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Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Proteins (CHST14)

CHST14 encodes a member of the HNK-1 family of sulfotransferases. Additionally we are shipping Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Antibodies (29) and Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHST14 113189 Q8NCH0
CHST14 72136 Q80V53
Rat CHST14 CHST14 691394  
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Top Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

CHST14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14) Interaction Partners

Human Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14) interaction partners

  1. CHST14 gene mutations are associated with musculocontractural type of Ehlers-Danlos syndrome.

  2. We report on the detailed clinical characterization of two sisters with musculocontractural Ehlers-Danlos syndrome caused by a homozygous mutation in the CHST14 gene.

  3. Loss of dermatan-4-sulfotransferase 1 (D4ST1/CHST14) function represents the first dermatan sulfate biosynthesis defect, "dermatan sulfate-deficient adducted thumb-clubfoot syndrome".

  4. Musculocontractural Ehlers-Danlos Syndrome (former EDS type VIB (show SEMA6B Proteins)) and adducted thumb clubfoot syndrome (ATCS) represent a single clinical entity caused by mutations in the dermatan-4-sulfotransferase 1 encoding CHST14 gene.

  5. A homozygous CHST14 (carbohydrate sulfotransferase 14) mutation in the two familial cases and compound heterozygous mutations in four sporadic cases of Ehlers-Danlos syndrome, were identified.

  6. D4ST-1 is a key enzyme and is indispensable in the formation of important functional domains in dermatan sulfate and cannot be compensated by other 4-O-sulfotransferases

  7. dermatan-4-sulfotransferase 1 has a role in adducted thumb-clubfoot syndrome

  8. human D4ST-1, C4ST-1 (show CHST11 Proteins), and S4ST-2 have differential roles in dermatan sulfate biosynthesis

  9. D4ST-1 is encoded by a single exon located on human chromosome 15q14; type II membrane protein of 376 amino acids with a 43-amino acid cytoplasmic domain and a 316-amino acid luminal domain containing two potential N-linked glycosylation sites

Mouse (Murine) Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14) interaction partners

  1. Deficiency for Chst14 results in decreased neurogenesis and diminished proliferation of neural stem cells.

  2. analysis of the three CS sulfotransferases in the developing neocortex: uronyl 2-O-sulfotransferase (UST), N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (4,6-ST) and dermatan 4-O-sulfotransferase-1 (D4-ST)

Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14) Protein Profile

Protein Summary

This gene encodes a member of the HNK-1 family of sulfotransferases. The encoded protein transfers sulfate to the C-4 hydroxyl of N-acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb-clubfoot syndrome.

Gene names and symbols associated with CHST14

  • carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 (CHST14)
  • carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 (Chst14)
  • carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 (chst14)
  • 2600016L03Rik protein
  • ATCS protein
  • D4ST-1 protein
  • d4st1 protein
  • HNK1ST protein
  • MGC136487 protein
  • wu:fc04a01 protein
  • zgc:136487 protein

Protein level used designations for CHST14

carbohydrate sulfotransferase 14 , dermatan 4 sulfotransferase 1 , dermatan 4-sulfotransferase 1 , dermatan-4-sulfotransferase-1 , D4ST-1 , zD4ST-1

GENE ID SPECIES
113189 Homo sapiens
511245 Bos taurus
72136 Mus musculus
691394 Rattus norvegicus
404732 Danio rerio
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