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Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit Proteins (CACNA1I)

CACNA1I encodes the pore-forming alpha subunit of a voltage gated calcium channel. Additionally we are shipping CACNA1I Antibodies (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse CACNA1I CACNA1I 239556  
CACNA1I 8911 Q9P0X4
Rat CACNA1I CACNA1I 56827 Q9Z0Y8
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Top CACNA1I Proteins at antibodies-online.com

Showing 2 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CACNA1I Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I) Interaction Partners

Mouse (Murine) Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I) interaction partners

  1. Extracellular pressure increases [Ca(2 (show CA2 Proteins)+)]i via Cav3.3, driving a PKC-beta (show PRKCB Proteins)- IKK (show CHUK Proteins)- IkB (show NFKBIB Proteins)-NF-kB pathway that stimulates cancer cell proliferation

  2. using Ca(V)3.3(-/-) mice we found that Ca(V)3.3 channels trigger synaptic plasticity in reticular thalamic neurons

  3. data identify a central role for Ca(V)3.3 channels in the rhythmogenic properties of the sleep-spindle generator and provide a molecular target to elucidate the roles of sleep spindles for brain function and development.

Human Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I) interaction partners

  1. Extracellular pressure increases [Ca(2 (show CA2 Proteins)+)]i via Cav3.3, driving a PKC-beta (show PRKCB Proteins)- IKK (show CHUK Proteins)- IkB (show NFKBIB Proteins)-NF-kB pathway that stimulates cancer cell proliferation

  2. Ethanol primarily affects the CaV3.2 isoform of T-type Ca(2)+ channels, acting through protein kinase C.

  3. Specific contribution of human T-type calcium channel isotypes (alpha(1G (show CACNA1G Proteins)), alpha(1H) and alpha(1I)) to neuronal excitability.

  4. intracellular regions after repeats I and IV play a role in gating interdependently, suggesting a direct interaction, and splice variation of Cav3.3 channels provides a mechanism for fine-tuning latency and duration of low-threshold spikes.

  5. CatSper1 (show CATSPER1 Proteins) and CatSper2 (show CATSPER2 Proteins) can associate with and modulate the function of the Ca(v)3.3 channel, which might be important in the regulation of sperm function.

  6. two distinct regions of the Cav3.3 channel are necessary and sufficient for complete M1 receptor-mediated channel inhibition

  7. The sodium channel toxins tetrodotoxin and saxitoxin interact with the alpha-subunit (show POLG Proteins) of T-type Ca 2 (show CA2 Proteins)+ channels.

CACNA1I Protein Profile

Protein Summary

This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with CACNA1I

  • calcium channel, voltage-dependent, T type, alpha 1I subunit (CACNA1I)
  • calcium channel, voltage-dependent, T type, alpha 1I subunit (cacna1i)
  • calcium channel, voltage-dependent, alpha 1I subunit (Cacna1i)
  • calcium channel, voltage-dependent, T type, alpha 1I subunit (Cacna1i)
  • Ca(v)3.3 protein
  • CACNA1L protein
  • Cav3.3 protein
  • si:ch211-51h13.1 protein

Protein level used designations for CACNA1I

alpha1I T-type calcium channel subunit , calcium channel, voltage-dependent, T type, alpha 1I subunit , voltage-dependent T-type calcium channel alpha-1I subunit , voltage-dependent T-type calcium channel subunit alpha-1I-like , low voltage-activated T-type calcium channel alpha-1 subunit (CACNA1I) , low-voltage-activated calcium channel alpha13.3 , calcium channel, voltage-dependent, alpha 1I subunit , voltage-dependent T-type calcium channel subunit alpha-1I , voltage-gated calcium channel subunit alpha Cav3.3 , caVT.3 , hypothetical gene supported by NM_020084 , voltage-dependent calcium channel

GENE ID SPECIES
282413 Bos taurus
427900 Gallus gallus
458848 Pan troglodytes
708146 Macaca mulatta
100432497 Pongo abelii
100555412 Anolis carolinensis
100587399 Nomascus leucogenys
239556 Mus musculus
8911 Homo sapiens
56827 Rattus norvegicus
566351 Danio rerio
481243 Canis lupus familiaris
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