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Calmegin is a testis-specific endoplasmic reticulum chaperone protein. Additionally we are shipping Calmegin Antibodies (37) and Calmegin Kits (2) and many more products for this protein.
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Although their similarity in carbohydrate binding specificities is high, there seems to be some differences in the mode of substrate recognition between calmegin and calnexin (show CANX Proteins).
calmegin expression is regulated by histone deacetylase (show HDAC1 Proteins) and CpG methyltransferase in a coordinative way
The sperm defect in calmegin-null animals is not at the level of sperm-EPM (show STX2 Proteins) binding but rather may involve either sperm-ZP binding and/or sperm transit to the oviduct.
Calmegin-knockout sperm, even when they were combined in chimeric ejaculates with wild-type sperm, remained outside of the uterotubal junction.
Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility.
, MEG 1 antigen