Carbonyl Reductase 1 Proteins (CBR1)

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. Additionally we are shipping CBR1 Antibodies (121) and CBR1 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CBR1 873 P16152
CBR1 12408 P48758
CBR1 29224 P47727
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Top CBR1 Proteins at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 60 to 71 Days
$2,722.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human GST tag Carbonyl Reductase 1 (CBR1) (AA 2-277), (full length) protein (GST tag) 50 μg Log in to see 13 to 16 Days
$242.00
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 11 Days
$341.00
Details
Yeast Human His tag   50 μg Log in to see 8 to 11 Days
$341.00
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,722.50
Details

CBR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,
Mouse (Murine) ,
,
Rat (Rattus) ,
,

Top referenced CBR1 Proteins

  1. Human CBR1 Protein expressed in Wheat germ - ABIN1348184 : Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism. in Xenobiotica; the fate of foreign compounds in biological systems 2015 (PubMed)

More Proteins for Carbonyl Reductase 1 (CBR1) Interaction Partners

Human Carbonyl Reductase 1 (CBR1) interaction partners

  1. Data suggest that fatty acids and acyl-CoAs bind competitively with respect to substrate binding to carbonyl reductase 1 (CBR1), an enzyme involved in first-pass drug metabolism in intestinal mucosa; inhibition of CBR1 by these products of digestion may lead to food-drug interactions.

  2. AKR1C3 (show AKR1C3 Proteins) is the primary enzyme and CBR1 is a minor enzyme responsible for warfarin reduction in human liver cytosol.

  3. These results suggest that CR1 induces apoptosis by activating the caspase (show CASP3 Proteins) pathway via binding to TNFR1 (show TNFRSF1A Proteins).

  4. Critical insights into the substrate selectivity of hCBR1 and the interaction between hCBR1 and glutathione.

  5. Up-Regulation of Carbonyl Reductase 1 Renders Development of Doxorubicin Resistance in Human Gastrointestinal Cancers

  6. CBR1 decreases promoted tumor proliferation and growth as well as invasion and metastasis; CBR1 has potential to become a new candidate for molecular targeting therapy.

  7. Inhibition of CBR1 may increase the efficacy of daunorubicin in cancer tissue.

  8. Protein products of AKR1C1 (show DDH Proteins), AKR1C2 (show AKR1C2 Proteins), AKR7A3 (show AKR7A3 Proteins), CYP3A4 (show CYP3A4 Proteins), and carbonyl reductase (CBR1) were found in tumors and those of AKR1C1 (show DDH Proteins), AKR7A3 (show AKR7A3 Proteins), and CBR1 correlated with their transcript levels.

  9. we suggest that PEP-1-CBR1 protein may be a therapeutic agent for the treatment of ischemic injuries as well as oxidative-stress-induced (show SQSTM1 Proteins) cell damage and death.

  10. The stimulatory effect of cortisol on CBR1 expression may partly explain the concurrent increases of cortisol and prostaglandin PGF2alpha in human amnion tissue prior to the onset of labor

Pig (Porcine) Carbonyl Reductase 1 (CBR1) interaction partners

  1. two Cys residues, Cys 149 and Cys 226, are involved in the enzyme activity; Cys 226 is involved in binding of the cofactor NADPH.

Cow (Bovine) Carbonyl Reductase 1 (CBR1) interaction partners

  1. results indicate that the disturbances in 9-KPR activity in bovine retained placenta exist but their reasons still require further experiments

Mouse (Murine) Carbonyl Reductase 1 (CBR1) interaction partners

  1. CBR1 plays a critical role in controlling redox balance and detoxifying lipid peroxidation during muscle differentiation and regeneration.

  2. CBR1 attenuates apoptosis and promotes cell survival in pancreatic beta-cell lines under glucotoxic and glucolipotoxic conditions via reducing ROS (show ROS1 Proteins) generation

CBR1 Protein Profile

Protein Summary

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q.

Gene names and symbols associated with Carbonyl Reductase 1 Proteins (CBR1)

  • carbonyl reductase 1 (cbr1)
  • carbonyl reductase 1 (CBR1)
  • carbonyl reductase 1 (LOC100222525)
  • carbonyl reductase (Smp_033530.3)
  • carbonyl reductase 1 (Cbr1)
  • 9-KPR protein
  • AW261796 protein
  • Cbr protein
  • CR protein
  • hCBR1 protein
  • LOC100222525 protein
  • MGC131152 protein
  • SDR21C1 protein

Protein level used designations for Carbonyl Reductase 1 Proteins (CBR1)

carbonyl reductase [NADPH] 1 , carbonyl reductase 1 , 15-hydroxyprostaglandin dehydrogenase , 20-beta-hydroxysteroid dehydrogenase , NADPH-dependent carbonyl reductase 1 , prostaglandin 9-ketoreductase , prostaglandin-E(2) 9-reductase , carbonyl reductase , carbonyl reductase (NADPH) 1 , short chain dehydrogenase/reductase family 21C, member 1 , 20-hydroxysteroid dehydrogenase , prostaglandin E(2) 9-keto reductase , NADPH:secondary-alcohol oxidoreductase , Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1) , Cbr 1

GENE ID SPECIES
373866 Danio rerio
496612 Xenopus (Silurana) tropicalis
100172097 Pongo abelii
100222525 Taeniopygia guttata
734804 Xenopus laevis
8353921 Schistosoma mansoni
873 Homo sapiens
418512 Gallus gallus
610164 Canis lupus familiaris
397143 Sus scrofa
515946 Bos taurus
100009528 Oryctolagus cuniculus
12408 Mus musculus
29224 Rattus norvegicus
Selected quality suppliers for CBR1 Proteins (CBR1)
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