You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) Antibodies

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. Additionally we are shipping Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CAD 69719  
CAD 790 P27708
CAD 24240  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase Antibodies at antibodies-online.com

Showing 10 out of 97 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-CAD Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using CAD (Phospho-Thr456) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB CAD Antibody (Center)  western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CAD antibody detected the CAD protein (arrow). CAD Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAD Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB CAD Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAD Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. CAD Antibody (Center) western blot analysis in Jurkat cell line lysates (35µg/lane).This demonstrates the CAD antibody detected the CAD protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using CAD (Ab-456) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30μg whole cell lysate) A:293T whole cell lysate 5% SDS PAGE antibody diluted at 1:1500 WB Image CAD antibody [C2C3], C-term detects CAD protein by Western blot analysis. A. 30 µg C2C12 whole cell lysate/extract 5 % SDS-PAGE CAD antibody [C2C3], C-term , dilution: 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Fruit Fly Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

CAD Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,


Human , , , ,
,
,
, , , , ,
Rat (Rattus)


Top referenced anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase Antibodies

  1. Human Polyclonal CAD Primary Antibody for EIA, IHC (p) - ABIN950999 : Rossi, Serio, Stratta, Petruzzi, Schiazza, Mancini, Casacchia: Planum temporale asymmetry and thought disorder in schizophrenia. in Schizophrenia research 1994 (PubMed)
    Show all 4 references for ABIN950999

  2. Chicken Polyclonal CAD Primary Antibody for WB - ABIN2782488 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase Interaction Partners

Fruit Fly (Drosophila melanogaster) Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) interaction partners

  1. Using a systematic series of deletion mutants (all containing the intact DNA-binding homeodomain) we discovered that the C-terminal region of Caudal contributes to the preferential activation of the fushi tarazu (ftz (show NR5A1 Antibodies)) Caudal target gene.

  2. Bicoid acts through a 63 nt response element in the caudal 3' untranslated region that includes a single miR (show MYLIP Antibodies)-2 target site. Four predicted Bicoid splice isoforms are capable of caudal repression; all require the microRNA target for repression.

  3. Abdominal-B and caudal inhibit the formation of specific neuroblasts in the Drosophila tail region.

  4. Bicoid recruits Bin3 to the caudal 3' UTR (show UTS2R Antibodies).

  5. Bicoid associates with the 5'-cap-bound complex of caudal mRNA and represses translation.

  6. The caudal homeodomain protein activates Drosophila E2F (show E2F2 Antibodies) gene expression.

  7. Transcriptional activation of the Drosophila caudal homeobox (show PRRX1 Antibodies) gene by the DRE (show SUFUH Antibodies)-binding factor (DREF (show ZBED1 Antibodies)).

  8. In this study, we have identified the binding sites for bHLH-PAS (show PASK Antibodies) proteins, referred to as CNS midline element (CME), in the 5'-flanking region of the Drosophila caudal gene.

  9. study shows that the intestinal homeobox (show PRRX1 Antibodies) gene Caudal regulates the commensal-gut (show GUSB Antibodies) mutualism by repressing nuclear factor kappa B-dependent antimicrobial peptide (show cAMP Antibodies) genes

  10. Age- and oxidative-stress-related upregulation of the caudal gene is mediated by the NF-kappaB binding site located in the 5'-flanking region of the caudal gene.

Mouse (Murine) Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) interaction partners

  1. CAD functions as a necessary modulator of the hypertrophic response by regulating the mitogen-activated protein kinase (show MAPK1 Antibodies)-extracellular signal-regulated kinase 1/2 (show MAPK3 Antibodies) signaling pathway in the heart.

  2. the highest order of chromatin compaction observed in the later steps of caspase (show CASP3 Antibodies)-dependent apoptosis relies on DFF40/CAD (show DFFB Antibodies)-mediated DNA damage by generating 3'-OH ends in single-strand rather than double-strand DNA nicks/breaks

  3. results show that caspase 3 (show CASP3 Antibodies)/CAD promotes cell differentiation by directly modifying the DNA/nuclear microenvironment, which enhances the expression of critical regulatory genes

  4. Co-transfection of mouse DFF45 (show DFFA Antibodies)(-/-) fibroblasts with plasmids encoding human DFF40 (show DFFB Antibodies) and DFF45 (show DFFA Antibodies) reversed the apoptosis resistance normally observed in these cells

  5. The thymus of DNase II(-/-)CAD(-/-) embryos contained many foci carrying undigested DNA and the cellularity was severely reduced due to a block in T cell development.

  6. Interactions identified here between mouse liver histone H1 (show H1F0 Antibodies) carboxyl-terminal domain and DFF40/CAD (show DFFB Antibodies) target and activate linker DNA cleavage during the terminal stages of apoptosis.

  7. The results suggest that CAD protein may be preferentially degraded by the ubiquitin-proteasome system in the absence of its inhibitor (ICAD (show DFFA Antibodies)) to maintain protein quality control.

  8. A los of caspase-activated DNASE (show DFFB Antibodies) enhances tumorigenesis induced by a chemical carcinogen in a model of skin carcinogenesis in mice.

Zebrafish Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) interaction partners

  1. These findings suggest important posttranslational modifications requiring Cad as an unappreciated mechanism that regulates Notch/Vegf signaling during angiogenesis.

  2. an essential role for CAD in facilitating proliferation and differentiation events in a tissue-specific manner

Human Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) interaction partners

  1. Changes in glycosylation in caused by mutations in CAD.

  2. These results establish CAD as a downstream effector of Rheb (show RHEB Antibodies) and suggest a possible role of Rheb (show RHEB Antibodies) in regulating de novo pyrimidine nucleotide synthesis

  3. Recombinant aspartate carbamoyltransferase domain from the CAD enzyme complex forms homotrimers in solution.

  4. The results obtained indicate that mLST8 (show MLST8 Antibodies) bridges between CAD and mTOR (show FRAP1 Antibodies), and plays a role in the signaling mechanism where CAD is regulated in the mTOR (show FRAP1 Antibodies) pathway through the association with mLST8 (show MLST8 Antibodies)

  5. preliminary X-ray diffraction analysis of the dihydroorotase domain of human CAD

  6. findings show that in prostate tumor cells, CAD fosters androgen receptor (show AR Antibodies) translocation into the nucleus and stimulates its transcriptional activity; in radical prostatectomy specimens, CAD expression was not correlated with proliferation markers, but a higher CAD mRNA level was associated with local tumor extension and cancer relapse

  7. the cad gene is regulated by a nonclassical ERalpha (show ESR1 Antibodies)/Sp1 (show PSG1 Antibodies)-mediated pathway.

  8. Data show that PRMT5 can be found in association with hSWI/SNF complexes and is involved in regulating the expression of carbamoyl-phosphate synthase-aspartate carbamoyltransferase-dihydroorotase.

  9. the nuclear import of CAD appears to promote optimal cell growth

  10. cad gene expression is repressed by hypoxia-inducible factor-1alpha, which represents a functional link between hypoxia and cell-cycle arrest.

Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) Antigen Profile

Protein Summary

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.

Gene names and symbols associated with CAD

  • caudal (cad) antibody
  • carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (Cad) antibody
  • carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (cad) antibody
  • carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD) antibody
  • DNA fragmentation factor, beta polypeptide (caspase-activated DNase) (dffb) antibody
  • DNA fragmentation factor, beta subunit (Dffb) antibody
  • 38E.19 antibody
  • 40kDa antibody
  • 2410008J01Rik antibody
  • 5730477D02Rik antibody
  • anon-WO2004063362.83 antibody
  • AU018859 antibody
  • Cad antibody
  • cb456 antibody
  • cd antibody
  • CG1759 antibody
  • Cpad antibody
  • CPAN antibody
  • DFF40 antibody
  • Didff antibody
  • Dmel\\CG1759 antibody
  • S67 antibody
  • si:dkey-221h15.3 antibody
  • wu:fc30c12 antibody
  • wu:fc33d01 antibody
  • wu:fc67g02 antibody
  • xcad antibody

Protein level used designations for CAD

CG1759-PA , CG1759-PB , CG1759-PC , CG1759-PD , CG1759-PE , cad-PA , cad-PB , cad-PC , cad-PD , cad-PE , cadherin , CAD protein , carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase , carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase , CAD protein-like , CAD trifunctional protein , multifunctional protein CAD , carbamyl phosphatate synthetase 2 , CAD protein carbamylphosphate synthetase domain , dihydrorotate synthase , DNA fragmentation factor subunit beta , DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) , DFF-40 , DNA fragmentation factor 40 kDa subunit , DNA fragmentation factor, 40 kD, beta subunit , DNase inhibited by DNA fragmentation factor , caspase-activated DNase , caspase-activated deoxyribonuclease

GENE ID SPECIES
35341 Drosophila melanogaster
69719 Mus musculus
266992 Danio rerio
470338 Pan troglodytes
504261 Bos taurus
699460 Macaca mulatta
100055366 Equus caballus
100125119 Xenopus (Silurana) tropicalis
100352236 Oryctolagus cuniculus
100405052 Callithrix jacchus
100444071 Pongo abelii
790 Homo sapiens
428659 Gallus gallus
483009 Canis lupus familiaris
24240 Rattus norvegicus
101843763 Mesocricetus auratus
373130 Danio rerio
13368 Mus musculus
Selected quality suppliers for anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) Antibodies
Did you look for something else?