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The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. Additionally we are shipping Carbonyl Reductase 4 Antibodies (38) and Carbonyl Reductase 4 Kits (1) and many more products for this protein.
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Human CBR4 Protein expressed in Escherichia coli (E. coli) - ABIN667836
Chen, Kastaniotis, Miinalainen, Rajaram, Wierenga, Hiltunen: 17beta-hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009
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Human CBR4 Protein expressed in Wheat germ - ABIN1348190
Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism. in Xenobiotica; the fate of foreign compounds in biological systems 2015
Show all 2 references for ABIN1348190
CBR4 is a mitochondrial NADPH (show NQO1 Proteins)-dependent reductase for o- and p-quinones.
Hs17beta-HSD8 (show CCDC91 Proteins) and HsCBR4 show a strong genetic interaction in vivo in yeast, where, only if they are expressed together, they rescue the respiratory deficiency and restore the lipoic acid content of oar1Delta cells.
The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (By similarity).
carbonyl reductase 4
, carbonyl reductase family member 4
, quinone reductase CBR4
, 3-oxoacyl-[acyl-carrier-protein] reductase
, carbonic reductase 4
, short chain dehydrogenase/reductase family 45C, member 1