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Cancer Susceptibility Candidate 3 (CASC3) ELISA Kits

The product of CASC3 is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). Additionally we are shipping Cancer Susceptibility Candidate 3 Antibodies (85) and Cancer Susceptibility Candidate 3 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CASC3 CASC3 22794 O15234
Anti-Mouse CASC3 CASC3 192160 Q8K3W3
Anti-Rat CASC3 CASC3 259170 Q8K3X0
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More ELISA Kits for Cancer Susceptibility Candidate 3 Interaction Partners

Human Cancer Susceptibility Candidate 3 (CASC3) interaction partners

  1. MLN51, alone or as part of the EJC, interacts directly with the pivotal eukaryotic translation initiation factor (show EIF2A ELISA Kits) eIF3 (show EIF3A ELISA Kits)

  2. MLN51 is a key factor in fibroblast-like synoviocyte hyperplasia of rheumatoid arthritis patients.

  3. data demonstrate that metastatic lymph node(MLN)51 protein associates with exon junction complex in the nucleus and remains stably associated with messenger RNA in the cytoplasm

  4. crystal structure of a tetrameric exon junction core complex containing the DEAD-box adenosine triphosphatase eukaryotic initiation factor 4AIII (show EIF4A3 ELISA Kits) bound to an ATP analog, MAGOH (show MAGOH ELISA Kits), Y14 (show RBM8A ELISA Kits), a fragment of MLN51, and a polyuracil mRNA mimic

  5. MLN51 is recruited into cytoplasmic aggregates known as stress granules (SGs (show FBN1 ELISA Kits)) together with the SG-resident proteins.

Mouse (Murine) Cancer Susceptibility Candidate 3 (CASC3) interaction partners

  1. data suggest that the mRNA transport machinery is conserved during evolution, and that mammalian Btz is an additional component of the dendritic ribonucleoprotein (show RBP31 ELISA Kits) particles in hippocampal neurons

Cancer Susceptibility Candidate 3 (CASC3) Antigen Profile

Antigen Summary

The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.

Gene names and symbols associated with CASC3

  • cancer susceptibility candidate 3 (CASC3) antibody
  • cancer susceptibility candidate 3 (casc3) antibody
  • metastatic lymph node 51 (mln51) antibody
  • cancer susceptibility candidate 3 (Casc3) antibody
  • protein CASC3 (casc3) antibody
  • barentsz antibody
  • Btz antibody
  • CASC3 antibody
  • Mln51 antibody
  • StMLN51 antibody
  • XlMLN51 antibody

Protein level used designations for CASC3

metastatic lymph node 51 , cancer susceptibility candidate 3 , Cancer susceptibility candidate gene 3 protein homolog , Metastatic lymph node protein 51 homolog , Protein MLN 51 homolog , protein CASC3 , MLN 51 , barentsz , cancer susceptibility candidate gene 3 protein , metastatic lymph node gene 51 protein , protein barentsz , Barentsz , MLN 51 homolog , cancer susceptibility candidate gene 3 protein homolog , mBtz , metastatic lymph node gene 51 protein homolog , barentsz protein , drMLN51 , metastatic lymph node protein 51 homolog , protein MLN 51 homolog

GENE ID SPECIES
454646 Pan troglodytes
480528 Canis lupus familiaris
503560 Xenopus (Silurana) tropicalis
699712 Macaca mulatta
100358381 Oryctolagus cuniculus
398567 Xenopus laevis
503559 Xenopus laevis
22794 Homo sapiens
192160 Mus musculus
259170 Rattus norvegicus
531673 Bos taurus
426135 Gallus gallus
403025 Danio rerio
100189566 Xenopus laevis
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