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Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (By similarity).. Additionally we are shipping Calpain 2 Proteins (5) and Calpain 2 Kits (3) and many more products for this protein.
Showing 10 out of 59 products:
Human Polyclonal Calpain 2 Primary Antibody for WB - ABIN223098
Chou, Huang, Chen, Li: Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2. in Cellular and molecular life sciences : CMLS 2010
Results indicate that calpain-1 (show CAPN1 Antibodies) and calpain-2 are differentially activated in hippocampus following seizure activity, with calpain-1 (show CAPN1 Antibodies) activation being limited to a small population of interneurons, and possibly triggering neuroprotective events, while calpain-2 is widely activated in pyramidal neurons of CA1 (show CA1 Antibodies) and CA3 (show CA3 Antibodies), and triggers neurodegenerative cascades.
these findings identify ASAP2 (show ASAP2 Antibodies) as a new target of Selk (show HSP Antibodies)-dependent palmitoylation and reveal a new mechanism regulating the efficiency of FcgammaR-mediated phagocytosis.
ENaC (show SCNN1A Antibodies) activity is regulated by calpain-2 proteolysis of MARCKS (show MARCKS Antibodies).
calpains and calpastatin (show CAST Antibodies) in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (show TAGLN Antibodies)-5HTT (show SLC6A4 Antibodies)(+) strain) PH, were investigated.
Leukocyte calpain-1 (show CAPN1 Antibodies)/calpain-2 deficiency reduces angiotensin II-induced inflammation and atherosclerosis but not abdominal Aortic aneurysms in mice.
These results suggest that TRPV1 (show TRPV1 Antibodies)/Ca(2 (show CA2 Antibodies)+)/calpain 2-dependent signaling plays a dominant role in capsaicin-induced ablation of nociceptive terminals and further our understanding of the molecular mechanisms underlying the effects of capsaicin on nociceptors.
Calpain-2 modulates pulmonary vascular remodeling in pulmonary arterial hypertension.
LOX-1 (show OLR1 Antibodies) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (show CAPN1 Antibodies) and -2.
Dicer is predominantly a Capn2 substrate. Dicer levels were altered in platelets from diabetic mice due to the cleavage of the enzyme by calpain, resulting in loss of function.
Data suggest that vitamin D3 up-regulates skeletal muscle fat deposition, up-regulates muscle m-calpain/Capn2 and u-calpain/Capn1 expression, and down-regulates muscle calpastatin expression.
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (By similarity).
80 kDa M-calpain subunit
, CANP 2
, calcium-activated neutral proteinase 2
, calpain M-type
, calpain-2 catalytic subunit
, calpain-2 large subunit
, cysteine proteinase
, m-calpain 80 kDa large subunit
, m-calpain large subunit
, calpain 2