anti-Carbohydrate Antigen 15-3 (CA15-3) Antibodies

CA15-3 encodes a membrane-bound protein that is a member of the mucin family.

list all antibodies Gene Name GeneID UniProt
Anti-Human CA15-3 CA15-3 4582 P15941
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

More Antibodies against Carbohydrate Antigen 15-3 Interaction Partners

Human Carbohydrate Antigen 15-3 (CA15-3) interaction partners

  1. The MUC1 (show MUC1 Antibodies) oncoprotein was identified as the critical driver of (extracellular vesicle) EV-mediated myeloid-derived suppressor cells expansion in AML (show RUNX1 Antibodies). microRNA miR34a acts as the regulatory mechanism by which MUC1 (show MUC1 Antibodies) drives c-myc (show MYC Antibodies) expression in AML (show RUNX1 Antibodies) cells and EVs.

  2. immunoexpression of different epitopes (external and cytoplasmic) of MUC1 (show MUC1 Antibodies) expression are altered in tubes with ectopic pregnancy compared with normal tubes, suggesting an association to explain its etiology

  3. Data show that triple-negative breast cancer (TNBC) patients with pre-therapeutic serum high levels of both carcinoembryonic antigen (CEA (show CEACAM5 Antibodies)) and cancer antigen 15-3 (CA15-3) had shorter overall survival (OS) and disease-free survival (DFS (show FST Antibodies)) rates than those in the low-level groups.

  4. MUC1 (show MUC1 Antibodies) expression correlates with tumor metastatic recurrence in postoperative esophageal squamous cell cancer patients

  5. Differences in the apparent expression levels of CEA (show CEACAM5 Antibodies), CA153 and CA125 (show MUC16 Antibodies) in patients with nipple discharge and healthy persons were validated.

  6. Detection of MUC1 (show MUC1 Antibodies) and HS3ST2 (show HS3ST2 Antibodies) promoter methylation status appears to be useful molecular markers for assessing the progressive state of the disease and could be helpful in discriminating breast cancer molecular subtypes. These results validate the methylation-based microarray analysis, thus trust their output in the future.

  7. Data show that added synthetic long peptides derived from widely expressed oncoproteins MUC1 (show MUC1 Antibodies) and HER2/neu (show ERBB2 Antibodies) were reliably presented to CD4 (show CD4 Antibodies)+ T-cells and cross-presented to CD8 (show CD8A Antibodies)+ T-cells.

  8. MUC1 (show MUC1 Antibodies) is aberrantly overexpressed on the entire tumor cell surface of most human cancers; MUC1 (show MUC1 Antibodies) induces tamoxifen resistance in estrogen receptor (show ESR1 Antibodies)-positive breast cancer

  9. MUC1 (show MUC1 Antibodies) protein expression was associated with adverse pathological features, although it was not an independent predictor of outcome after radical prostatectomy.

  10. Findings provide evidence that rs4072037 MUC1 (show MUC1 Antibodies) does not have a significant impact on the pathogenesis or prognosis of lung adenocarcinoma (ADC (show ADC Antibodies)), whereas KL-6 serum levels, which might reflecting the molecular length of MUC1 (show MUC1 Antibodies), are significantly associated with lung ADC (show ADC Antibodies).

Carbohydrate Antigen 15-3 (CA15-3) Antigen Profile

Protein Summary

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with CA15-3

  • mucin 1 (MUC1) antibody
  • mucin 1, cell surface associated (MUC1) antibody
  • CA 15-3 antibody
  • CD227 antibody
  • EMA antibody
  • H23AG antibody
  • KL-6 antibody
  • MAM6 antibody
  • MCKD1 antibody
  • MUC-1 antibody
  • MUC-1/SEC antibody
  • MUC-1/X antibody
  • MUC1 antibody
  • MUC1/ZD antibody
  • PEM antibody
  • PEMT antibody
  • PUM antibody

Protein level used designations for CA15-3

mucin 1 , DF3 antigen , H23 antigen , breast carcinoma-associated antigen DF3 , cancer antigen 15-3 , carcinoma-associated mucin , episialin , krebs von den Lungen-6 , mucin 1, transmembrane , mucin-1 , peanut-reactive urinary mucin , polymorphic epithelial mucin , tumor associated epithelial mucin , tumor-associated epithelial membrane antigen , tumor-associated mucin

GENE ID SPECIES
100294522 Felis catus
4582 Homo sapiens
Did you look for something else?