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anti-Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B) Antibodies

The protein encoded by CACNA1B is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. Additionally we are shipping CACNA1B Kits (10) and CACNA1B Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CACNA1B 774 Q00975
CACNA1B 12287 O55017
CACNA1B 257648  
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Top anti-CACNA1B Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IHC, WB Western blot analysis of rat brain membranes: 1. Anti-CaV2.2 antibody, (1:200). 2. Anti-CaV2.2 antibody, preincubated with the control antigen. Expression of Cav2.2 in mouse cerebellum Immunohistochemical staining of mouse cerebellum with Anti-Cav2.2 antibody, (1:100). A. Cav2.2 (red) appears in Purkinje cells (arrows) and is distributed diffusely in the molecular layer (Mol). B. Staining of Purkinje cells with mouse anti-Calbindin 28K (green) demonstrates the restriction of Cav2.2 to cell bodies but not to dendrites in the molecular layer. C. Merged image of panels A and B. 25 μL Log in to see 10 to 11 Days
$535.71
Details
Human Rabbit Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of methanol-fixed A549, using CACNA1B, antibody at 1:500 dilution. WB Image CACNA1B antibody [C3], C-term detects CACNA1B protein by Western blot analysis. A. 30 µg U87-MG whole cell lysate/extract 5 % SDS-PAGE CACNA1B antibody [C3], C-term , dilution: 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Mouse Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ICC, WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Un-conjugated IHC   0.1 mg Log in to see 5 to 7 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Rabbit Un-conjugated IF, WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Rat Rabbit Un-conjugated WB 50 μg Log in to see 5 to 6 Days
$398.48
Details

CACNA1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CACNA1B Antibodies

  1. Human Polyclonal CACNA1B Primary Antibody for IHC, WB - ABIN350135 : Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: DNA sequence and analysis of human chromosome 9. ... in Nature 2004 (PubMed)
    Show all 4 references for ABIN350135

  2. Human Polyclonal CACNA1B Primary Antibody for IHC - ABIN965734 : Coppola, Waldmann, Borsotto, Heurteaux, Romey, Mattéi, Lazdunski: Molecular cloning of a murine N-type calcium channel alpha 1 subunit. Evidence for isoforms, brain distribution, and chromosomal localization. in FEBS letters 1994 (PubMed)
    Show all 2 references for ABIN965734

  3. Human Polyclonal CACNA1B Primary Antibody for WB - ABIN265031 : Dubel, Starr, Hell, Ahlijanian, Enyeart, Catterall, Snutch: Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)

  4. Human Polyclonal CACNA1B Primary Antibody for ICC, IHC - ABIN1742169 : Scheuber, Miles, Poncer: Presynaptic Cav2.1 and Cav2.2 differentially influence release dynamics at hippocampal excitatory synapses. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)

More Antibodies against CACNA1B Interaction Partners

Human Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B) interaction partners

  1. These results do not support a causal association between the CACNA1B c.4166G>A; (p.R1389H) variant and M-D.

  2. the consensus motifs of S-nitrosylation were much more abundant in Cav2.2 than in Cav1.2 (show CACNA1C Antibodies) and Cav2.1 (show CACNA1A Antibodies).

  3. AP-1 (show FOSB Antibodies) binding motifs, present only in exon 37a, enhance intracellular trafficking of exon 37a-containing Ca(V)2.2 to the axons and plasma membrane of rat dorsal root ganglia neurons

  4. CACNA1B mutation is linked to unique myoclonus-dystonia syndrome.

  5. The first disease connection for Cav2.2 channels [review]

  6. The interaction between LC1 (show MAP1B Antibodies) and the N-type channel (CaV2.2 channel) was demonstrated.

  7. with membrane-localized CaV beta subunits, CaV2.2 channels are subject to Gbetagamma-mediated voltage-dependent inhibition, whereas cytosol-localized beta subunits confer more effective PIP2-mediated voltage-independent regulation

  8. new mechanistic perspectives, and reveal unexpected variations in determinants, underlying inhibition of Ca(V)1.2 (show CACNA1C Antibodies)/Ca(V)2.2 channels by distinct RGK GTPases.

  9. Ca(2 (show CA2 Antibodies)+) exits the channel through the Cav2.2.

  10. polymorphisms and haplotypes in the human CACNA1B gene show significant differences between cerebral infarction and control patients

Mouse (Murine) Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B) interaction partners

  1. Thus, GHSR1a differentially inhibits CaV2 (show CAV2 Antibodies) channels by Gi/o or Gq protein pathways depending on its mode of activation.

  2. Blockade of Cav2.2 in inflammatory arthritis leads to up-regulation of the osteoclast activator RANKL (show TNFSF11 Antibodies) and concomitant joint and bone destruction.

  3. Results identified altered synaptic transmission in the olfactory system of Cav2.2-deficient mice and suggest that the olfactory system could become an attractive model to learn more about this channel and the consequences of its removal

  4. Gaba B receptors were found to mediate Cav2.2 channel inhibition.

  5. Cav2.1 (show CACNA1A Antibodies)-2.3 have unique contributions to the dynamics at the Schaffer collateral synapse that are engaged by the complex patterns of afferent activity seen in vivo

  6. Results demonstrate that sensory neurons from Nf1 (show NF1 Antibodies)+/- mice, exhibit increased N-type (Cav2.2) ICa and likely account for the increased release of substance P (show TAC1 Antibodies) and calcitonin gene-related peptide (show CALCA Antibodies) that occurs in Nf1 (show NF1 Antibodies)+/- sensory neurons

  7. data suggest that the different roles that Ca(V)2.1 (show CACNA1A Antibodies) and Ca(V)2.2 play in MNC secretion may be a result of the different levels of expression of Ca(V)2.1 (show CACNA1A Antibodies) in VP and OT MNCs

  8. CaV2.2 and alpha2delta-1 are intimately associated at the plasma membrane

  9. These findings identify an interaction between ankyrin-B (show ANK2 Antibodies) and both Cav2.1 (show CACNA1A Antibodies) and Cav2.2 at the amino acid level that is necessary for proper Cav2.1 (show CACNA1A Antibodies) and Cav2.2 targeting in vivo.

  10. Blocking Cav2.2 channels abolishes respiratory activity in all brainstem slices from Cav2.1 (show CACNA1A Antibodies) genetically ablated animals.

Rabbit Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B) interaction partners

  1. The monomeric G proteins AGS1 (show RASD1 Antibodies) and Rhes (show RASD2 Antibodies) selectively influence Galphai-dependent signaling to modulate N-type (CaV2.2) calcium channels.

CACNA1B Antigen Profile

Protein Summary

The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CACNA1B

  • calcium channel, voltage-dependent, N type, alpha 1B subunit (CACNA1B) antibody
  • calcium channel, voltage-dependent, N type, alpha 1B subunit (Cacna1b) antibody
  • alpha(1B) antibody
  • AW050276 antibody
  • AW060892 antibody
  • AW822256 antibody
  • BIII antibody
  • CACNL1A5 antibody
  • CACNN antibody
  • Cav2.2 antibody
  • Cchn1a antibody

Protein level used designations for CACNA1B

calcium channel, voltage-dependent, L type, alpha 1B subunit , voltage-dependent N-type calcium channel subunit alpha-1B , calcium channel, voltage-dependent, N type, alpha 1B subunit , Cav2.2 voltage-gated Ca2+ channel , brain calcium channel III , calcium channel alpha12.2 subunit , calcium channel, L type, alpha-1 polypeptide , calcium channel, N type , calcium channel, voltage-dependent, alpha 1B subunit, N type , voltage-gated calcium channel alpha subunit Cav2.2 , voltage-gated calcium channel subunit alpha Cav2.2 , BIII , voltage gated N-type calcium channel Ca(v)2.2 , CHCACHA1B , N-type voltage-gated calcium channel alpha1B subunit ChCaChA1B , calcium channel BIII

GENE ID SPECIES
282410 Bos taurus
464893 Pan troglodytes
480660 Canis lupus familiaris
721452 Macaca mulatta
774 Homo sapiens
12287 Mus musculus
257648 Rattus norvegicus
374169 Gallus gallus
100008979 Oryctolagus cuniculus
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