anti-Calsequestrin 1 (CASQ1) Antibodies

The protein encoded by CASQ1 is a mitochondrial calcium-binding protein located in the luminal space of the terminal cisternae of the sarcoplasmic reticulum. Additionally we are shipping Calsequestrin Kits (11) and Calsequestrin Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CASQ1 12372 O09165
CASQ1 844 P31415
CASQ1 686019 P19633
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Top anti-Calsequestrin Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Mouse Un-conjugated IF, WB Western blot analysis of Calsequestrin on a rat muscle lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-Calsequestrin antibody. 50 μg Log in to see 6 to 8 Days
$154.07
Details
Chicken Mouse Un-conjugated ICC, IF, IHC (p), IP, IHC, WB Figure 1 shows a Western blot of calsequestrin in canine skeletal muscle extract using ABIN266947. Immunohistochemistry-Paraffin: Calsequestrin 1 Antibody (VIIID12) [ABIN266947] - Both normal and cancer biopsies of deparaffinized Human skeletal muscle tissues. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Dog Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: Calsequestrin 1 Antibody [ABIN267179] - Analysis showing positive staining in the cytoplasm of Human heart tissue (right) compared with a negative control in the absence of primary antibody (left). Immunohistochemistry-Paraffin: Calsequestrin 1 Antibody [ABIN267179] - Analysis showing positive staining in the cytoplasm of Human skeletal muscle (right) compared with a negative control in the absence of primary antibody (left). 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: Calsequestrin 1 Antibody [NBP1-88181] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY420059) Immunohistochemistry-Paraffin: Calsequestrin 1 Antibody [NBP1-88181] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated WB Western Blot: Calsequestrin 1 Antibody [NBP2-15682] - Sample (50 ug of whole cell lysate) A: Mouse Heart, 10% SDS PAGE gel, diluted at 1:1000. Western Blot: Calsequestrin 1 Antibody [NBP2-15682] - Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$618.75
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$295.90
Details
Dog Mouse Un-conjugated WB   100 μL Log in to see 7 to 9 Days
$793.83
Details

CASQ1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) ,
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Human , ,
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Rat (Rattus) ,
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Top referenced anti-Calsequestrin Antibodies

  1. Chicken Monoclonal Calsequestrin Primary Antibody for ICC, IF - ABIN266947 : Leatherbury, Yu, Chatterjee, Walker, Yu, Tian, Lo: A novel mouse model of X-linked cardiac hypertrophy. in American journal of physiology. Heart and circulatory physiology 2008 (PubMed)
    Show all 8 Pubmed References

  2. Dog (Canine) Polyclonal Calsequestrin Primary Antibody for ICC, IF - ABIN267179 : Shankar, Messenberg, Chan, Underhill, Foster, Nabi: Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells. in Cancer research 2010 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Monoclonal Calsequestrin Primary Antibody for IF, WB - ABIN968625 : Kobayashi, Alseikhan, Jones: Localization and characterization of the calsequestrin-binding domain of triadin 1. Evidence for a charged beta-strand in mediating the protein-protein interaction. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal Calsequestrin Primary Antibody for IHC, IHC (p) - ABIN4287523 : Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. in Proteome science 2011 (PubMed)

More Antibodies against Calsequestrin Interaction Partners

Zebrafish Calsequestrin 1 (CASQ1) interaction partners

  1. Three zebrafish Casqs: Casq1a, Casq1b and Casq2 (show CASQ2 Antibodies) were identified by mass spectrometry (Data are available via ProteomeXchange with identifier PXD002455). Skeletal and cardiac zebrafish calsequestrins share properties with mammalian Casq1 and Casq2 (show CASQ2 Antibodies).

Mouse (Murine) Calsequestrin 1 (CASQ1) interaction partners

  1. Calcium entry activated by ablation of both JP45 (show JSRP1 Antibodies)-CASQ1 and JP45 (show JSRP1 Antibodies)-CASQ2 (show CASQ2 Antibodies) complexes supports tetanic force development in slow twitch soleus muscles.

  2. Transient knockdown of annexin A6 (show ANXA6 Antibodies) and calsequestrin 1 protein of high-active mice with vivo-morpholinos resulted in decreased physical activity levels (P = 0.001).

  3. Ca(2 (show CA2 Antibodies)+) transients evoked by tetanic stimulation are the result of massive Ca(2 (show CA2 Antibodies)+) influx due to enhanced Ca(v)1.1 (show CACNA1S Antibodies) channel activity, which restores muscle strength in JP45 (show JSRP1 Antibodies)/CASQ1 double knockout mice.

  4. Protein levels of CSQ1, SERCA1 (show ATP2A1 Antibodies), and SERCA2 (show ATP2A2 Antibodies) are re-adjusted in skeletal muscles depending on the demands of diverse exercise training programs.

  5. results support the view that in skeletal muscles, CASQ1 plays a key role in both Ca(2 (show CA2 Antibodies)+) homeostasis and terminal cisternae structure

  6. The results presented in this paper unmask a differential effect of CASQ1&2 ablation in fast versus slow fibers

  7. Calsequestrin not only stores Ca(2 (show CA2 Antibodies)+), but also varies its affinity in ways that progressively increase the ability of the store to deliver Ca(2 (show CA2 Antibodies)+) as it becomes depleted, a novel feedback mechanism of potentially valuable functional implications.

  8. effect of nockdown of CSQ1 in adult mouse skeletal muscle on Store-operated Ca(2 (show CA2 Antibodies)+) entry

  9. knocking down CSQ2, but not CSQ1, leads to reduced Ca2 (show CA2 Antibodies)+ storage and release in C2C12 myotubes

  10. CSQ1 is essential for the normal development of the sarcoplasmic reticulum (SR) and its calcium release units and for the storage and release of appropriate amounts of SR Ca(2 (show CA2 Antibodies)+).

Rabbit Calsequestrin 1 (CASQ1) interaction partners

  1. a mechanism for the observed in vitro and in vivo dynamic high-capacity and low-affinity Ca(2 (show CA2 Antibodies)+)-binding activity of calsequestrin

  2. Purified skeletal ryanodine receptors are similarly activated by purified triadin (show TRDN Antibodies) or purified junctin (show ASPH Antibodies) added to their luminal side, although a lack of competition indicated that the proteins act at independent sites.

Human Calsequestrin 1 (CASQ1) interaction partners

  1. the p.D244G variant in CASQ1 is associated with a skeletal muscle disease and alters sarcoplasmic calcium release

  2. Calsequestrin-1 monomers suppress Store-Operated Ca2 (show CA2 Antibodies)+ Entry by interacting with STIM1 (show STIM1 Antibodies) and attenuating STIM1 (show STIM1 Antibodies) aggregation via its C-terminal amino acid 362-396.

  3. the protein aggregate myopathy with benign evolution and muscle inclusions composed of excess CASQ1 due to the D244G heterozygous missense mutation in the CASQ1 gene

  4. Equilibrium dialysis and turbidity measurements showed that D244G and, to a lesser extent, M87T partially lose Ca(2 (show CA2 Antibodies)+) binding exhibited by wild type calsequestrin 1 at high Ca(2 (show CA2 Antibodies)+) concentrations.

  5. Missense mutation in CASQ1 gene causes the formation of abnormal sarcoplasmic reticulum (SR) vacuoles containing aggregates of CASQ1 results in altered Ca2 (show CA2 Antibodies)+ release, and vacuolar myopathy patients phenotype.

  6. The sarcoplasmic reticulum calcium content in human type II fibres is primarily determined by the CSQ1 abundance, and in type I fibres, by the combined amounts of both CSQ1 and CSQ2.

  7. a direct interaction of dysferlin (show DYSF Antibodies) with Trim72/MG53 (show TRIM72 Antibodies), AHNAK (show AHNAK Antibodies), cytoplasmic dynein (show DYNC1H1 Antibodies), myomesin-2 (show MYOM2 Antibodies) and calsequestrin-1, but not with caveolin-3 (show CAV3 Antibodies) or dystrophin (show DMD Antibodies), is reported.

  8. CASQ1 is not a major malignant hyperthermia susceptibility locus in the North American population

  9. Downregulation of CSQ-1 in diabetic platelets and impairment of CSQ-1 in normal cells leads to disturbed Ca(2 (show CA2 Antibodies)+) release, demonstrating a potential role for CSQ-1 in the regulation of the platelet Ca(2 (show CA2 Antibodies)+) release process

  10. a mechanism for the observed in vitro and in vivo dynamic high-capacity and low-affinity Ca(2 (show CA2 Antibodies)+)-binding activity of calsequestrin

Calsequestrin (CASQ1) Antigen Profile

Protein Summary

The protein encoded by this gene is a mitochondrial calcium-binding protein located in the luminal space of the terminal cisternae of the sarcoplasmic reticulum. The protein binds and putatively stores calcium ions. The protein is absent in patients with Duchenne and Becker types of muscular dystrophy.

Gene names and symbols associated with anti-Calsequestrin 1 (CASQ1) Antibodies

  • calsequestrin 1 (CASQ1) antibody
  • calsequestrin 1b (casq1b) antibody
  • Calsequestrin-1 (casq1) antibody
  • calsequestrin 1 (Casq1) antibody
  • calsequestrin 2 (CASQ2) antibody
  • CASQ antibody
  • CASQ1 antibody
  • CSQ antibody
  • CSQ-1 antibody
  • CSQ1 antibody
  • PDIB1 antibody
  • sCSQ antibody
  • zgc:154027 antibody

Protein level used designations for anti-Calsequestrin 1 (CASQ1) Antibodies

calsequestrin-1 , Calsequestrin-1 , calsequestrin, skeletal muscle isoform , aspartactin , laminin-binding protein , skeletal muscle calsequestrin 1 , calmitin , calmitine , Aspartactin , Laminin-binding protein , calsquestrin 1 , calsequestrin homologue , calsequestrin-2

GENE ID SPECIES
508394 Bos taurus
767757 Danio rerio
100195131 Salmo salar
12372 Mus musculus
100009095 Oryctolagus cuniculus
844 Homo sapiens
101118652 Ovis aries
686019 Rattus norvegicus
100156448 Sus scrofa
395198 Gallus gallus
608401 Canis lupus familiaris
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