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The protein encoded by CACYBP is a calcyclin binding protein. Additionally we are shipping Calcyclin Binding Protein Kits (29) and Calcyclin Binding Protein Proteins (14) and many more products for this protein.
Showing 10 out of 98 products:
Human Monoclonal CACYBP Primary Antibody for WB - ABIN393386
Sowa, Bennett, Gygi, Harper: Defining the human deubiquitinating enzyme interaction landscape. in Cell 2009
Show all 5 references for ABIN393386
Chicken Polyclonal CACYBP Primary Antibody for WB - ABIN2784483
Santelli, Leone, Li, Fukushima, Preece, Olson, Ely, Reed, Pellecchia, Liddington, Matsuzawa: Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex. in The Journal of biological chemistry 2005
CacyBP/SIP nuclear translocation contributes to the proliferation of gastric cancer cells, and CacyBP/SIP exerts this effect, at least in part, by stimulating ubiquitin-mediated degradation of p27Kip1 (show CDKN1B Antibodies).
CacyBP/SIP plays an important role in inhibiting apoptosis of glioma cells which might be mediated by ERK1/2 (show MAPK1/3 Antibodies) signaling pathway.
CacyBP/SIP is a useful indicator of dis processes in Chronic Lymphocytic Leukemia (CLL) and plays an important role in sustaining the balance of cell proliferation and apoptosis.
CacyBP/SIP nuclear translocation promotes the proliferation and cell cycle progression of gastric cancer cells.
Overexpression of CacyBP is associated with glioma.
This study presents CacyBP as a promising candidate biomarker for colorectal cancer (CRC (show CALR Antibodies)) metastasis and also sheds light on the underlying molecular mechanism by which CacyBP promotes CRC (show CALR Antibodies) metastasis.
CacyBP enhances multidrug resistance of pancreatic cancer cells by regulation of P-gp (show ABCB4 Antibodies) and Bcl-2 (show BCL2 Antibodies).
These findings reveal a novel function for SNRK (show SNRK Antibodies) in the regulation of colon cancer cell proliferation and beta-catenin (show CTNNB1 Antibodies) signaling.
different activity of CacyBP/SIP in neuroblastoma (show ARHGEF16 Antibodies) NB2a and colon cancer HCT116 cells might affect the ERK1/2 (show MAPK1/3 Antibodies) pathway in the differentiation or proliferation processes
new insight into the interaction between S100 proteins and CacyBP/SIP
sumoylated CacyBP/SIP is present in the cytoplasmic and not in the nuclear fraction. We have also established that lysine 16 is the residue which undergoes sumoylation in the CacyBP/SIP protein.
SIP (-/-) embryonic fibroblasts have increased levels of cytosolic p27 (show CDKN1B Antibodies) and exhibit increased cell motility compared to wild-type cells.
CacyBP/SIP exhibits a phosphatase activity toward ERK1/2 (show MAPK1/3 Antibodies) kinases while its E217K (show Ube2g1 Antibodies) mutant does not.
Cacybp is associated with acute lung injury
Data indicated that CacyBP/SIP could simultaneously interact with tubulin (show TUBB Antibodies) and actin, suggesting that CacyBP/SIP might link actin and tubulin (show TUBB Antibodies) cytoskeletons.
binds EF-hand proteins of the S100 family [CacyBP/SIP]
Structural details of multiple sites of protein-protein interactions on SIP provide insight into the mechanism that drives the formation of the Siah-1 E3 ubiquitin ligase complex [SIP]
SIP (CacyBP)-thymocytes have an impaired pre-TCR checkpoint with failure of TCRbeta gene rearrangement and increased apoptosis, resulting in reduced cellularity of the thymus.
The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, calcyclin binding protein
, Calcyclin binding protein
, S100A6-binding protein
, Siah-interacting protein (SIP)
, growth-inhibiting gene 5 protein
, siah-interacting protein