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Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (By similarity).. Additionally we are shipping Calpain 2 Proteins (6) and Calpain 2 Kits (3) and many more products for this protein.
Showing 10 out of 52 products:
Human Polyclonal Calpain 2 Primary Antibody for WB - ABIN223098
Chou, Huang, Chen, Li: Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2. in Cellular and molecular life sciences : CMLS 2010
Leukocyte calpain-1 (show CAPN1 Antibodies)/calpain-2 deficiency reduces angiotensin II-induced inflammation and atherosclerosis but not abdominal Aortic aneurysms in mice.
These results suggest that TRPV1 (show TRPV1 Antibodies)/Ca(2 (show CA2 Antibodies)+)/calpain 2-dependent signaling plays a dominant role in capsaicin-induced ablation of nociceptive terminals and further our understanding of the molecular mechanisms underlying the effects of capsaicin on nociceptors.
Calpain-2 modulates pulmonary vascular remodeling in pulmonary arterial hypertension.
LOX-1 (show OLR1 Antibodies) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (show CAPN1 Antibodies) and -2.
Dicer is predominantly a Capn2 substrate. Dicer levels were altered in platelets from diabetic mice due to the cleavage of the enzyme by calpain, resulting in loss of function.
Data suggest that vitamin D3 up-regulates skeletal muscle fat deposition, up-regulates muscle m-calpain/Capn2 and u-calpain/Capn1 expression, and down-regulates muscle calpastatin expression.
Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 (show CAPN1 Antibodies) deficient mice.
Calpain-mediated proteolysis of tropomodulin isoforms TMOD1 (show TMOD1 Antibodies) and TMOD4 (show TMOD4 Antibodies) leads to thin filament elongation in dystrophic skeletal muscle.
extrasynaptic NMDAR (show GRIN1 Antibodies)-coupled m-calpain activation is neurodegenerative
Down-regulated expression of calpain-2 or talin-1, or pharmacological interference with calpain action, did not affect toxin binding but reduced endocytosis and increased the survival of cells exposed to anthrax lethal toxin.
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (By similarity).
80 kDa M-calpain subunit
, CANP 2
, calcium-activated neutral proteinase 2
, calpain M-type
, calpain-2 catalytic subunit
, calpain-2 large subunit
, cysteine proteinase
, m-calpain 80 kDa large subunit
, m-calpain large subunit
, calpain 2