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Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. Additionally we are shipping CBR3 Antibodies (71) and CBR3 Kits (4) and many more products for this protein.
Showing 8 out of 14 products:
Human CBR3 Protein expressed in Escherichia coli (E. coli) - ABIN667118
Miura, Nishinaka, Terada: Importance of the substrate-binding loop region of human monomeric carbonyl reductases in catalysis and coenzyme binding. in Life sciences 2009
Show all 2 references for ABIN667118
Human CBR3 Protein expressed in Escherichia coli (E. coli) - ABIN2006310
Lakhman, Ghosh, Blanco: Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3). in Drug metabolism and disposition: the biological fate of chemicals 2005
Show all 2 references for ABIN2006310
Human CBR3 Protein expressed in Wheat germ - ABIN1348188
Bains, Karkling, Lubieniecka, Grigliatti, Reid, Riggs: Naturally occurring variants of human CBR3 alter anthracycline in vitro metabolism. in The Journal of pharmacology and experimental therapeutics 2010
association of SNPs in ABCB1 (show ABCB1 Proteins) and CBR3 with chronic cardiotoxicity in a cohort of breast cancer patients treated with anthracyclines.
Variants of CBR3 and GSTP1 (show GSTP1 Proteins) enzymes may be associated with changes in short-term functional cardiac parameters.
genetic polymorphism in the CBR3 gene conferred risk of type 2 diabetes and insulin (show INS Proteins) resistance in Chinese. The association was probably mediated through modulation of adipogenesis.
CBR3 polymorphisms contribute to increased cardiomyopathy risk associated with anthracycline treatment of childhood cancer.
CBR3 is a novel target gene of inflammatory stimuli; elucidation of its detailed role in inflammation deserves further investigation.
Computational searches identify a conserved antioxidant response element(ARE) in the distal carbonyl reductase 3 (CBR3) promoter region.
The CBR3 distal promoter contains an activating cis (show CISH Proteins)-regulatory element that is responsive to Trichostatin A (TSA (show PRDX2 Proteins)) treatment according to promoter reporter assays in HEK (show EPHA3 Proteins) 293 cells.
a physiological role of CBR1 (show CBR1 Proteins), but not for CBR3, in S-nitrosoglutathione reduction and thus ultimately in regulation of NO signaling
CBR3 is regulated via NRF2 (show GABPA Proteins)-dependent signaling pathways, a finding and plays an important role in the cellular response to oxidative stress.
analysis of the structural basis for substrate specificity in human monomeric carbonyl reductases CBR3
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.
carbonyl reductase 3
, NADPH-dependent carbonyl reductase 3
, carbonyl reductase (NADPH) 3
, carbonyl reductase [NADPH] 3
, short chain dehydrogenase/reductase family 21C, member 2