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anti-Cadherin-Like 23 (CDH23) Antibodies

CDH23 is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins.

list all antibodies Gene Name GeneID UniProt
CDH23 64072 Q9H251
CDH23    
CDH23    
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Top anti-CDH23 Antibodies at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA Anti-CDH23 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959291 dilution 1:100. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Cadherin 23 staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cadherin 23 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ICC   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Rabbit Un-conjugated IHC   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, WB   100 μL Log in to see 9 to 14 Days
$354.05
Details
Human Rabbit Un-conjugated IHC (p), IHC, ELISA   50 μg Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated   50 μL Log in to see 9 to 14 Days
$417.00
Details

CDH23 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
,

Mouse (Murine)


Rat (Rattus)


More Antibodies against CDH23 Interaction Partners

Human Cadherin-Like 23 (CDH23) interaction partners

  1. Four (3.1 %) of 128 children carried two CDH23 mutant alleles, and SLC26A4 (show SLC26A4 Antibodies) and GJB2 (show GJB2 Antibodies) accounted for 18.0 and 17.2 %, respectively and showed profound nonsyndromic sensorineural hearing loss with minimal residual hearing.

  2. The results revealed that CDH23 mutations are highly prevalent in patients with congenital high-frequency sporadic or recessively inherited hearing loss

  3. Description of the spectrum of mutations in CDH23 in 374 families with autosomal recessive, non-syndromic hearing loss from India.

  4. The results of this study confirm that CDH23 genetic variant may modify the susceptibility to noise-induced hearing loss development in humans

  5. mutations in the CDH23 gene are one of the most important causes of non-syndromic hearing loss in East Asians.

  6. Hearing loss was found to co-segregate with locus-specific STR (show STATH Antibodies) markers for CDH23 in 1 Pakistani family.

  7. mutations of the CDH23 gene are an important cause of non-syndromic hearing loss.

  8. Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin (show USH1C Antibodies) suggest a stable anchorage structure at the tip link of stereocilia

  9. Despite that the Ahl allele of Cdh23 had been implicated with ARHI in mice, we found no positive association of the CDH23 tag SNP in intron 7 with ARHI in Han Chinese.

  10. cadherin-23 is up-regulated in breast cancer tissue versus normal tissue and we propose that cadherin-23-mediated heterotypic adhesion between invading tumor cells and stromal fibroblasts may play a role in the metastatic cascade.

Zebrafish Cadherin-Like 23 (CDH23) interaction partners

  1. Unlike other vertebrates, cdh23 is not detectable in zebrafish photoreceptors but instead expressed by a small subset of GABAergic amacrine cells.

  2. Cdh23 is an essential tip link component required for hair-cell mechanotransduction

CDH23 Antigen Profile

Protein Summary

This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.

Gene names and symbols associated with CDH23

  • cadherin-related 23 (CDH23) antibody
  • cadherin-like 23 (cdh23) antibody
  • cadherin-like 23 (CDH23) antibody
  • cadherin-like 23 (LOC100337921) antibody
  • CDH23 antibody
  • CDHR23 antibody
  • USH1D antibody

Protein level used designations for CDH23

cadherin-23 , cadherin-like 23 , cadherin-related family member 23 , otocadherin , cadherin 23 , cadherin related 23 , spu , sputnik , ush1d

GENE ID SPECIES
64072 Homo sapiens
407978 Danio rerio
423718 Gallus gallus
450516 Pan troglodytes
784716 Bos taurus
100337921 Oryctolagus cuniculus
Selected quality suppliers for anti-CDH23 (CDH23) Antibodies
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