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anti-Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2) Antibodies

The protein encoded by CACNG2 is a type I transmembrane AMPA receptor regulatory protein (TARP). Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CACNG2 12300 O88602
CACNG2 84347  
CACNG2 10369 Q9Y698
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Top anti-Calcium Channel, Voltage-Dependent, gamma Subunit 2 Antibodies at antibodies-online.com

Showing 10 out of 107 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Mouse Mouse Un-conjugated ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$383.90
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Rat Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Rat Rabbit Un-conjugated IP, WB   100 μg Log in to see 8 to 10 Days
$881.83
Details
Mouse Mouse HRP ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Mouse Mouse FITC ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Mouse Mouse Alkaline Phosphatase (AP) ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Mouse Mouse Biotin ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details

CACNG2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Human ,
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Top referenced anti-Calcium Channel, Voltage-Dependent, gamma Subunit 2 Antibodies

  1. Human Polyclonal CACNG2 Primary Antibody for WB - ABIN265040 : Hofmann, Lacinová, Klugbauer: Voltage-dependent calcium channels: from structure to function. in Reviews of physiology, biochemistry and pharmacology 1999 (PubMed)
    Show all 7 references for ABIN265040

  2. Mouse (Murine) Polyclonal CACNG2 Primary Antibody for WB - ABIN372715 : Tomita, Adesnik, Sekiguchi, Zhang, Wada, Howe, Nicoll, Bredt: Stargazin modulates AMPA receptor gating and trafficking by distinct domains. in Nature 2005 (PubMed)

  3. Mouse (Murine) Monoclonal CACNG2 Primary Antibody for ICC, IF - ABIN1686631 : Khodosevich, Jacobi, Farrow, Schulmann, Rusu, Zhang, Sprengel, Monyer, von Engelhardt: Coexpressed auxiliary subunits exhibit distinct modulatory profiles on AMPA receptor function. in Neuron 2014 (PubMed)

More Antibodies against Calcium Channel, Voltage-Dependent, gamma Subunit 2 Interaction Partners

Mouse (Murine) Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2) interaction partners

  1. the density of AMPARs correlates with that of TARP gamma-2 across SCC (show CYP11A1 Antibodies) synapses and its high expression is linked to high-density AMPAR expression at perforated type of pyramidal cell synapses

  2. in the absence of stargazin, the refinement of the retinogeniculate synapse is specifically disrupted during the experience-dependent phase. Stargazin expression and phosphorylation increased with visual deprivation.

  3. SR interacts with the synaptic proteins, postsynaptic density protein 95 (PSD-95 (show DLG4 Antibodies)) and stargazin, forming a ternary complex.

  4. Region-specific differences investigated in GABAA (show GABRg1 Antibodies) receptor (GABAAR (show GABRG2 Antibodies)) subunit expression occur in the ventral posterior and reticular thalamic nucleus regions in the stargazer mouse model of absence epilepsy.

  5. The combined loss of the AMPA (show GRIA3 Antibodies) receptor auxiliary TARPg-2 subunit and the GluK5 (show GRIK1 Antibodies) subunit leads to early mouse lethality.

  6. TARP gamma-2 was specifically expressed in cortical interneurons. Erbin (show ERBB2IP Antibodies) interacts with TARP gamma-2 and is crucial for its stability.

  7. This study suggested that, in stg, a trafficking defect in synaptic AMPARs in RTN cells leads to a compensatory increase in synaptic NMDARs and enhanced thalamic excitability.

  8. the loss of gamma-2 in stargazer mouse stellate cells induces changes in synaptic transmission that cannot be compensated for by the remaining TARP gamma-7 (show CACNG7 Antibodies).

  9. Results indicate that hippocampal and cerebellar long-term depression share a common pathway, namely dephosphorylation of stargazin by calcineurin (show PPP3CA Antibodies).

  10. Ataxic phenotype in stargazers is primarily due to absence of AMPA (show GRIA3 Antibodies) receptors at cerebellar mossy-fiber-granule cell synapses.

Human Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2) interaction partners

  1. A transient positive feedback mechanism between AMPAR and stargazin has implications for information processing in the brain, because it should allow activity-dependent facilitation of excitatory synaptic transmission through a postsynaptic mechanism.

  2. The additional cleft closure and/or stabilization of the more closed-cleft states of the LBD is expected to translate to higher agonist efficacy and could contribute to the structural mechanism for stargazin modulation of AMPAR function.

  3. Autoinactivation is a subunit and splice form dependent property of AMPA (show GRIA3 Antibodies) receptor-stargazin complexes, which involves structural rearrangements within the complex rather than any physical dissociation.

  4. Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2

  5. examined distribution of the stargazin-like proteins gamma2, gamma3, and gamma4 in human CNS: gamma2 is expressed in cerebellum, cerebral cortex, hippocampus and thalamus, whereas gamma3 abounds in cerebral cortex & amygdala and gamma4 in basal ganglia

  6. These results suggest that stargazin (gamma-2) not only promotes AMPA (show GRIA3 Antibodies) receptor surface expression but also directly modulates AMPA (show GRIA3 Antibodies) receptor activity.

  7. AMPA (show GRIA3 Antibodies) receptors complexed with stargazin are significantly more responsive to synaptically released glutamate (show GRIN1 Antibodies) compared with AMPA (show GRIA3 Antibodies) receptors lacking stargazin.

  8. Stargazin enhances trafficking of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA (show GRIA3 Antibodies)) receptors GluR1 (show GRIA1 Antibodies) and GluR2 (show GRIA2 Antibodies) by blocking endoplasmic reticulum retention.

  9. the Q/R site modulates the interaction of stargazin with the transmembrane domains of AMPA (show GRIA3 Antibodies) receptors via an allosteric mechanism and that this modulation leads to the observed differences in the electrophysiological properties of the receptor

  10. Stargazin polymorphisms may play a role in the response to lithium treatment.

Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2) Antigen Profile

Protein Summary

The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for schizophrenia.

Gene names and symbols associated with CACNG2

  • calcium channel, voltage-dependent, gamma subunit 2 (CACNG2) antibody
  • calcium channel, voltage-dependent, gamma subunit 2a (cacng2a) antibody
  • calcium channel, voltage-dependent, gamma subunit 2 (cacng2) antibody
  • calcium channel, voltage-dependent, gamma subunit 2 (Cacng2) antibody
  • AW060990 antibody
  • B230105C07Rik antibody
  • B930041E13Rik antibody
  • CACNG2 antibody
  • Ipr328 antibody
  • MRD10 antibody
  • stargazer antibody
  • stargazin antibody
  • stg antibody
  • wag antibody
  • waggler antibody
  • zgc:64200 antibody

Protein level used designations for CACNG2

voltage-dependent calcium channel gamma-2 subunit , calcium channel, voltage-dependent, gamma subunit 2 , TARP gamma 2 , TARP gamma-2 , neuronal voltage-gated calcium channel gamma-2 subunit , transmembrane AMPAR regulatory protein gamma-2 , stargazin

GENE ID SPECIES
286800 Bos taurus
393614 Danio rerio
427909 Gallus gallus
458799 Pan troglodytes
481279 Canis lupus familiaris
100125024 Xenopus (Silurana) tropicalis
100546076 Meleagris gallopavo
12300 Mus musculus
84347 Rattus norvegicus
10369 Homo sapiens
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