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anti-Ca++-Dependent Secretion Activator 2 (CADPS2) Antibodies

CADPS2 encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Additionally we are shipping CADPS2 Kits (3) and CADPS2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CADPS2 26989 Q62717
CADPS2 93664 Q86UW7
CADPS2 320405 Q8BYR5
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Top anti-CADPS2 Antibodies at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of CAPS2 in human brain with CAPS2 antibody at 5 μg/ml. Western blot analysis of CAPS2 in human brain tissue lysate with CAPS2 antibody at (A) 0.5 and (B) 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$379.50
Details

CADPS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Human ,


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Mouse (Murine) ,


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Top referenced anti-CADPS2 Antibodies

  1. Human Polyclonal CADPS2 Primary Antibody for EIA, IHC (p) - ABIN499527 : Sadakata, Washida, Furuichi: Alternative splicing variations in mouse CAPS2: differential expression and functional properties of splicing variants. in BMC neuroscience 2007 (PubMed)
    Show all 3 references for ABIN499527

  2. Human Polyclonal CADPS2 Primary Antibody for IHC, ELISA - ABIN1001982 : Walent, Porter, Martin: A novel 145 kd brain cytosolic protein reconstitutes Ca(2+)-regulated secretion in permeable neuroendocrine cells. in Cell 1992 (PubMed)
    Show all 3 references for ABIN1001982

More Antibodies against CADPS2 Interaction Partners

Human Ca++-Dependent Secretion Activator 2 (CADPS2) interaction partners

  1. Mutation screening of 187 patients with autism spectrum disorders and 36 with intellectual disability identified a missense change of maternal origin disrupting CADPS2/D2DR (show DRD2 Antibodies) interaction.

  2. We speculate that haploinsufficiency of CADPS2 contributes to ASDs.

  3. identification, cloning, and comparative characterization of a second mammalian CAPS (show CAPS Antibodies) isoform, CAPS2 (show CAPS2 Antibodies); concluded that at the functional level, CAPS2 (show CAPS2 Antibodies) is largely redundant with CAPS1 (show CAPS Antibodies)

  4. Results from Cadps2-deficient mice and human data suggest that a disturbance in CADPS2-mediated neurotrophin release contributes to autistic-like cellular and behavioral phenotypes.

  5. CAPS (show CAPS Antibodies) proteins are involved in optimizing vesicular monoamine uptake and storage mediated by VMAT1 (show SLC18A1 Antibodies) and VMAT2 (show Slc18a2 Antibodies)

Mouse (Murine) Ca++-Dependent Secretion Activator 2 (CADPS2) interaction partners

  1. CAPS2 plays an important role in subcellular locality (axonal vs. somato (show SSTR5 Antibodies)-dendritic) of enhanced BDNF (show BDNF Antibodies) and NT-3 (show NTF3 Antibodies) release, which is indispensable for proper development of postnatal cerebellum.

  2. Data suggest that adequate levels of CAPS2 are critical for normal brain development and normal behavior; allelic changes due to copy number variation may contribute to autistic behavior.

  3. Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF (show BDNF Antibodies) and causes autistic-like behavior in mice

  4. identification, cloning, and comparative characterization of a second mammalian CAPS (show CAPS Antibodies) isoform, CAPS2; concluded that at the functional level, CAPS2 is largely redundant with CAPS1 (show CAPS Antibodies)

  5. results suggest that CAPS2 mediates the depolarization-dependent release of NT-3 (show NTF3 Antibodies) and BDNF (show BDNF Antibodies) from granule cells, leading to regulation in cell differentiation and survival during cerebellar development

  6. CADPS2-KO mice show autistic-like phenotypes. Moreover, the results show that some autistic patients have an aberrant splicing variant of CADPS2 mRNA, suggesting that a disturbance in CADPS2-mediated neurotrophin (show BDNF Antibodies) release contributes to autism.

  7. CADPS2/CAPS2-knockout mice exhibit pronounced impairments in cerebellar development and functions. These results are also suggestive of an involvement of the CADPS2/CAPS2 gene, which is located within the AUTS1, in the cerebellar deficits of autism.

  8. The results show the immunohistochemical localization of the CAPS (show CAPS Antibodies) family proteins in various mouse tissues.

  9. The two CAPS (show CAPS Antibodies) family proteins are complementarily distributed throughout the various brain regions of mice.

CADPS2 Antigen Profile

Protein Summary

This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CADPS2

  • Ca++-dependent secretion activator 2 (CADPS2) antibody
  • Ca++-dependent secretion activator (Cadps) antibody
  • Ca++-dependent secretion activator 2 (Cadps2) antibody
  • Ca2+-dependent activator protein for secretion 2 (Cadps2) antibody
  • A230044C21Rik antibody
  • Caps antibody
  • Caps-2 antibody
  • Caps1 antibody
  • Caps2 antibody
  • Cpd2 antibody
  • RGD1559440 antibody

Protein level used designations for CADPS2

Ca2+-dependent activator protein for secretion 2 , Ca++-dependent secretion activator 2 , CAPS-1 , Ca2+-dependent activator protein , Ca2+-dependent secretion activator , Ca<2+-dependent activator protein for secretion , calcium-dependent activator protein for secretion 1 , calcium-dependent secretion activator 1 , rCAPS , CAPS-2 , calcium-dependent activator protein for secretion 2 , calcium-dependent secretion activator 2 , cerebellum postnatal development associated protein 2

GENE ID SPECIES
100056300 Equus caballus
472494 Pan troglodytes
26989 Rattus norvegicus
93664 Homo sapiens
312166 Rattus norvegicus
475304 Canis lupus familiaris
100525671 Sus scrofa
519444 Bos taurus
320405 Mus musculus
Selected quality suppliers for anti-CADPS2 (CADPS2) Antibodies
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