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Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2) ELISA Kits

The protein encoded by CACNG2 is a type I transmembrane AMPA receptor regulatory protein (TARP). Additionally we are shipping Calcium Channel, Voltage-Dependent, gamma Subunit 2 Antibodies (104) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse CACNG2 CACNG2 12300 O88602
Anti-Rat CACNG2 CACNG2 84347  
Anti-Human CACNG2 CACNG2 10369 Q9Y698
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More ELISA Kits for Calcium Channel, Voltage-Dependent, gamma Subunit 2 Interaction Partners

Mouse (Murine) Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2) interaction partners

  1. the density of AMPARs correlates with that of TARP gamma-2 across SCC (show CYP11A1 ELISA Kits) synapses and its high expression is linked to high-density AMPAR expression at perforated type of pyramidal cell synapses

  2. in the absence of stargazin, the refinement of the retinogeniculate synapse is specifically disrupted during the experience-dependent phase. Stargazin expression and phosphorylation increased with visual deprivation.

  3. SR interacts with the synaptic proteins, postsynaptic density protein 95 (PSD-95 (show DLG4 ELISA Kits)) and stargazin, forming a ternary complex.

  4. Region-specific differences investigated in GABAA (show GABRg1 ELISA Kits) receptor (GABAAR (show GABRG2 ELISA Kits)) subunit expression occur in the ventral posterior and reticular thalamic nucleus regions in the stargazer mouse model of absence epilepsy.

  5. The combined loss of the AMPA (show GRIA3 ELISA Kits) receptor auxiliary TARPg-2 subunit and the GluK5 (show GRIK1 ELISA Kits) subunit leads to early mouse lethality.

  6. TARP gamma-2 was specifically expressed in cortical interneurons. Erbin (show ERBB2IP ELISA Kits) interacts with TARP gamma-2 and is crucial for its stability.

  7. This study suggested that, in stg, a trafficking defect in synaptic AMPARs in RTN cells leads to a compensatory increase in synaptic NMDARs and enhanced thalamic excitability.

  8. the loss of gamma-2 in stargazer mouse stellate cells induces changes in synaptic transmission that cannot be compensated for by the remaining TARP gamma-7 (show CACNG7 ELISA Kits).

  9. Results indicate that hippocampal and cerebellar long-term depression share a common pathway, namely dephosphorylation of stargazin by calcineurin (show PPP3CA ELISA Kits).

  10. Ataxic phenotype in stargazers is primarily due to absence of AMPA (show GRIA3 ELISA Kits) receptors at cerebellar mossy-fiber-granule cell synapses.

Human Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2) interaction partners

  1. A transient positive feedback mechanism between AMPAR and stargazin has implications for information processing in the brain, because it should allow activity-dependent facilitation of excitatory synaptic transmission through a postsynaptic mechanism.

  2. The additional cleft closure and/or stabilization of the more closed-cleft states of the LBD is expected to translate to higher agonist efficacy and could contribute to the structural mechanism for stargazin modulation of AMPAR function.

  3. Autoinactivation is a subunit and splice form dependent property of AMPA (show GRIA3 ELISA Kits) receptor-stargazin complexes, which involves structural rearrangements within the complex rather than any physical dissociation.

  4. Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2

  5. examined distribution of the stargazin-like proteins gamma2, gamma3, and gamma4 in human CNS: gamma2 is expressed in cerebellum, cerebral cortex, hippocampus and thalamus, whereas gamma3 abounds in cerebral cortex & amygdala and gamma4 in basal ganglia

  6. These results suggest that stargazin (gamma-2) not only promotes AMPA (show GRIA3 ELISA Kits) receptor surface expression but also directly modulates AMPA (show GRIA3 ELISA Kits) receptor activity.

  7. AMPA (show GRIA3 ELISA Kits) receptors complexed with stargazin are significantly more responsive to synaptically released glutamate (show GRIN1 ELISA Kits) compared with AMPA (show GRIA3 ELISA Kits) receptors lacking stargazin.

  8. Stargazin enhances trafficking of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA (show GRIA3 ELISA Kits)) receptors GluR1 (show GRIA1 ELISA Kits) and GluR2 (show GRIA2 ELISA Kits) by blocking endoplasmic reticulum retention.

  9. the Q/R site modulates the interaction of stargazin with the transmembrane domains of AMPA (show GRIA3 ELISA Kits) receptors via an allosteric mechanism and that this modulation leads to the observed differences in the electrophysiological properties of the receptor

  10. Stargazin polymorphisms may play a role in the response to lithium treatment.

Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for schizophrenia.

Gene names and symbols associated with CACNG2

  • calcium channel, voltage-dependent, gamma subunit 2 (CACNG2) antibody
  • calcium channel, voltage-dependent, gamma subunit 2a (cacng2a) antibody
  • calcium channel, voltage-dependent, gamma subunit 2 (cacng2) antibody
  • calcium channel, voltage-dependent, gamma subunit 2 (Cacng2) antibody
  • AW060990 antibody
  • B230105C07Rik antibody
  • B930041E13Rik antibody
  • CACNG2 antibody
  • Ipr328 antibody
  • MRD10 antibody
  • stargazer antibody
  • stargazin antibody
  • stg antibody
  • wag antibody
  • waggler antibody
  • zgc:64200 antibody

Protein level used designations for CACNG2

voltage-dependent calcium channel gamma-2 subunit , calcium channel, voltage-dependent, gamma subunit 2 , TARP gamma 2 , TARP gamma-2 , neuronal voltage-gated calcium channel gamma-2 subunit , transmembrane AMPAR regulatory protein gamma-2 , stargazin

GENE ID SPECIES
286800 Bos taurus
393614 Danio rerio
427909 Gallus gallus
458799 Pan troglodytes
481279 Canis lupus familiaris
100125024 Xenopus (Silurana) tropicalis
100546076 Meleagris gallopavo
12300 Mus musculus
84347 Rattus norvegicus
10369 Homo sapiens
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