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anti-Carbohydrate Antigen 15-3 (CA15-3) Antibodies

CA15-3 encodes a membrane-bound protein that is a member of the mucin family.

list all antibodies Gene Name GeneID UniProt
Anti-Human CA15-3 CA15-3 4582 P15941
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More Antibodies against Carbohydrate Antigen 15-3 Interaction Partners

Human Carbohydrate Antigen 15-3 (CA15-3) interaction partners

  1. identified this type of MUC1 (show MUC1 Antibodies) mutation in 9.5 % of families from an ADTKD Italian cohort; larger studies are needed to better define the criteria for genetic testing for this type of mutation

  2. MUC1 (show MUC1 Antibodies) was expressed in 238 (64 %) tumors and had no impact on outcome

  3. that, in adenocarcinomas and borderline ovarian tumors, the major carriers of SLe(a) and SLe(x) are MUC16 (show MUC16 Antibodies) and/or MUC1 (show MUC1 Antibodies) (100 and 92 % for SLe(a)

  4. analysis of LGALS3, PHB2, MUC1, and GK2 expression with CA15-3 in early-stage breast cancer

  5. High Muc1 (show MUC1 Antibodies) expression is associated with lung adenocarcinoma.

  6. Overexpression of MUC1 (show MUC1 Antibodies) is associated with Breast Cancer Micrometastasis.

  7. we evaluated the clinical performance of LOCItrade mark-based tumor marker assays CEA (show CEACAM5 Antibodies), CA19-9, CA15-3, CA125 (show MUC16 Antibodies) and AFP (show AFP Antibodies) in patients with gastrointestinal cancer and demonstrated their high diagnostic power

  8. These data suggest that imbalance of IL-22 (show IL22 Antibodies)/IL-22R1 signaling regulates the pathogenesis of chronic rhinosinusitis with nasal polyps, including local eosinophilia, via alteration of MUC1 (show MUC1 Antibodies) expression.

  9. This review aims to encompass a detailed characterization of MUC1 (show MUC1 Antibodies) role in carcinogenesis, highlighting recent findings in cell differentiation and uncovering new evidences of MUC1 (show MUC1 Antibodies) isoforms involvement in malignant phenotype. [Review]

  10. The reverse polarity of colorectal micropapillary carcinomas is sometimes better visualised by immunostains other than EMA/MUC1 (show MUC1 Antibodies).

Carbohydrate Antigen 15-3 (CA15-3) Antigen Profile

Protein Summary

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with CA15-3

  • mucin 1 (MUC1) antibody
  • mucin 1, cell surface associated (MUC1) antibody
  • CA 15-3 antibody
  • CD227 antibody
  • EMA antibody
  • H23AG antibody
  • KL-6 antibody
  • MAM6 antibody
  • MCKD1 antibody
  • MUC-1 antibody
  • MUC-1/SEC antibody
  • MUC-1/X antibody
  • MUC1 antibody
  • MUC1/ZD antibody
  • PEM antibody
  • PEMT antibody
  • PUM antibody

Protein level used designations for CA15-3

mucin 1 , DF3 antigen , H23 antigen , breast carcinoma-associated antigen DF3 , cancer antigen 15-3 , carcinoma-associated mucin , episialin , krebs von den Lungen-6 , mucin 1, transmembrane , mucin-1 , peanut-reactive urinary mucin , polymorphic epithelial mucin , tumor associated epithelial mucin , tumor-associated epithelial membrane antigen , tumor-associated mucin

100294522 Felis catus
4582 Homo sapiens
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