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Calcium Binding tyrosine-(Y)-phosphorylation Regulated Proteins (CABYR)

To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. Additionally we are shipping Calcium Binding tyrosine-(Y)-phosphorylation Regulated Antibodies (18) and Calcium Binding tyrosine-(Y)-phosphorylation Regulated Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CABYR CABYR 686189  
CABYR 26256 O75952
CABYR 71132 Q9D424
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Top Calcium Binding tyrosine-(Y)-phosphorylation Regulated Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,377.00
Details
Yeast Fox His tag   1 mg Log in to see 56 to 66 Days
$3,411.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CABYR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Calcium Binding tyrosine-(Y)-phosphorylation Regulated (CABYR) Interaction Partners

Human Calcium Binding tyrosine-(Y)-phosphorylation Regulated (CABYR) interaction partners

  1. Short hairpin RNA-mediated knockdown of CABYR-a/b significantly inhibited the proliferation of NCI-H460 and A549 cells and resulted in the attenuation of Akt (show AKT1 Proteins) phosphorylation, which is constitutively active in lung cancer cells.

  2. CABYR-c is highly expressed in hepatocellular carcinoma tissues and may play an oncogenic role in heptocarcinogenesis as well as its progression.

  3. CABYR variants form a complex not only with the scaffolding protein AKAP3 but also with another RII-like domain-containing protein in the sperm fibrous sheath.

  4. High CABYR is associated with neoplasms.

  5. The expression of NF-kappaB (show NFKB1 Proteins) was not significantly affected by silencing CABYR in 293T cells.

  6. Northern blot showed that CABYR transcripts were expressed more distinctly in the fetal brain than in the adult brain, suggesting that this protein may play a role during brain development.

  7. splice variants containing CR-B are expressed during spermiogenesis and assemble into the fibrous sheath of the principal piece; however, calcium binding occurs only to those CABYR isoforms containing CABYR-A

Mouse (Murine) Calcium Binding tyrosine-(Y)-phosphorylation Regulated (CABYR) interaction partners

  1. CABYR expresses at the late stage of spermiogenesis and its isoforms oligomerize and bind with AKAPs and ropporin; which suggests that CABYR participates in the assembly of the fibrous sheath.

Calcium Binding tyrosine-(Y)-phosphorylation Regulated (CABYR) Protein Profile

Protein Summary

To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Transcript variants of this gene encode multiple protein isoforms. An additional transcript and isoform has not been fully characterized.

Gene names and symbols associated with CABYR

  • calcium binding tyrosine-(Y)-phosphorylation regulated (Cabyr)
  • calcium binding tyrosine-(Y)-phosphorylation regulated (CABYR)
  • calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) (Cabyr)
  • 1700016C01Rik protein
  • 4933421A18Rik protein
  • CABYRa protein
  • CABYRc protein
  • CABYRc/d protein
  • CABYRe protein
  • CBP86 protein
  • CT88 protein
  • FSP-2 protein
  • FSP2 protein

Protein level used designations for CABYR

calcium-binding tyrosine-phosphorylation regulated protein , calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) , calcium-binding protein 86 , calcium-binding tyrosine phosphorylation-regulated protein , calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) , cancer/testis antigen 88 , fibrousheathin 2 , fibrousheathin II , fibrousheathin-2 , testis-specific calcium-binding protein CBP86

GENE ID SPECIES
686189 Rattus norvegicus
26256 Homo sapiens
71132 Mus musculus
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