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anti-Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) Antibodies

CACNA2D1 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Additionally we are shipping CACNA2D1 Proteins (8) and CACNA2D1 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CACNA2D1 781 P54289
CACNA2D1 12293 O08532
CACNA2D1 25399  
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Top anti-CACNA2D1 Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB Host: Rabbit  Target Name: CACNA2D1  Sample Tissue: Fetal MuscleLane A:  Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 5 µg/mL Lysate Quantity: 41 µg/lane/LaneGel Concentration:.12 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN190770 (0.03µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB AP17917PU-N CACNA2D1 Antibody (N-term) Flow Cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Western blot analysis of CACNA2D1 Antibody (N-term) in mouse brain tissue lysates (35ug/lane). CACNA2D1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of CACNA2D1 Antibody (N-term) (ABIN652644) in mouse brain tissue lysates (35 µg/lane). CACNA2D1 (arrow) was detected using the purified polyclonal antibody. CACNA2D1 Antibody (N-term) (ABIN652644) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Skeletal muscle 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Goat Un-conjugated ELISA, WB Immunohistochemistry: CACNA2D1 Antibody [ABIN253173] - ABIN253173 (0.03ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 5 to 7 Days
$427.88
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

CACNA2D1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-CACNA2D1 Antibodies

  1. Human Polyclonal CACNA2D1 Primary Antibody for WB - ABIN265035 : Kim, Kim, Lee, King, Chin: Rat brain expresses an alternatively spliced form of the dihydropyridine-sensitive L-type calcium channel alpha 2 subunit. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 3 references for ABIN265035

  2. Human Polyclonal CACNA2D1 Primary Antibody for ELISA, WB - ABIN190770 : Hullin, Matthes, von Vietinghoff, Bodi, Rubio, DSouza, Friedrich Khan, Rottländer, Hoppe, Mohacsi, Schmitteckert, Gilsbach, Bünemann, Hein, Schwartz, Herzig: Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failure. in PLoS ONE 2007 (PubMed)
    Show all 2 references for ABIN190770

  3. Human Polyclonal CACNA2D1 Primary Antibody for EIA, WB - ABIN453548 : Williams, Feldman, McCue, Brenner, Velicelebi, Ellis, Harpold: Structure and functional expression of alpha 1, alpha 2, and beta subunits of a novel human neuronal calcium channel subtype. in Neuron 1992 (PubMed)
    Show all 2 references for ABIN453548

  4. Human Polyclonal CACNA2D1 Primary Antibody for WB - ABIN374788 : Neely, Hess, Costigan, Keene, Goulas, Langeslag, Griffin, Belfer, Dai, Smith, Diatchenko, Gupta, Xia, Amann, Kreitz, Heindl-Erdmann, Wolz, Ly, Arora, Sarangi, Dan, Novatchkova, Rosenzweig, Gibson, Truong, Schramek, Zoranovic, Cronin, Angjeli, Brune, Dietz: A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. in Cell 2010 (PubMed)

  5. Chicken Polyclonal CACNA2D1 Primary Antibody for WB - ABIN2776091 : Stotz, Barr, McRory, Chen, Jarvis, Zamponi: Several structural domains contribute to the regulation of N-type calcium channel inactivation by the beta 3 subunit. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against CACNA2D1 Interaction Partners

Human Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) interaction partners

  1. detected a joint effect of SNP and G x E interaction in BMP2 (show BMP2 Antibodies) and CACNA2D1 for depressive state.

  2. All three patients present with epilepsy and intellectual disability pinpointing the CACNA2D1 gene as an interesting candidate gene for these clinical features.

  3. Compound mutation of CACNA2D1 and RANGRF (show RANGRF Antibodies) genes were found. To the best of our knowledge, this is the first comprehensive description of the concurrence of these two mutations and histiocytoid cardiomyopathy.

  4. High prevalence of CACNA2D1, SCN5A (show SCN5A Antibodies), and CACNB2 (show CACNB2 Antibodies) genetic variants in the Danish population previously associated with Brugada syndrome has been found in new exome data.

  5. Functional expression of CACNA2D1 is inhibited by prion protein (show PRNP Antibodies) expression with competition at glycosylphosphatidylinositol.

  6. this study reports the identification and characterization of the human alpha2delta-1 subunit gene promoter region and its regulation by specific transcription factor 1 (show HNF1A Antibodies).

  7. In neocortical slices from transgenic mice having a point mutation (i.e., R217A) of the alpha2delta-1 subunit of voltage-sensitive calcium channels, pregabalin does not affect potassium-evoked glutamate (show GRIN1 Antibodies) release, yet inhibits this release in wild-type mice.

  8. Results show that mutation of CACNA2D1 gene causes a new varant of SCTS (show ANO6 Antibodies).

  9. CACNA2D1 is a novel Brugada Syndrome susceptibility gene.

  10. CACNA2D1 has structural domains which contribute to the regulation of N-type calcium channel inactivation

Rabbit Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) interaction partners

  1. these findings provide evidence for a new role of Homer1 (show HOMER1 Antibodies) supporting the regulation of Cav1.2 (show CACNA1C Antibodies) channels by STIM1 (show STIM1 Antibodies).

Pig (Porcine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) interaction partners

Cow (Bovine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) interaction partners

  1. The objective of the present study was to identify polymorphisms of the CACNA2D1 gene, and to analyze associations between these polymorphisms and mastitis in several cattle breeds.

  2. CACNA2D1 gene is one of the potential candidate genes influencing carcass and meat quality traits.

Mouse (Murine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) interaction partners

  1. CaV2.2 (show CACNA1B Antibodies) and alpha2delta-1 are intimately associated at the plasma membrane

  2. These findings suggest that the alpha(2)delta(4) subunit participates in the modulation of L-type Ca(2 (show CA2 Antibodies)+) current regulating neurotransmitter release from photoreceptor terminals

  3. Expression of Cacna2d1 is enhanced in the amygdala in a model of innate anxiety.

  4. This study demonistrated that Cacna2d1 gene expression in mouse dorsal raphe nucleus

  5. association of calcium channel alpha2/delta subunit 1 and ATP5b (show ATP5B Antibodies) occurs in intracellular membranes and at the plasma membrane of developing muscle cells, where they form a signaling complex capable of accelerating the rate of decline of calcium transients

  6. mechanism of Cavalpha2delta1-mediated spinal sensitization in which elevated Cavalpha2delta1 causes increased pre-synaptic glutamate (show GRIN1 Antibodies) release that leads to reduced excitation thresholds of post-synaptic dorsal horn neurons to innocuous stimuli.

CACNA2D1 Antigen Profile

Protein Summary

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gene names and symbols associated with CACNA2D1

  • calcium channel, voltage-dependent, alpha 2/delta subunit 1 (CACNA2D1) antibody
  • calcium channel, voltage-dependent, alpha 2/delta subunit 1 (cacna2d1) antibody
  • calcium channel, voltage-dependent, alpha 2/delta subunit 1 (Cacna2d1) antibody
  • calcium channel, voltage-dependent, alpha2/delta subunit 1 (Cacna2d1) antibody
  • Ca(v)alpha2delta1 antibody
  • Cacna2 antibody
  • CACNA2D1 antibody
  • CACNL2A antibody
  • Cchl2a antibody
  • CCHLA2 antibody
  • DHSCCA antibody
  • DKFZp469K2211 antibody

Protein level used designations for CACNA2D1

calcium channel, voltage-dependent, alpha 2/delta subunit 1 , voltage-dependent calcium channel subunit alpha-2/delta-1-like , calcium channel, L type, alpha 2 polypeptide , dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit , voltage-dependent calcium channel subunit alpha-2/delta-1 , voltage-gated calcium channel subunit alpha-2/delta-1 , dihydropryridine-sensitive calcium channel alpha-2 subunit , dihydropyridine-sensitive calcium channel alpha 2 , Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type)

GENE ID SPECIES
463504 Pan troglodytes
708215 Macaca mulatta
100012746 Monodelphis domestica
100036724 Xenopus (Silurana) tropicalis
100171724 Pongo abelii
100463812 Ailuropoda melanoleuca
100566428 Anolis carolinensis
100595072 Nomascus leucogenys
781 Homo sapiens
100009105 Oryctolagus cuniculus
100728887 Cavia porcellus
768444 Gallus gallus
610342 Canis lupus familiaris
397377 Sus scrofa
282608 Bos taurus
12293 Mus musculus
25399 Rattus norvegicus
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