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Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.. Additionally we are shipping CAPN1 Kits (11) and CAPN1 Proteins (8) and many more products for this protein.
Showing 10 out of 132 products:
Cow (Bovine) Polyclonal CAPN1 Primary Antibody for IP, IHC - ABIN1582151
Li, Shi, Han, Wang, Yang, Cao, Jiao: Effects of ARHI on cell cycle progression and apoptosis levels of breast cancer cells. in Tumour biology 2012
Cow (Bovine) Monoclonal CAPN1 Primary Antibody for ICC, IHC (fro) - ABIN267206
Viringipurampeer, Shan, Gregory-Evans, Zhang, Mohammadi, Gregory-Evans: Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafish. in Cell death and differentiation 2014
Cow (Bovine) Polyclonal CAPN1 Primary Antibody for WB - ABIN222978
Jayanthi, Deng, Noailles, Ladenheim, Cadet: Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004
Human Polyclonal CAPN1 Primary Antibody for IF (cc), IF (p) - ABIN737646
Miners, Renfrew, Swirski, Love: Accumulation of ¿-synuclein in dementia with Lewy bodies is associated with decline in the ¿-synuclein-degrading enzymes kallikrein-6 and calpain-1. in Acta neuropathologica communications 2014
Human Polyclonal CAPN1 Primary Antibody for IHC (p), WB - ABIN965738
Imajoh, Aoki, Ohno, Emori, Kawasaki, Sugihara, Suzuki: Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease. in Biochemistry 1989
Results indicate that calpain-1 and calpain-2 (show CAPN2 Antibodies) are differentially activated in hippocampus following seizure activity, with calpain-1 activation being limited to a small population of interneurons, and possibly triggering neuroprotective events, while calpain-2 (show CAPN2 Antibodies) is widely activated in pyramidal neurons of CA1 (show CA1 Antibodies) and CA3 (show CA3 Antibodies), and triggers neurodegenerative cascades.
Here we show the combined loss of glial glutamate (show GRIN1 Antibodies) transporters GLT1 (show SLC1A2 Antibodies) and GLAST (show SLC1A3 Antibodies) in spinal cord caused motor neuronal death and hindlimb paralysis.
These results suggested that Streptococcus pneuomoniae PLY induces the influx of calcium in Streptococcus pneumoniae-infected macrophages, followed by calpain activation and subsequent IL-1alpha maturation and secretion.
High calpain expression is associated with brain injury.
the expression of the full-length 60-kDa calcineurin protein is down-regulated due to over-activated calpain that cleaves calcineurin to form a 45-kDa fragment.
calpains and calpastatin (show CAST Antibodies) in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (show TAGLN Antibodies)-5HTT (show SLC6A4 Antibodies)(+) strain) PH, were investigated.
Attenuation of atherosclerotic lesions/inflammation in ApoE (show APOE Antibodies) KO mice by simvastatin might be associated with the downregulation of CD36 (show CD36 Antibodies) and calpain-1.
Leukocyte calpain-1/calpain-2 (show CAPN2 Antibodies) deficiency reduces angiotensin II-induced inflammation and atherosclerosis but not abdominal Aortic aneurysms in mice.
TnT3 regulates transcription of Cacna1s (show CACNA1S Antibodies), the gene encoding Cav1.1 (show CACNA1S Antibodies). Knocking down TnT3 in vivo downregulated Cav1.1 (show CACNA1S Antibodies).
Taken together, our findings suggested that DHRS7C maintains intracellular Ca(2+) homeostasis involving the ER/SR and that functional loss of DHRS7C leads to Ca(2+) overload in the cytosol and ER/SR, resulting in enlarged cellular morphology via calpain activation
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
calpain 1, large subunit
, CANP 1
, calcium-activated neutral proteinase 1
, calpain mu-type
, calpain-1 catalytic subunit
, calpain-1 large subunit
, calpain 1