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Carbonic Anhydrase II Proteins (CA2)

CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Additionally we are shipping Carbonic Anhydrase II Antibodies (211) and Carbonic Anhydrase II Kits (52) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CA2 12349 P00920
CA2 54231 P27139
CA2 760 P00918
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Top Carbonic Anhydrase II Proteins at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$367.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg Log in to see 7 to 9 Days
$467.86
Details
HOST_HEK-293 Human His tag 50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$739.20
Details

CA2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Rat (Rattus) , ,

Human , , , ,
, ,

Top referenced Carbonic Anhydrase II Proteins

  1. Mouse (Murine) CA2 Protein expressed in Escherichia coli (E. coli) - ABIN2008154 : Cox, Hunt, Compher, Fierke, Christianson: Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II. in Biochemistry 2000 (PubMed)
    Show all 3 references for ABIN2008154

  2. Human CA2 Protein expressed in Escherichia coli (E. coli) - ABIN2002929 : Briganti, Mangani, Scozzafava, Vernaglione, Supuran: Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction? in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 1999 (PubMed)
    Show all 3 references for ABIN2002929

  3. Human CA2 Protein expressed in Escherichia coli (E. coli) - ABIN667740 : Hu, Roth, Skaggs, Venta, Tashian, Guibaud, Sly: A splice junction mutation in intron 2 of the carbonic anhydrase II gene of osteopetrosis patients from Arabic countries. in Human mutation 1993 (PubMed)
    Show all 2 references for ABIN667740

  4. Human CA2 Protein expressed in HEK-293 Cells - ABIN2180674 : Yu, Price, Badger: A Mutant Isolated from the Cyanobacterium Synechococcus PCC7942 Is Unable to Adapt to Low Inorganic Carbon Conditions. in Plant physiology 2002 (PubMed)
    Show all 2 references for ABIN2180674

More Proteins for Carbonic Anhydrase II (CA2) Interaction Partners

Xenopus laevis Carbonic Anhydrase II (CA2) interaction partners

  1. a bicarbonate transport metabolon proposed for the interaction between CAII and NBCe1 (show SLC4A4 Proteins) does not work at least in Xenopus oocytes

Arabidopsis thaliana Carbonic Anhydrase II (CA2) interaction partners

  1. CA2 is an integral membrane protein localized on the matrix-exposed side of the membrane arm of complex I.

Mouse (Murine) Carbonic Anhydrase II (CA2) interaction partners

  1. two CA isoforms, CAII and CAIV (show CA4 Proteins), are distributed along the epididymal epithelium and appear with the onset of puberty

  2. The Na(+)-Cl(-) cotransporter NCC (show SLC12A3 Proteins) /Carbonic anhydrase II double Knockout mice displayed significant downregulation of pendrin (show SLC26A4 Proteins), along with polyuria and salt wasting.

  3. CA2 expression is strongly regulated by intracellular pH and by cAMP, suggesting a role for soluble adenylyl cyclase (show ADCY10 Proteins)

  4. sclerostin (show SOST Proteins) upregulated osteocyte expression of carbonic anhydrase 2.

  5. During inner ear development, transcripts of four cytosolic isozymes (Car1 (show CA1 Proteins), Car2, Car3 (show CA3 Proteins), and Car13 (show CA13 Proteins)), two membrane-bound isozymes (Car12 and Car14 (show CA14 Proteins)), and two CA-related proteins (Car8 (show CA8 Proteins) and Car11 (show CA11 Proteins)) were expressed at higher levels than other isozymes.

  6. Car2, Car3, Car7, and Car15 mRNAs were barely within the detection limits in the mouse harderian gland.

  7. Suggest that during amelogenesis CAII controls the differentiation of ameloblasts. Regulation of intracellular pH, followed by activation of the JNK (show MAPK8 Proteins) signaling pathway, may be responsible for the effects of CAII on ameloblasts.

  8. Both kNBC1 (show SLC4A4 Proteins)-Asp (show C3 Proteins)(986) and kNBC1 (show SLC4A4 Proteins)-Asp (show C3 Proteins)(988), but not kNBC1 (show SLC4A4 Proteins)-Asp (show C3 Proteins)(989), are required for the phosphorylation-induced shift in stoichiometry. A homologous motif (D887ADD) in the carboxy-terminus of the anion exchanger AE1 (show SLC4A1 Proteins) binds to carbonic anhydrase II.

  9. Results show that the stimulatory effect of the duodenal secretagogue prostaglandin E2 completely depends on carbonic anhydrase II.

  10. Altered expression of Car2 and Ncam1 (show NCAM1 Proteins) is a downstream event in placental hyperplasia.

Human Carbonic Anhydrase II (CA2) interaction partners

  1. identified 2 novel mutations in 2 Chinese families with CAII deficiency syndrome; a nonsense mutation in exon 4 in both families; a splice mutation at the splice donor site of intron 3 in 1 family; the splice-site mutation causes exon 3 skipping in patient's mRNA resulting in an in-frame deletion and a novel premature stop codon

  2. binding of dorzolamide to bovine and human carbonic anhydrase II

  3. Using paramagnetic NMR techniques and X-ray absorption spectroscopy we identified an N-terminal Cu(2+) binding site in carbonic anhydrase II.

  4. CAII increases water conductance through AQP1 by a physical interaction between the two proteins.

  5. carbonic anhydrase catalytic cycle for natural and promiscuous substrates

  6. Suggest an association between CAII and NHE3 (show SLC9A3 Proteins) that alters the transporter's activity in kidney cell line.

  7. The down-regulation of CA II expression was observed in gastric cancer and may serve as an independent prognostic factor for the overall survival of gastric cancer patients.

  8. Binding of cyanate to CA II is directly to the zinc, displacing the zinc-bound solvent molecule, and not in a site that overlaps with the CO2 substrate-binding site.

  9. Carbonic anhydrase II may play a critical role in neuroendocrine tumor lung tumor growth

  10. the pHi of cells with low CAi activity was less responsive to pCO2 fluctuations. Such low pass filtering would "buffer" cancer cell pHi from non-steady-state extracellular pCO2. Thus

Cow (Bovine) Carbonic Anhydrase II (CA2) interaction partners

  1. binding of dorzolamide to bovine and human carbonic anhydrase II

  2. Increasing the number and distribution of surface acidic groups of CAII is sufficient to function in high-salt environments.

  3. Folding analysis of the zinc protein, carbonic anhydrase 2 was performed using electrospray ionization ion mobility spectrometry coupled with collision-induced dissociation.

  4. Intense positive staining for CA-II was found in luminal duct cells and for the first time also inside the duct lumen, clearly demonstrating the expression and secretion of salivary CA-II in bovine parotid glands.

  5. structure refined to 1.95 A resolution; has a C-terminal knot structure; contains one zinc ion in the active site coordinated to 3 his and 1 water molecule; structure reveals a probable alternative proton-wire pathway that differs from that of HCA II.

  6. novel series of mono- and bis (show BAG3 Proteins)- benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II

  7. catalytic activity of CAII affects the SNAT3 (show SLC38A3 Proteins) conductance, but presumably not by increasing the local H+ buffer capacity

  8. kinetics of refolding of carbonic anhydrase II following transfer from a buffer containing 5 m guanidinium chloride to a buffer containing 0.5 m guanidinium chloride

  9. The urea-induced unfolding of bovine carbonic anhydrase II, BCA (show BLNK Proteins) II, is characterized by a combination of high-resolution NMR, circular dichroism spectroscopy and small angle X-ray scattering.

  10. Carbonic anhydrase II (BCA (show BLNK Proteins) II) when incubated in mildly denaturing conditions showed that the partially unfolded conformers assemble together and form ordered amyloid aggregates.

Carbonic Anhydrase II (CA2) Protein Profile

Protein Summary

CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.

Gene names and symbols associated with Carbonic Anhydrase II Proteins (CA2)

  • Carbonic anhydrase 2 (CAH2)
  • carbonic anhydrase 2 (ca2)
  • carbonic anhydrase 2 (CA2)
  • carbonic anhydrase 2 (HCAG_04637)
  • carbonic anhydrase 2 (LOC100135827)
  • carbonic anhydrase 1-like (LOC100635510)
  • carbonic anhydrase 2 (Car2)
  • carbonic anhydrase II (CA2)
  • carbonic anhydrase II (Ca2)
  • carbonic anhydrase, alpha type, periplasmic (CAH2)
  • AI131712 protein
  • BETA CA2 protein
  • BETA CARBONIC ANHYDRASE 2 protein
  • CA-2 protein
  • CA-II protein
  • Ca2 protein
  • CA18 protein
  • CAC protein
  • ca ii protein
  • CAII protein
  • Car-2 protein
  • Car2 protein
  • CAR3 protein
  • carbonic anhydrase 2 protein
  • CARBONIC ANHYDRASE 18 protein
  • CG6906 protein
  • CT21171 protein
  • Dmel\\CG6906 protein
  • LOC100135827 protein
  • Ltw-5 protein
  • Lvtw-5 protein
  • T9L3.40 protein
  • T9L3_40 protein

Protein level used designations for Carbonic Anhydrase II Proteins (CA2)

CAH2-PA , CAH2-PB , CG6906-PA , CG6906-PB , carbonic anhydrase 2 , carbonic anhydrase II , carbonic anhydrase type 2 , erythrocyte carbonic anhydrase , CA II , CA-II , carbonate dehydratase II , carbonic anhydrase B , carbonic anhydrase C , carbonic dehydratase

GENE ID SPECIES
39390 Drosophila melanogaster
379772 Xenopus laevis
548446 Xenopus (Silurana) tropicalis
831326 Arabidopsis thaliana
5446993 Ajellomyces capsulatus NAm1
100135827 Oncorhynchus mykiss
100635510 Amphimedon queenslandica
12349 Mus musculus
54231 Rattus norvegicus
760 Homo sapiens
280740 Bos taurus
100009156 Oryctolagus cuniculus
100719293 Cavia porcellus
100154873 Sus scrofa
396257 Gallus gallus
101113341 Ovis aries
477928 Canis lupus familiaris
574263 Macaca mulatta
5717780 Chlamydomonas reinhardtii
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