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Transcriptional repressor which may play a role in development of the central nervous system (CNS).. Additionally we are shipping CIC Antibodies (52) and and many more products for this protein.
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Our findings indicate that CIC is a critical regulator of BA homeostasis, and that its dysfunction might be associated with chronic liver disease and metabolic disorders.
mechanism by which constitutive reduction of Cic rescues Spinocerebellar ataxia (show USP14 ELISA Kits) type 1
Severe developmental bone phenotype in Cic deficient mice is reported.
Results describe the identification and characterization of a new gene, Cic, in both human and mouse genomes, that is implicated in granule cell development.
Report CIC genetic alterations in angiosarcomas.
With the advent of large-scale genome sequencing technology, molecular genetic alterations in CIC promoter have now been identified in the majority of oligodendrogliomas
miR (show MLXIP ELISA Kits)-93/miR (show MLXIP ELISA Kits)-106b/miR (show MLXIP ELISA Kits)-375-CIC-CRABP1 (show CRABP1 ELISA Kits) is a novel key regulatory axis in prostate cancer progression
CIC-rearranged sarcomas are distinct from Ewing sarcomas clinically, morphologically, and immunohistochemically, and they should be considered a separate entity rather than being grouped within the same family of tumors.
CIC mutations result in protein inactivation and poorer outcome in patients with a 1p19q codeleted glioma.
Our study showed for the first time a cooperative reduction in clonogenicity in cells co-expressing IDH1 (show IDH1 ELISA Kits)-R132H and mutant CIC proteins
Case Report: CIC-FOXO4 (show FOXO4 ELISA Kits) fusion sarcoma is a new type of Ewing-like sarcoma that has a specific genetic signature.
The distinct gene signature and immunoprofile of CIC-DUX4 sarcomas suggest a distinct pathogenesis from Ewing sarcoma.
We conclude that absent CIC and FUBP1 (show FUBP1 ELISA Kits) expressions are potential markers of shorter time to recurrence in oligodendroglial tumors.
Downregulation of CIC protein levels was not associated with ETV1 (show ETV1 ELISA Kits) or pMEK1/2 expression, KIT and PDGFRA (show PDGFRA ELISA Kits) mutations, copy number variations (CNV) of 19q13, and clinical factors.
Transcriptional repressor which may play a role in development of the central nervous system (CNS).
capicua homolog (Drosophila)
, capicua homolog
, protein capicua homolog