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The protein encoded by CELSR2 is a member of the flamingo subfamily, part of the cadherin superfamily. Additionally we are shipping CELSR2 Kits (8) and CELSR2 Proteins (6) and many more products for this protein.
Showing 10 out of 55 products:
Cow (Bovine) Polyclonal CELSR2 Primary Antibody for IHC (p) - ABIN270746
Sugimura, He, Venkatraman, Arai, Box, Semerad, Haug, Peng, Zhong, Suda, Li: Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche. in Cell 2012
we report bi-allelic mutations in CELSR2 in a Joubert patient with cortical heterotopia, microophthalmia, and growth hormone deficiency.
no association was found between the SNPs of rs599839, rs464218 and rs6698843 at the CELSR2-PSRC1 (show PSRC1 Antibodies)-SORT1 (show SORT1 Antibodies) and the risk of coronary artery disease or ischemic stroke
CELSR2 in the cholesterol gene cluster shows a significant association with coronary artery disease and its single nucleotide polymorphism regulates plasma cholesterol levels.
The novel CAD (show CAD Antibodies)-associated locus in the vicinity of the PSRC1 (show PSRC1 Antibodies) and CELSR2 genes on chromosome 1 probably enhances CAD (show CAD Antibodies) risk through an effect on plasma LDL cholesterol.
The first signal, controlled by cadherin, EGF (show EGF Antibodies)-like, laminin G-like, seven-pass, G-type receptor (Celsr) 2, Celsr3 (show CELSR3 Antibodies), Frizzled3 (Fzd3 (show FZD3 Antibodies)) and Van Gogh (show VANGL2 Antibodies) like2 (Vangl2 (show VANGL2 Antibodies)) organizes multicilia in individual cells (single-cell polarity)
Celsr2-3 and Fzd3 (show FZD3 Antibodies) regulate axonal navigation in the forebrain by using mechanisms different from classical epithelial core planar cell polarity, and require interacting partners other than Vangl1 (show Vangl1 Antibodies)-2 that remain to be identified.
Study shows Flamingo (Fmi) and Frizzled (Fz) 8, members of noncanonical Wnt signaling, both express in and functionally maintain quiescent long-term hematopoietic stem cells.
Celsr2 and Celsr3 (show CELSR3 Antibodies) control the development and function of ependymal cilia; findings suggest that planar cell polarity signaling is involved in ependymal cilia development and in the pathophysiology of hydrocephalus, and possibly other ciliopathies
Developmental expression profiles of Celsr (Flamingo) genes in the mouse
Differential expression of the seven-pass transmembrane cadherin genes Celsr1 (show CELSR1 Antibodies)-3 and distribution of the Celsr2 protein during mouse development
Upregulation of Flamingo1/Celsr2 gene expression in both early and chronic phases of enlargement in the granule cells of the hypertrophic dentate gyrus may correlate mouse Flamingo1/Celsr2 to the development of hippocampal sclerosis.
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins\; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
EGF-like protein 2
, EGF-like-domain, multiple 2
, cadherin EGF LAG seven-pass G-type receptor 2
, cadherin family member 10
, cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
, epidermal growth factor-like 2
, epidermal growth factor-like protein 2
, flamingo homolog 3
, multiple EGF-like domains protein 3
, multiple epidermal growth factor-like domains 3
, multiple epidermal growth factor-like domains protein 3
, cadherin EGF LAG seven-pas G-type receptor 2
, flamingo-like protein celsr2
, seven-pass transmembrane cadherin
, flamingo homolog