Carbohydrate Antigen 15-3 (CA15-3) ELISA Kits

CA15-3 encodes a membrane-bound protein that is a member of the mucin family.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CA15-3 CA15-3 4582 P15941
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More ELISA Kits for Carbohydrate Antigen 15-3 Interaction Partners

Human Carbohydrate Antigen 15-3 (CA15-3) interaction partners

  1. MUC1 (show MUC1 ELISA Kits)-C is of functional importance to induction of DNMT1 (show DNMT1 ELISA Kits) and DNMT3b (show DNMT3B ELISA Kits) and, in turn, changes in DNA methylation (show HELLS ELISA Kits) patterns in cancer cells.

  2. The MUC1 (show MUC1 ELISA Kits) oncoprotein was identified as the critical driver of (extracellular vesicle) EV-mediated myeloid-derived suppressor cells expansion in AML (show RUNX1 ELISA Kits). microRNA miR34a acts as the regulatory mechanism by which MUC1 (show MUC1 ELISA Kits) drives c-myc (show MYC ELISA Kits) expression in AML (show RUNX1 ELISA Kits) cells and EVs.

  3. immunoexpression of different epitopes (external and cytoplasmic) of MUC1 (show MUC1 ELISA Kits) expression are altered in tubes with ectopic pregnancy compared with normal tubes, suggesting an association to explain its etiology

  4. Data show that triple-negative breast cancer (TNBC) patients with pre-therapeutic serum high levels of both carcinoembryonic antigen (CEA (show CEACAM5 ELISA Kits)) and cancer antigen 15-3 (CA15-3) had shorter overall survival (OS) and disease-free survival (DFS (show FST ELISA Kits)) rates than those in the low-level groups.

  5. MUC1 (show MUC1 ELISA Kits) expression correlates with tumor metastatic recurrence in postoperative esophageal squamous cell cancer patients

  6. Differences in the apparent expression levels of CEA (show CEACAM5 ELISA Kits), CA153 and CA125 (show MUC16 ELISA Kits) in patients with nipple discharge and healthy persons were validated.

  7. Detection of MUC1 (show MUC1 ELISA Kits) and HS3ST2 (show HS3ST2 ELISA Kits) promoter methylation status appears to be useful molecular markers for assessing the progressive state of the disease and could be helpful in discriminating breast cancer molecular subtypes. These results validate the methylation-based microarray analysis, thus trust their output in the future.

  8. Data show that added synthetic long peptides derived from widely expressed oncoproteins MUC1 (show MUC1 ELISA Kits) and HER2/neu (show ERBB2 ELISA Kits) were reliably presented to CD4 (show CD4 ELISA Kits)+ T-cells and cross-presented to CD8 (show CD8A ELISA Kits)+ T-cells.

  9. MUC1 (show MUC1 ELISA Kits) is aberrantly overexpressed on the entire tumor cell surface of most human cancers; MUC1 (show MUC1 ELISA Kits) induces tamoxifen resistance in estrogen receptor (show ESR1 ELISA Kits)-positive breast cancer

  10. MUC1 (show MUC1 ELISA Kits) protein expression was associated with adverse pathological features, although it was not an independent predictor of outcome after radical prostatectomy.

Carbohydrate Antigen 15-3 (CA15-3) Antigen Profile

Antigen Summary

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with CA15-3

  • mucin 1 (MUC1) antibody
  • mucin 1, cell surface associated (MUC1) antibody
  • CA 15-3 antibody
  • CD227 antibody
  • EMA antibody
  • H23AG antibody
  • KL-6 antibody
  • MAM6 antibody
  • MCKD1 antibody
  • MUC-1 antibody
  • MUC-1/SEC antibody
  • MUC-1/X antibody
  • MUC1 antibody
  • MUC1/ZD antibody
  • PEM antibody
  • PEMT antibody
  • PUM antibody

Protein level used designations for CA15-3

mucin 1 , DF3 antigen , H23 antigen , breast carcinoma-associated antigen DF3 , cancer antigen 15-3 , carcinoma-associated mucin , episialin , krebs von den Lungen-6 , mucin 1, transmembrane , mucin-1 , peanut-reactive urinary mucin , polymorphic epithelial mucin , tumor associated epithelial mucin , tumor-associated epithelial membrane antigen , tumor-associated mucin

GENE ID SPECIES
100294522 Felis catus
4582 Homo sapiens
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