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The protein encoded by CNN2, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. Additionally we are shipping Calponin 2 Antibodies (96) and Calponin 2 Kits (11) and many more products for this protein.
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Human CNN2 Protein expressed in Human - ABIN2713070
Debald, Jin, Linke, Walgenbach, Rauch, Zellmer, Fimmers, Kuhn, Hartmann, Walgenbach-Brünagel: Calponin-h2: a potential serum marker for the early detection of human breast cancer? in Tumour biology 2014
h2-Calponin gene expression is further affected by the treatment of cells with Notch (show NOTCH1 Proteins) inhibitor and activator, suggesting an upstream signaling mechanism.
Expressed h2-calponin is associated with actin-tropomyosin microfilaments and may regulate cytokinesis by inhibiting the activity of the actin cytoskeleton.
H2-calponin has a role in regulating macrophage motility and phagocytosis
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Two transcript variants encoding different isoforms have been found for this gene.
, calponin 1, basic, smooth muscle
, calponin H2, smooth muscle
, neutral calponin
, calponin 2 copy B