You are viewing an incomplete version of our website. Please click to reload the website as full version.

Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) ELISA Kits

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. Additionally we are shipping Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase Antibodies (98) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse CAD CAD 69719  
CAD 790 P27708
Anti-Rat CAD CAD 24240  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase ELISA Kits at antibodies-online.com

Showing 1 out of 2 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.052 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details

More ELISA Kits for Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase Interaction Partners

Fruit Fly (Drosophila melanogaster) Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) interaction partners

  1. Using a systematic series of deletion mutants (all containing the intact DNA-binding homeodomain) we discovered that the C-terminal region of Caudal contributes to the preferential activation of the fushi tarazu (ftz (show NR5A1 ELISA Kits)) Caudal target gene.

  2. Bicoid acts through a 63 nt response element in the caudal 3' untranslated region that includes a single miR (show MYLIP ELISA Kits)-2 target site. Four predicted Bicoid splice isoforms are capable of caudal repression; all require the microRNA target for repression.

  3. Abdominal-B and caudal inhibit the formation of specific neuroblasts in the Drosophila tail region.

  4. Bicoid recruits Bin3 to the caudal 3' UTR (show UTS2R ELISA Kits).

  5. Bicoid associates with the 5'-cap-bound complex of caudal mRNA and represses translation.

  6. The caudal homeodomain protein activates Drosophila E2F (show E2F2 ELISA Kits) gene expression.

  7. Transcriptional activation of the Drosophila caudal homeobox gene by the DRE-binding factor (DREF).

  8. In this study, we have identified the binding sites for bHLH-PAS (show PASK ELISA Kits) proteins, referred to as CNS midline element (CME), in the 5'-flanking region of the Drosophila caudal gene.

  9. study shows that the intestinal homeobox (show PRRX1 ELISA Kits) gene Caudal regulates the commensal-gut (show GUSB ELISA Kits) mutualism by repressing nuclear factor kappa B-dependent antimicrobial peptide (show cAMP ELISA Kits) genes

  10. Age- and oxidative-stress-related upregulation of the caudal gene is mediated by the NF-kappaB binding site located in the 5'-flanking region of the caudal gene.

Mouse (Murine) Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) interaction partners

  1. CAD functions as a necessary modulator of the hypertrophic response by regulating the mitogen-activated protein kinase (show MAPK1 ELISA Kits)-extracellular signal-regulated kinase 1/2 (show MAPK3 ELISA Kits) signaling pathway in the heart.

  2. the highest order of chromatin compaction observed in the later steps of caspase (show CASP3 ELISA Kits)-dependent apoptosis relies on DFF40/CAD (show DFFB ELISA Kits)-mediated DNA damage by generating 3'-OH ends in single-strand rather than double-strand DNA nicks/breaks

  3. results show that caspase 3 (show CASP3 ELISA Kits)/CAD promotes cell differentiation by directly modifying the DNA/nuclear microenvironment, which enhances the expression of critical regulatory genes

  4. Co-transfection of mouse DFF45 (show DFFA ELISA Kits)(-/-) fibroblasts with plasmids encoding human DFF40 (show DFFB ELISA Kits) and DFF45 (show DFFA ELISA Kits) reversed the apoptosis resistance normally observed in these cells

  5. The thymus of DNase II(-/-)CAD(-/-) embryos contained many foci carrying undigested DNA and the cellularity was severely reduced due to a block in T cell development.

  6. Interactions identified here between mouse liver histone H1 (show H1F0 ELISA Kits) carboxyl-terminal domain and DFF40/CAD (show DFFB ELISA Kits) target and activate linker DNA cleavage during the terminal stages of apoptosis.

  7. The results suggest that CAD protein may be preferentially degraded by the ubiquitin-proteasome system in the absence of its inhibitor (ICAD (show DFFA ELISA Kits)) to maintain protein quality control.

  8. A los of caspase-activated DNASE (show DFFB ELISA Kits) enhances tumorigenesis induced by a chemical carcinogen in a model of skin carcinogenesis in mice.

Zebrafish Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) interaction partners

  1. These findings suggest important posttranslational modifications requiring Cad as an unappreciated mechanism that regulates Notch/Vegf signaling during angiogenesis.

  2. an essential role for CAD in facilitating proliferation and differentiation events in a tissue-specific manner

Human Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) interaction partners

  1. Changes in glycosylation in caused by mutations in CAD.

  2. These results establish CAD as a downstream effector of Rheb (show RHEB ELISA Kits) and suggest a possible role of Rheb (show RHEB ELISA Kits) in regulating de novo pyrimidine nucleotide synthesis

  3. Recombinant aspartate carbamoyltransferase domain from the CAD enzyme complex forms homotrimers in solution.

  4. The results obtained indicate that mLST8 (show MLST8 ELISA Kits) bridges between CAD and mTOR (show FRAP1 ELISA Kits), and plays a role in the signaling mechanism where CAD is regulated in the mTOR (show FRAP1 ELISA Kits) pathway through the association with mLST8 (show MLST8 ELISA Kits)

  5. preliminary X-ray diffraction analysis of the dihydroorotase domain of human CAD

  6. findings show that in prostate tumor cells, CAD fosters androgen receptor (show AR ELISA Kits) translocation into the nucleus and stimulates its transcriptional activity; in radical prostatectomy specimens, CAD expression was not correlated with proliferation markers, but a higher CAD mRNA level was associated with local tumor extension and cancer relapse

  7. the cad gene is regulated by a nonclassical ERalpha (show ESR1 ELISA Kits)/Sp1 (show PSG1 ELISA Kits)-mediated pathway.

  8. Data show that PRMT5 can be found in association with hSWI/SNF complexes and is involved in regulating the expression of carbamoyl-phosphate synthase-aspartate carbamoyltransferase-dihydroorotase.

  9. the nuclear import of CAD appears to promote optimal cell growth

  10. cad gene expression is repressed by hypoxia-inducible factor-1alpha, which represents a functional link between hypoxia and cell-cycle arrest.

Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) Antigen Profile

Antigen Summary

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.

Gene names and symbols associated with CAD

  • caudal (cad) antibody
  • carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (Cad) antibody
  • carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (cad) antibody
  • carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD) antibody
  • DNA fragmentation factor, beta polypeptide (caspase-activated DNase) (dffb) antibody
  • DNA fragmentation factor, beta subunit (Dffb) antibody
  • 38E.19 antibody
  • 40kDa antibody
  • 2410008J01Rik antibody
  • 5730477D02Rik antibody
  • anon-WO2004063362.83 antibody
  • AU018859 antibody
  • Cad antibody
  • cb456 antibody
  • cd antibody
  • CG1759 antibody
  • Cpad antibody
  • CPAN antibody
  • DFF40 antibody
  • Didff antibody
  • Dmel\\CG1759 antibody
  • S67 antibody
  • si:dkey-221h15.3 antibody
  • wu:fc30c12 antibody
  • wu:fc33d01 antibody
  • wu:fc67g02 antibody
  • xcad antibody

Protein level used designations for CAD

CG1759-PA , CG1759-PB , CG1759-PC , CG1759-PD , CG1759-PE , cad-PA , cad-PB , cad-PC , cad-PD , cad-PE , cadherin , CAD protein , carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase , carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase , CAD protein-like , CAD trifunctional protein , multifunctional protein CAD , carbamyl phosphatate synthetase 2 , CAD protein carbamylphosphate synthetase domain , dihydrorotate synthase , DNA fragmentation factor subunit beta , DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) , DFF-40 , DNA fragmentation factor 40 kDa subunit , DNA fragmentation factor, 40 kD, beta subunit , DNase inhibited by DNA fragmentation factor , caspase-activated DNase , caspase-activated deoxyribonuclease

GENE ID SPECIES
35341 Drosophila melanogaster
69719 Mus musculus
266992 Danio rerio
470338 Pan troglodytes
504261 Bos taurus
699460 Macaca mulatta
100055366 Equus caballus
100125119 Xenopus (Silurana) tropicalis
100352236 Oryctolagus cuniculus
100405052 Callithrix jacchus
100444071 Pongo abelii
790 Homo sapiens
428659 Gallus gallus
483009 Canis lupus familiaris
24240 Rattus norvegicus
101843763 Mesocricetus auratus
373130 Danio rerio
13368 Mus musculus
Selected quality suppliers for Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) ELISA Kits
Did you look for something else?