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Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 Proteins (CACNA2D3)

CACNA2D3 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Additionally we are shipping CACNA2D3 Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CACNA2D3 55799 Q8IZS8
CACNA2D3 12294 Q9Z1L5
Rat CACNA2D3 CACNA2D3 306243 Q8CFG5
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Top CACNA2D3 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details

CACNA2D3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
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Mouse (Murine) ,
,

More Proteins for Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) Interaction Partners

Human Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) interaction partners

  1. The risk of developing anaemia is increased in reproductive age women carriers of A allele of rs1868505 (CACNA2D3) and/or T allele of rs13194491 (HIST1H2BJ).

  2. CACNA2D3-mediated increase in intracellular calcium (Ca2 (show CA2 Proteins)+) can induce mitochondrial-mediated apoptosis.

  3. CACNA2D3 is a novel tumor suppressor gene responsible for the 3p21 deletion event that plays a critical suppressing role in the development and progression of esophageal squamous cell carcinoma.

  4. CACNA2D3 polymorphism rs1375515 plays important role in iron status and is associated with the levels of iron-related biomarkers, as well as with iron clinical phenotypes (normal, iron de fi cient and anaemic).

  5. Expression of CACNA2D3 mRNA is regulated in breast cancer cell lines by methylation in the CpG island located in the 5' regulatory region of the gene.

  6. High CACNA2D3 gene expression is assiciated with glioblastoma multiforme.

  7. In humans, study found single-nucleotide polymorphisms in alpha2delta3 that are associated with reduced acute heat pain sensitivity in healthy volunteers and chronic postsurgical back pain.

  8. did not detect submicroscopic deletion or duplication nor sequence alteration in either CACNA2D3 or WNT5A (show WNT5A Proteins) in ZLS-affected individuals

  9. Loss of CACNA2D3 expression through aberrant promoter hypermethylation may contribute to gastric carcinogenesis.

Mouse (Murine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) interaction partners

  1. our results identify a novel role for the alpha2delta3 auxiliary subunit in the structure and function of specific synapses in the mammalian auditory pathway and in auditory processing disorders.

  2. Mice mutant for the stj ortholog CACNA2D3 (alpha2delta3) exhibit impaired behavioral heat pain sensitivity.

CACNA2D3 Protein Profile

Protein Summary

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gene names and symbols associated with CACNA2D3

  • calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3)
  • calcium channel, voltage-dependent, alpha 2/delta subunit 3 (cacna2d3)
  • calcium channel, voltage-dependent, alpha2/delta subunit 3 (Cacna2d3)
  • Cacnad3 protein
  • HSA272268 protein

Protein level used designations for CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta 3 subunit , voltage-dependent calcium channel subunit alpha-2/delta-3 , calcium channel, voltage-dependent, alpha 2/delta subunit 3 , calcium channel, voltage-dependent, alpha 2/delta 3 subunit-like , voltage-dependent calcium channel subunit alpha-2/delta-3-like , calcium channel alpha2-delta3 subunit , voltage-gated calcium channel subunit alpha-2/delta-3 , alpha 2 delta-3 , alpha2delta3 , calcium channel, voltage dependent, alpha2/delta subunit 3

GENE ID SPECIES
415996 Gallus gallus
460457 Pan troglodytes
476585 Canis lupus familiaris
519644 Bos taurus
100148645 Danio rerio
100400467 Callithrix jacchus
100448999 Pongo abelii
55799 Homo sapiens
12294 Mus musculus
306243 Rattus norvegicus
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