessel formation.
High CXXC5 expression seems to affect several steps in human leukemogenesis, including intracellular events as well as extracellular communication.
Findings suggest that overexpression of CXXC5 in C2C12 myoblasts facilitated myocyte differentiation, while RNAi interference of CXXC5 significantly inhibited the differentiation of C2C12 myoblasts.
Low CXXC5 expression is associated with acute myeloid leukemia (show BCL11A Antibodies).
targeting of CXXC5/RINF should be considered as a possible therapeutic strategy, especially in high-risk patients who show increased expression in AML (show RUNX1 Antibodies) cells compared with normal hematopoietic cells
Lack of promoter hypermethylation or somatic mutations are found in the potential tumor suppressor CXXC5 in myelodysplastic syndromes or acute myeloid leukemia (show BCL11A Antibodies) with deletion 5q.
RINF overexpression represents an independent molecular marker for poor prognosis in breast tumors.
RINF expression correlates with retinoid-induced differentiation of leukemic cells and with cytokine-induced myelopoiesis of normal CD34 (show CD34 Antibodies)(+) progenitors.
These findings suggest that CF5 plays a crucial role in ATM (show ATM Antibodies)-p53 (show TP53 Antibodies) signaling in response to DNA damage.
May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity).
CXXC-type zinc finger protein 5
, CXXC finger 5 protein
, WT1-induced Inhibitor of Dishevelled
, putative MAPK-activating protein PM08
, putative NF-kappa-B-activating protein 102
, retinoid-inducible nuclear factor
, CXXC finger 5