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CACNB2 encodes a subunit of a voltage-dependent calcium channel protein which is a member of the voltage-gated calcium channel superfamily. Additionally we are shipping Calcium Channel, Voltage-Dependent, beta 2 Subunit Proteins (6) and many more products for this protein.
Showing 10 out of 139 products:
Human Polyclonal CACNB2 Primary Antibody for EIA, WB - ABIN950994
Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010
Show all 3 references for ABIN950994
Human Monoclonal CACNB2 Primary Antibody for ICC, IF - ABIN863125
Dolphin: Beta subunits of voltage-gated calcium channels. in Journal of bioenergetics and biomembranes 2004
Show all 3 references for ABIN863125
Cow (Bovine) Polyclonal CACNB2 Primary Antibody for WB - ABIN2776359
Uhl, Liu, Drgon, Johnson, Walther, Rose, David, Niaura, Lerman: Molecular genetics of successful smoking cessation: convergent genome-wide association study results. in Archives of general psychiatry 2008
Human Polyclonal CACNB2 Primary Antibody for WB - ABIN265037
Perez-Reyes, Castellano, Kim, Bertrand, Baggstrom, Lacerda, Wei, Birnbaumer: Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel. in The Journal of biological chemistry 1992
Chicken Polyclonal CACNB2 Primary Antibody for WB - ABIN2774680
Foell, Balijepalli, Delisle, Yunker, Robia, Walker, McEnery, January, Kamp: Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization. in Physiological genomics 2004
Cow (Bovine) Polyclonal CACNB2 Primary Antibody for WB - ABIN2774679
Harry, Kobrinsky, Abernethy, Soldatov: New short splice variants of the human cardiac Cavbeta2 subunit: redefining the major functional motifs implemented in modulation of the Cav1.2 channel. in The Journal of biological chemistry 2004
Five serious mental disorders and three major cardiovascular diseases have recently been linked to the CACNB2 gene coding for the Cavbeta2 subunits
ADM (show ADM Antibodies) genotype AA was associated with the highest values of systolic and diastolic blood pressure (BP), while CACNB2 genotype CC carriers had the highest values of diastolic BP in childhood.
In the gene-based analysis, CACNB2 and CTCF (show CTCF Antibodies) showed the strongest evidence for association with schizophrenia in both the present samples and in those of the Psychiatric Genetics Consortium datasets.
Chronic atrial fibrillation increases miR (show MLXIP Antibodies)-21 expression in human atrial myocytes and decreases I(Ca,L) density by downregulating CACNA1C (show CACNA1C Antibodies)/CACNB2 expression.
Three rare missense mutations of CACNB2 (G167S, S197F, and F240L) found in Autism Spectrum Disorders (ASD (show ARSD Antibodies))-affected families, are reported.
High prevalence of CACNA2D1 (show CACNA2D1 Antibodies), SCN5A (show SCN5A Antibodies), and CACNB2 genetic variants in the Danish population previously associated with Brugada syndrome has been found in new exome data.
Association of the SNP rs2932538 in MOV10 and SNP rs4373814 in CACNB2 with an increased risk of hypertension in a Chinese Han population.
Genetic variations in CYP17A1 (show CYP17A1 Antibodies), CACNB2 and PLEKHA7 (show PLEKHA7 Antibodies) were related to blood pressure traits and/or hypertension in Chinese She population.
Genetic testing reveals disease-causing mutations in depolarizing sodium (SCN5A (show SCN5A Antibodies)) or calcium (CaCNB2b) channels in 5 infants with rapid ventricular tachycardia, conduction abnormalities, and Brugada-like syndrome.
This study provided that cacnb2 are associated with Bipolar I in the Han Chinese population.
Membrane Interaction of the beta2e Subunit of Voltage-Gated Ca(2 (show CA2 Antibodies)+) Channels
Dynamic phospholipid interaction of beta2e subunit regulates the gating of voltage-gated Ca2 (show CA2 Antibodies)+ channels.
a model in which CaVbeta promotes anterograde trafficking of the L-type channels by anchoring them to actin filaments in their itinerary to the plasma membrane.
We conclude that phosphorylation of the C-terminal sites in Ca(v)beta(2), Ser (show SIGLEC1 Antibodies)(1928), Ser (show SIGLEC1 Antibodies)(1512), and Ser (show SIGLEC1 Antibodies)(1570) of the Ca(v)1.2 (show CACNA1C Antibodies) protein is functionally not involved in the adrenergic regulation of the murine cardiac Ca(v)1.2 (show CACNA1C Antibodies) channel.
phosphorylation event is one mechanism underlying ahnak1 (show AHNAK Antibodies)'s modulator function on Cav1.2 (show CACNA1C Antibodies) channel activity.
Mice with cardiac-specific sequestration of the beta-subunit (show POLG Antibodies) of the L-type calcium channel
preferential binding between Cacna1c (show CACNA1C Antibodies) and Cacnb2 in the heart
Ca(V)beta(2) has an essential role in regulating the abundance and properties of Ca(V)1.3 (show CACNA1D Antibodies) channels in IHCs and, thereby, is critical for IHC development and synaptic encoding of sound.
expression of various CaVbeta2 proteins may be used to adapt the properties of LTCCs to changing myocardial requirements during development
This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described.
calcium channel, voltage-dependent, beta 2 subunit
, L-type calcium channel beta subunit
, voltage-dependent L-type calcium channel subunit beta-2
, voltage-dependent L-type calcium channel subunit beta-2-like
, calcium channel voltage-dependent subunit beta 2
, lambert-Eaton myasthenic syndrome antigen B
, myasthenic (Lambert-Eaton) syndrome antigen B
, cardiac calcium channel beta subunit
, cardiac calcium channel beta-subunit