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anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Antibodies

CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Additionally we are shipping Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Proteins (9) and Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CACNA1C 775 Q13936
CACNA1C 12288 Q01815
CACNA1C 24239 P22002
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Top anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Antibodies at antibodies-online.com

Showing 10 out of 185 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Hamster Mouse Un-conjugated ICC, IF, IP, IHC, WB Cav1 2(S57-46) IP from INS-1E cells stained with anti-Cav1.2 poly Cav1.2 (S57-46), Mouse brain tissue, Amplifier 100 μg Log in to see 3 to 4 Days
$383.90
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of rat brain membranes: 1. Anti-CaV1.2 antibody, (1:200). 2. Anti-CaV1.2 antibody, preincubated with the control peptide antigen. Expression of Cav1.2 in mouse cerebellum Immunohistochemical staining of mouse cerebellum with Anti-Cav1.2 antibody. A. Cav1.2 (red) appears in Purkinje cells (horizontal arrows) and is distributed diffusely in the molecular layer (Mol) including in Purkinje dendrites (vertical arrows). B. Staining of Purkinje nerve cells with mouse anti-Calbindin 28K (green) demonstrates the location of dendrites in the molecular layer. C. Merged image of panels A and B. 50 μL Log in to see 10 to 11 Days
$678.57
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Rabbit Mouse Un-conjugated ICC, IP, IHC, WB 100 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Goat Un-conjugated ELISA, WB EB08821 (0.5µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p) Anti-CACNA1C / Cav1.2 antibody  ABIN1048367 IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-CACNA1C / Cav1.2 antibody  ABIN1048368 IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of Cav1.2 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, IP, WB   0.2 mL Log in to see 6 to 8 Days
$533.50
Details

CACNA1C Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Antibodies

  1. Hamster Monoclonal CACNA1C Primary Antibody for ICC, IF - ABIN361759 : Krey, Moussay, Thiel, Ruemenapf: Role of the low-density lipoprotein receptor in entry of bovine viral diarrhea virus. in Journal of virology 2006 (PubMed)
    Show all 3 references for ABIN361759

  2. Human Polyclonal CACNA1C Primary Antibody for EIA, IP - ABIN1105621 : Lemke, Welling, Christel, Blaich, Bernhard, Lenhardt, Hofmann, Moosmang: Unchanged beta-adrenergic stimulation of cardiac L-type calcium channels in Ca v 1.2 phosphorylation site S1928A mutant mice. in The Journal of biological chemistry 2008 (PubMed)

  3. Human Polyclonal CACNA1C Primary Antibody for EIA, WB - ABIN375180 : Saud, Minobe, Wang, Han, Horiuchi, Hao, Kameyama: Calpastatin binds to a calmodulin-binding site of cardiac Cav1.2 Ca2+ channels. in Biochemical and biophysical research communications 2007 (PubMed)

  4. Human Polyclonal CACNA1C Primary Antibody for IHC, WB - ABIN1742110 : Kreuzberg, Theissen, Schicha, Schröder, Mehlhorn, de Vivie, Bokník, Neumann, Grohé, Herzig: Single-channel activity and expression of atrial L-type Ca(2+) channels in patients with latent hyperthyroidism. in American journal of physiology. Heart and circulatory physiology 2000 (PubMed)

More Antibodies against Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Interaction Partners

Xenopus laevis Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. Competitive and non-competitive regulation of calcium-dependent inactivation in CaV1.2 L-type Ca2 (show CA2 Antibodies)+ channels by calmodulin (show Calm2 Antibodies) and Ca2 (show CA2 Antibodies)+-binding protein 1.

Rabbit Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. a direct physical interaction between the N terminus (NT) and C terminus (CT) of the main subunit of the L-type Ca(2 (show CA2 Antibodies)+) channel CaV1.2, alpha1C, is reported.

  2. These results reveal a new dimension of regulation of Ca(V)1.2 channels through phosphorylation of the Hook domains of their beta subunits.

  3. These findings suggest that N-glycosylation contributes to the surface expression and voltage-dependent gating of Cav1.2.

  4. Data show that cardiac L-type calcium (CaV1.2) channels form clusters that undergo dynamic, reciprocal, allosteric interactions.

  5. these findings provide evidence for a new role of Homer1 (show HOMER1 Antibodies) supporting the regulation of Cav1.2 channels by STIM1 (show STIM1 Antibodies).

  6. structural flexibility of CaV1.2 and CaV2.2 (show CACNA1B Antibodies) I-II proximal linker

  7. These results suggest a complex antagonistic interplay between G(q)-activated PKC and Gbetagamma in regulation of L-VDCC, in which multiple cytosolic segments of alpha(1C) are involved.

  8. There were substantial transmural gradients in Cav1.2, KChIP2 (show KCNIP2 Antibodies), ERG (show KCNH2 Antibodies), KvLQT1 (show KCNQ1 Antibodies), Kir2.1 (show KCNJ2 Antibodies), NCX1 (show SLC8A1 Antibodies), SERCA2a (show ATP2A2 Antibodies) and RyR2 (show RYR2 Antibodies) at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

  9. Ca v1.2 binding site for PP2A and PP2B

  10. Swapping the I-II intracellular linker between L-type CaV1.2 and R-type CaV2.3 (show CACNA1E Antibodies) high-voltage gated calcium channels exchanges activation attributes.

Human Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. Copy number increase of CACNA1C are associated with esophageal squamous cell carcinoma.

  2. CACNA1C modulates the cellular rhythm amplitude response to lithium, providing a specific link between LTCCs and circadian rhythms in the context of Bipolar disorder and lithium

  3. Findings indicate that CACNA1C-related differences in amygdala structure and function are present by adolescence.

  4. The associations of CACNA1C rs10774035 with outcome in schizophrenia-spectrum and non-association with outcome in bipolar disorders

  5. Single nucleotide polymorphism in an intron of the CACNA1C gene conveyed an increased risk for developing Bipolar disorder.

  6. CACNA1C risk variant affects facial emotion recognition in healthy individuals.

  7. This integrative genomic study confirmed the role of RUNX2 (show RUNX2 Antibodies) as a potential driver of AS and identified a new AS susceptibility gene, CACNA1C, belonging to the calcium signaling pathway.

  8. Study suggests initial support for a link between bipolar disorder risk SNPs rs472913 (1p32.1) and rs1006737 (CACNA1C) and brain arousal regulation

  9. we investigated the association of CACNA1C and ANK3 (show ANK3 Antibodies) with SZ using meta-analytic techniques.

  10. Meta-analysis associated CACNA1C single nucleotide polymorphisms with schizophrenia family samples

Mouse (Murine) Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. Results provide evidence that decreased Cacna1c expression has a protective role in the modulation of age-related cognitive declines, and support an interaction between Cacna1c, sex and memory impairment

  2. Both the extracellular PFXYD motif and the transmembrane domain of PLM (show FXYD1 Antibodies) but not the cytoplasmic tail were necessary for regulation of peak L-type Ca(2 (show CA2 Antibodies)+) current amplitude.

  3. Treatment of MSC (show MSC Antibodies) with BMP4 (show BMP4 Antibodies) caused a significant increase in expression of Cav1.2, a delay in expression of Cav1.1 (show CACNA1S Antibodies), and a reduction in the duration of calcium transients when extracellular calcium was removed

  4. data suggest that miR (show MLXIP Antibodies)-103 inhibits osteoblast proliferation mainly through suppression of Cav1.2 expression under simulated microgravity condition

  5. The down-regulation of Cav1.2 expression and the inhibition of LTCCs caused by mechanical unloading in osteoblasts are partially due to miR (show MLXIP Antibodies)-103 up-regulation.

  6. Ammonium-induced deregulation of astroglial Ca(2 (show CA2 Antibodies)+) signalling, is, in part, associated with upregulation of Cav1.2 L-type calcium channels

  7. Methamphetamine alters DNA methylation (show HELLS Antibodies), expression, and protein abundance of CACNA1C.

  8. demonstrate for the first time that both Cav1.2 and Cav1.3 (show CACNA1D Antibodies) are necessary for neuronal survival but are differentially required for the biophysical properties of neurons

  9. Our findings reveal that the intra-SR protein (show RNPS1 Antibodies) Casq2 (show CASQ2 Antibodies) is largely responsible for the phenomenon of SR Ca(2 (show CA2 Antibodies)+) release refractoriness in murine ventricular myocytes.

  10. results suggest the involvement of Cacna1c (Cav1.2) in fast electroencephalogram oscillations and REM (show REM1 Antibodies) sleep regulatory processes

Cow (Bovine) Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. These results suggest that structural rearrangements of CaV1.2 generated through the binding of BayK8644 or FPL64176, by altering the channel activity, could affect depolarization-evoked catecholamine secretion prior to cation transport.

  2. CaV3.1 (show CACNA1G Antibodies) structural analysis and comparison to CaV1.2 channel

Guinea Pig Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. These results suggest that PKA and phosphatase(s) attached on or near the Ca(V)1.2 channel regulate the basal channel activity, presumably through modulation of the dynamic CaM (show CALM Antibodies) interaction with the channel.

  2. CaM (show CALM Antibodies) may tether to the channel with its single lobe, leading to multiple CaM (show CALM Antibodies) molecule binding to increase the grade of Ca(2 (show CA2 Antibodies)+)-dependent regulation of Cav1.2

Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Antigen Profile

Protein Summary

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.

Gene names and symbols associated with CACNA1C

  • calcium channel, voltage-dependent, L type, alpha 1C subunit (cacna1c) antibody
  • calcium channel, voltage-dependent, L type, alpha 1C subunit (CACNA1C) antibody
  • calcium channel (CACB) antibody
  • calcium channel, voltage-dependent, L type, alpha 1C subunit (Cacna1c) antibody
  • cardiac L-type calcium channel (CACH2C) antibody
  • Red blood cell count (RBC) antibody
  • C-LTCC antibody
  • ca(v)1.2 antibody
  • CACH2 antibody
  • CACH2C antibody
  • CACN2 antibody
  • Cacna1c antibody
  • CACNL1A1 antibody
  • CAV1.2 antibody
  • Cchl1a1 antibody
  • CHCACHA1C antibody
  • ICA antibody
  • isl antibody
  • LQT8 antibody
  • MBC antibody
  • MELC-CC antibody
  • RATIVS302 antibody
  • TS antibody

Protein level used designations for CACNA1C

ZfCav1.2 , island beat , voltage-dependent L-type calcium channel subunit alpha-1C , L-type Ca channel alpha 1 subunit , L-type calcium channel CaV1.2 , atrium L-type calcium channel , calcium channel, voltage-dependent, L type, alpha 1C subunit , voltage-dependent L-type calcium channel subunit alpha-1C-like , calcium channel voltage-dependent L type Cav1.2, alpha 1c subunit , CaCB receptor , smooth muscle calcium channel blocker , DHPR, alpha-1 subunit , calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle , calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit , voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10* , L-type Cav1.2 , brain class C , calcium channel voltage-dependent alpha1c subunit , neuronal voltage-gated calcium channel alpha 1C subunit , skeletal muscle-specific calcium channel , voltage-gated calcium channel subunit alpha Cav1.2 , L-type calcium channel alpha-1 subunit , RBC , calcium channel, voltage-dependent, alpha 1C subunit , voltage-gated calcium channel alpha 1C subunit , L-type voltage-gated calcium channel alpha1C subunit ChCaChA1C , L-type voltage-dependent calcium channel alpha-1 subunit , cardiac L-type calcium channel , Voltage-dependent L-type calcium channel subunit alpha-1C

GENE ID SPECIES
170581 Danio rerio
403516 Canis lupus familiaris
100442085 Pongo abelii
100462911 Xenopus laevis
100101555 Oryctolagus cuniculus
775 Homo sapiens
12288 Mus musculus
24239 Rattus norvegicus
408015 Bos taurus
395891 Gallus gallus
100135490 Cavia porcellus
100144322 Oryctolagus cuniculus
101180626 Sus scrofa
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