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CASK encodes a calcium/calmodulin-dependent serine protein kinase. Additionally we are shipping Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) Proteins (7) and Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) Kits (4) and many more products for this protein.
Showing 10 out of 76 products:
Dog (Canine) Monoclonal CASK Primary Antibody for IF, IP - ABIN968174
Borg, Lõpez-Figueroa, de Taddèo-Borg, Kroon, Turner, Watson, Margolis: Molecular analysis of the X11-mLin-2/CASK complex in brain. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1999
Show all 5 references for ABIN968174
Rat (Rattus) Polyclonal CASK Primary Antibody for WB - ABIN1881710
Butz, Okamoto, Südhof: A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. in Cell 1998
Show all 5 references for ABIN1881710
Human Polyclonal CASK Primary Antibody for EIA, IHC (p) - ABIN359407
Stevenson, Laverty, Wenwieser, Douglas, Wilson: Mapping and expression analysis of the human CASK gene. in Mammalian genome : official journal of the International Mammalian Genome Society 2000
Show all 3 references for ABIN359407
Human Polyclonal CASK Primary Antibody for IHC (p), WB - ABIN391318
Gallivan, Crombleholme, DAlton: Early prenatal diagnosis of choledochal cyst. in Prenatal diagnosis 1997
Data show that Drosophila CASK is associated with both pre and postsynaptic membranes, and that loss of presynaptic CASK leads to less evoked synaptic transmission, fewer spontaneous synaptic events, and reduced synaptic vesicle cycling.
Full-length CASK-beta appears to have a unique role within central circuits that control motor output
Camguk localizes to synaptic regions of the brain and associates in an ATP-regulated manner with CaMKII (show CAMK2 Antibodies) to catalyze formation of a pool of calcium-insensitive CaMKII (show CAMK2 Antibodies).
The results of this study support the involvement of CAKI in neurotransmitter release and nervous system function.
the Drosophila homolog of CASK/Camguk can act as a gain controller on the transition to calcium-independence in vivo.
Dneurexin (DNRX (show NRXN1 Antibodies)) is important for locomotion through a genetic interaction with the scaffold protein (show HOMER1 Antibodies), CAKI/CMG, the Drosophila homolog of vertebrate CASK.
In clinical specimens, CASK was over-expressed in tumors and H. pylori positive tissues, and its mRNA levels were inversely correlated with miR (show MLXIP Antibodies)-203 expression.
Data indicate that patients with low calcium/calmodulin-dependent serine protein kinase (CASK) staining had a significantly better survival compared to patients with high CASK staining.
The findings suggest that CASK and the truncated prestin (show SLC26A5 Antibodies) splice isoform contribute to confinement of prestin (show SLC26A5 Antibodies) to the basolateral region of the plasma membrane.
CASK regulates CaMKII (show CAMK2G Antibodies) autophosphorylation in a pathway required for memory formation.
a model whereby CASK recruits FRMD7 (show FRMD7 Antibodies) to the plasma membrane to promote neurite outgrowth during development of the oculomotor neural network and that defects in this interaction result in nystagmus.
our findings suggest a molecular mechanism by which CASK binding regulates SAP97 (show DLG1 Antibodies) conformation and its subsequent sorting and synaptic targeting of AMPARs and NMDARs during trafficking to synapses.
CASK represents an intracellular gateway to regulate purinergic nociceptive signaling.
An early diagnosis and be useful for medical care of females with ID and MICPCH associated with CASK mutations.
CASK combines the scaffolding activity of MAGUKs with an unusual kinase activity that phosphorylates substrates recuited by the scaffolding activity.
During wounding, CASK is mobilized to the plasm (show GJA1 Antibodies)a membrane where it colocalizes with Cx43 and CADM1 1 hour after skin explant wounding.
Ths data of this study implies that some phenotypic components of CASK heterozygous deletion mutation associated disorders represent systemic manifestation of metabolic stress.
DLG1 (show DLG1 Antibodies) and CASK play critical cooperative roles in maintaining the nephron progenitor population, potentially via a mechanism involving effects on FGF signaling
Immunofluorescence shows colocalization of Cx43 (show GJA1 Antibodies) and CASK in brain astrocytes.
CASK negatively regulates PMCA4b (show ATP2B4 Antibodies) by directly binding to it and JAM-A (show F11R Antibodies) positively regulates it indirectly through CASK
Data show that CASK expression and the appropriate localization of DLG1 (show DLG1 Antibodies) and LIN7c (show LIN7C Antibodies) are not essential for either epithelial polarity or intestinal homeostasis in vivo.
Post-translational modifications to CASK are major regulatory steps leading to its proteasomal degradation.
CASK is transcribed in mouse testis and processing may play a role in the acquisition of spserm and sperm functions.
CASK and Dlg (show DLG4 Antibodies) may act as a scaffold for organizing receptors and channels at the postsynaptic membrane of the neuromuscular junction.
We suggest that Tbr-1 (show TBR1 Antibodies)/CASK protein complex regulates expression of these downstream target genes and thus modulates neuronal activity and function.
findings suggest that Cask plays an important role in all retinal synapses
This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
, Calcium/calmodulin-dependent protein kinase
, Camguk/CASK adaptor protein
, calmodulin-dependent kinase
, Peripheral plasma membrane protein CASK
, peripheral plasma membrane protein CASK
, calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase
, protein lin-2 homolog
, trinucleotide repeat containing 8
, G-protein-coupled receptor GPR34