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Cannabinoid Receptor 1 Proteins (CNR1)

CNR1 encodes one of two cannabinoid receptors. Additionally we are shipping CNR1 Antibodies (136) and CNR1 Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNR1 1268 P21554
Rat CNR1 CNR1 25248 P20272
CNR1 12801 P47746
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Top CNR1 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details

CNR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
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More Proteins for Cannabinoid Receptor 1 (CNR1) Interaction Partners

Cow (Bovine) Cannabinoid Receptor 1 (CNR1) interaction partners

  1. Anandamide, through CB1 and TRPV1 (show TRPV1 Proteins) activation, is involved in sperm release from the oviductal reservoir.

Zebrafish Cannabinoid Receptor 1 (CNR1) interaction partners

  1. genetic or chemical inhibition of cannabinoid receptor (Cnr (show PCDHA1 Proteins)) activity disrupts liver development and metabolic function in zebrafish.

  2. CB1 function is required in the early embryo for axonal growth and fasciculation.

Human Cannabinoid Receptor 1 (CNR1) interaction partners

  1. Epistatic interaction between the 1359 G/A polymorphism of the CNR1 gene and the DRD2 (show DRD2 Proteins) gene polymorphisms may be associated with cannabis addiction phenotype in a Turkish population.

  2. in the group of all HD patients, a significantly higher incidence of GA genotype and lower incidence in GG genotype in the polymorphism rs806381s were revealed versus the control group (p = 0.04). It seems that polymorphisms of the CNR1 gene are not associated with uremic pruritus.

  3. Results suggest that CNR1 SNP genotype is associated with increased total cholesterol and Myocardial Infarction.

  4. this study presents the 2.8 A crystal structure of human CB1 in complex with AM6538, a stabilizing antagonist, synthesized and characterized for this structural study.

  5. Novel finding of the present study is the association of the mutant groups of CNR1 genotypes with lower levels of triglycerides and higher levels of HDL (show HSD11B1 Proteins)-cholesterol than the wild-type group.

  6. The present study reports an association of the G1359A and A1359A CNR1 genotypes with lower levels of triglycerides and higher levels of HDL (show HSD11B1 Proteins)-cholesterol in obese females.

  7. In the adult human ependyma, which usually shows central canal absence, CB1 may play a different role by modulating astrocyte functions

  8. Induction of apoptosis was mediated via CB1 as well as CB2 (show CNR2 Proteins), and expression of CB receptors was a prerequisite for therapy response in our models.

  9. CNR1 polymorphisms are not associated with obesity and metabolic disorders, including insulin (show INS Proteins) resistance, in PCOS women.

  10. data support an association between endocannabinoid system activity (cb1) and alcoholism.

Mouse (Murine) Cannabinoid Receptor 1 (CNR1) interaction partners

  1. CB1R expression contributes to the development of persistent mechanical hypersensitivity.

  2. Findings suggest a minor role for the CB2 (show CNR2 Proteins) receptor in the therapeutic effect of the cannabis-based medicine in AbetaPP/PS1 (show PSEN1 Proteins) transgenic mice, but also constitute evidence of a link between CB2 (show CNR2 Proteins) receptor and Abeta (show APP Proteins) processing

  3. Suggest that the CB1R is involved in auditory processing using CB1R knockout mice.

  4. CB1 activation negatively impacts GLP-1R (show GLP1R Proteins)-mediated insulin (show INS Proteins) secretion.

  5. Study showed that basolateral amygdala alpha2-adrenergic receptors may be involved in context- but not tone-dependent fear memory impairment induced by activation of CB1 receptors

  6. Adult female Cnr1 knockouts do not exhibit increased anxiety as in adult male Cnr1 knockouts; adult female ovariectomy does not increase anxiety-like behavior in Cnr1 knockouts; Cnr1 antagonism increases anxiety-like behavior in C57BL/6J mice

  7. Results provide clear evidence that the endocannabinoid system, through CB1 receptors, participates in the different stages of short- and long-term memory-related behavior

  8. CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice

  9. cannabidiol causes vasorelaxation of human mesenteric arteries via activation of cannabinoid receptor 1

  10. These results demonstrate that the CB1R-Ih pathway in the hippocampus is obligatory for the action of cannabinoids on long-term potentiation and spatial memory formation.

Pig (Porcine) Cannabinoid Receptor 1 (CNR1) interaction partners

  1. The endocannabinoid system in renal cells: regulation of sodium transport by CB1 receptors through distinct cell signaling pathways

Rhesus Monkey Cannabinoid Receptor 1 (CNR1) interaction partners

Xenopus laevis Cannabinoid Receptor 1 (CNR1) interaction partners

  1. CB1 functionality increased with development at both central and peripheral level.

CNR1 Protein Profile

Protein Summary

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

Gene names and symbols associated with Cannabinoid Receptor 1 Proteins (CNR1)

  • cannabinoid receptor 1 (brain) (CNR1)
  • cannabinoid receptor 1 (cnr1)
  • cannabinoid receptor 1 (LOC540382)
  • cannabinoid receptor 1 (brain) (Cnr1)
  • cannabinoid receptor 1 (brain) (cnr1)
  • CANN6 protein
  • CB-R protein
  • CB1 protein
  • CB1A protein
  • CB1K5 protein
  • CB1R protein
  • CNR protein
  • CNR1 protein
  • cnr1-A protein
  • LOC540382 protein
  • SKR6R protein

Protein level used designations for Cannabinoid Receptor 1 Proteins (CNR1)

cannabinoid receptor 1 (brain) , cannabinoid receptor (brain) , CB1R , cb1 , cannabinoid receptor 1 , cannabinoid receptor 1-like , central cannabinoid receptor , CB-R , CB1 , brain-type cannabinoid receptor , striatal cannabinoid receptor type 1 protein , cannabinoid 1 receptor , CB1 cannabinoid receptor , cannabinoid receptor CB-1 , cannabinoid receptor 1/CB1

GENE ID SPECIES
281087 Bos taurus
404209 Danio rerio
540382 Bos taurus
100065681 Equus caballus
100393865 Callithrix jacchus
100483374 Ailuropoda melanoleuca
1268 Homo sapiens
25248 Rattus norvegicus
12801 Mus musculus
481913 Canis lupus familiaris
493926 Felis catus
100169690 Cavia porcellus
100520160 Sus scrofa
100299449 Bos taurus
428633 Gallus gallus
101111639 Ovis aries
751607 Taeniopygia guttata
472066 Pan troglodytes
574142 Macaca mulatta
373759 Xenopus laevis
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