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Calpain 1 Proteins (CAPN1)

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.. Additionally we are shipping CAPN1 Antibodies (92) and CAPN1 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse CAPN1 CAPN1 12333 O35350
CAPN1    
CAPN1    
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Top CAPN1 Proteins at antibodies-online.com

Showing 5 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$430.50
Details
Pig Pig Un-conjugated 100 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Human Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$656.07
Details
HOST_Human Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$134.44
Details
Human Un-conjugated   2 μg Log in to see 6 Days
$391.29
Details

CAPN1 Proteins by Origin and Source

Origin Expressed in
Human
Pig (Porcine)

Top referenced CAPN1 Proteins

  1. Human CAPN1 Protein expressed in Human - ABIN411905 : Huang, Zhou, Saberwal, Konieczna, Horvath, Katsoulidis, Platanias, Eklund: Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription. in Molecular and cellular biology 2010 (PubMed)
    Show all 7 references for ABIN411905

More Proteins for Calpain 1 (CAPN1) Interaction Partners

Mouse (Murine) Calpain 1 (CAPN1) interaction partners

  1. CRYbetaA3/A1-crystallin has a role in preventing nuclear cataract impaired lysosomal cargo clearance and calpain activation

  2. Capn1 (show CAPNL1 Proteins) protein and activity in mitochondria were elevated in diabetic mouse hearts. Increased mitochondrial Capn1 (show CAPNL1 Proteins) was associated with increased mitochondrial ROS (show ROS1 Proteins) generation and oxidative damage and reduced ATP5A1 (show ATP5A1 Proteins) protein and ATP synthase activity.

  3. LOX-1 (show OLR1 Proteins) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 and -2.

  4. Over-expression of Cast inhibits calpain activation and attenuates post-infarction myocardial remodeling.

  5. Junctophilin-2 (show JPH2 Proteins) is cleaved by calpain at multiple sites, resulting in dysfunctional junctophilin-2 (show JPH2 Proteins) truncations.

  6. Data indicate that calpain-1 up-regulation induces endoplasmic reticulum (ER) stress.

  7. Calcitriol stimulates expression of mu-calpain (show CAPNL1 Proteins) in co-cultured mouse cells.

  8. Data suggest that vitamin D3 up-regulates skeletal muscle fat deposition, up-regulates muscle u-calpain/Capn1 and m-calpain/Capn2 (show CAPN2 Proteins) expression, and down-regulates muscle calpastatin (show CAST Proteins) expression.

  9. Calpain-mediated MFN2 (show MFN2 Proteins) degradation is a novel mechanism regulating mitochondrial fusion during glutamate (show GRIN1 Proteins) excitotoxicity.

  10. in spinal cord of 30 day old mice, activation of calpain-1 produces high amounts of nNOS (show NOS1 Proteins) active species, while in 120 day old mice enhanced-prolonged activation of calpain-1 inactivates nNOS (show NOS1 Proteins) and down-regulates NR2B (show GRIN2B Proteins)

CAPN1 Protein Profile

Protein Summary

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

Gene names and symbols associated with Calpain 1 Proteins (CAPN1)

  • calpain 1 (CAPN1)
  • calpain 1 (Capn1)
  • zgc:55262 (zgc:55262)
  • Capa-1 protein
  • Capa1 protein
  • Capn1 protein
  • fj67g01 protein
  • mu-calpin protein
  • wu:fj67g01 protein

Protein level used designations for Calpain 1 Proteins (CAPN1)

calpain 1, large subunit , CANP 1 , calcium-activated neutral proteinase 1 , calpain mu-type , calpain-1 catalytic subunit , calpain-1 large subunit , micromolar-calpain , mu-calpain , muCANP , calpain 1

GENE ID SPECIES
443130 Ovis aries
12333 Mus musculus
406768 Danio rerio
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