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Cancer/testis Antigen 2 Proteins (CTAG2)

CTAG2 encodes an autoimmunogenic tumor antigen that belongs to the ESO\\/LAGE family of cancer-testis antigens. Additionally we are shipping Cancer/testis Antigen 2 Antibodies (36) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CTAG2 30848 O75638
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Top Cancer/testis Antigen 2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human Un-conjugated Cancer/testis Antigen 2 (CTAG2) (AA 1-210), (full length) protein (His tag) Protein expressed in E.coli. 500 μg Log in to see 56 to 66 Days
$1,155.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CTAG2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Cancer/testis Antigen 2 (CTAG2) Interaction Partners

Human Cancer/testis Antigen 2 (CTAG2) interaction partners

  1. The tumor suppressor function of LSAMP is most likely exerted by reducing the proliferation rate of the tumor cells, possibly by indirectly upregulating one or more of the genes HES1, CTAG2 or KLF10.

  2. NYESO-1/LAGE-1s and PRAME (show PRAME Proteins) are targets for antigen specific T cells in chondrosarcoma following treatment with 5-Aza-2-deoxycitabine

  3. LAGE-1a and NY-ESO-1 (show CTAG1B Proteins) homology cannot be easily exploited in an anti-NY-ESO-1 (show CTAG1B Proteins) vaccine given the low frequency of protein expression detected by IHC or serum analysis.

  4. Spontaneous LAGE-1-specific CD4 (show CD4 Proteins)-positive T cells isolated from patients with advanced LAGE-1-positive/NY-ESO-1 (show CTAG1B Proteins)-positive melanoma are directed against three promiscuous and immunodominant epitopes.

  5. CD4+ T cell clones specific for alternatively translated tumor antigen CAMEL have been isolated from the peripheral blood of a melanoma patient; CAMEL(81-102) is described as a naturally processed epitope recognized and presented by HLA-DR11 and HLA-DR12.

  6. Data showed aberrant expression of NY-ESO-1 (show CTAG1B Proteins) and LAGE-1 by IHC/RT-PCR in a significant proportion of epithelial ovarian cancer patients.

  7. Data support the immunogenicity of NY-ESO-1 (show CTAG1B Proteins)/LAGE-1 ORF2 gene products and clearly demonstrate their capability to stimulate T-helper 1 type CD4 (show CD4 Proteins)+ T cells.

  8. LAGE-1 expression was more frequently found in squamous cell carcinoma than in adenocarcinoma.

  9. Isolation of CD4 (show CD4 Proteins)+ T cell clones from T cell cultures of two healthy donors leads to identification of four naturally processed HLA-DR-binding CAMEL epitopes, interesting peptides to investigate for future cancer immunotherapy.

  10. LAGE-1 expression was detected in esophageal cancer by cDNA RDA. LAGE-1 might have the potential to be a target antigen for anti-tumoral immunotherapy in esophageal cancers because of its tumor-specific expression similar to that of MAGE (show MAGEB10 Proteins)-A1.

Cancer/testis Antigen 2 (CTAG2) Protein Profile

Protein Summary

This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO\\/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID 10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with CTAG2

  • cancer/testis antigen 2 (CTAG2)
  • CAMEL protein
  • CT2 protein
  • CT6.2 protein
  • CT6.2a protein
  • CT6.2b protein
  • ESO2 protein
  • LAGE-1 protein
  • LAGE2B protein

Protein level used designations for CTAG2

CTL-recognized antigen on melanoma , LAGE-1a protein , autoimmunogenic cancer/testis antigen NY-ESO-2 , cancer/testis antigen 6.2 , cancer/testis antigen family 6, member 2a , cancer/testis antigen family 6, member 2b , l antigen family member 1

GENE ID SPECIES
30848 Homo sapiens
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