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Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.. Additionally we are shipping CAPN1 Antibodies (121) and CAPN1 Proteins (8) and many more products for this protein.
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CRYbetaA3/A1-crystallin has a role in preventing nuclear cataract impaired lysosomal cargo clearance and calpain activation
Capn1 (show CAPNL1 ELISA Kits) protein and activity in mitochondria were elevated in diabetic mouse hearts. Increased mitochondrial Capn1 (show CAPNL1 ELISA Kits) was associated with increased mitochondrial ROS (show ROS1 ELISA Kits) generation and oxidative damage and reduced ATP5A1 (show ATP5A1 ELISA Kits) protein and ATP synthase activity.
LOX-1 (show OLR1 ELISA Kits) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 and -2.
Over-expression of Cast inhibits calpain activation and attenuates post-infarction myocardial remodeling.
Junctophilin-2 (show JPH2 ELISA Kits) is cleaved by calpain at multiple sites, resulting in dysfunctional junctophilin-2 (show JPH2 ELISA Kits) truncations.
Data indicate that calpain-1 up-regulation induces endoplasmic reticulum (ER) stress.
Calcitriol stimulates expression of mu-calpain (show CAPNL1 ELISA Kits) in co-cultured mouse cells.
Data suggest that vitamin D3 up-regulates skeletal muscle fat deposition, up-regulates muscle u-calpain/Capn1 and m-calpain/Capn2 (show CAPN2 ELISA Kits) expression, and down-regulates muscle calpastatin (show CAST ELISA Kits) expression.
Calpain-mediated MFN2 (show MFN2 ELISA Kits) degradation is a novel mechanism regulating mitochondrial fusion during glutamate (show GRIN1 ELISA Kits) excitotoxicity.
in spinal cord of 30 day old mice, activation of calpain-1 produces high amounts of nNOS (show NOS1 ELISA Kits) active species, while in 120 day old mice enhanced-prolonged activation of calpain-1 inactivates nNOS (show NOS1 ELISA Kits) and down-regulates NR2B (show GRIN2B ELISA Kits)
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
calpain 1, large subunit
, CANP 1
, calcium-activated neutral proteinase 1
, calpain mu-type
, calpain-1 catalytic subunit
, calpain-1 large subunit
, calpain 1