Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
CPA4 is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Additionally we are shipping Carboxypeptidase A4 Antibodies (15) and Carboxypeptidase A4 Kits (5) and many more products for this protein.
Showing 10 out of 13 products:
Human CPA4 Protein expressed in HEK-293 Cells - ABIN2180902
Huang, Reed, Zhang, Shridhar, Wang, Smith: Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells. in Cancer research 1999
Show all 3 references for ABIN2180902
Knockdown of cpa6 mRNA also reduced levels of mRNAs encoding neuropeptide precursors (bdnf, npy, chga, pcsk1nl, tac1, nts, edn1), a neuropeptide processing enzyme (cpe), transcription factor (c-fos), and molecules implicated in glutamatergic signaling
CPA4 functions in neuropeptide processing and regulation in the extracellular environment
The crystal structure of the human CPA4 carboxypeptidase in complex with SmCI, a peptide protease inhibitor.
NvCL form Nerita versicolor is a tight-binding inhibitor that interacts with the active site of the CPA4 in a substrate-like manner.
CPA4 gene is imprinted, with preferential expression from the maternal allele in many fetal tissues, but not in fetal brain.
The three-dimensional structure of procarboxypeptidase-A4 (hPCPA4) has been solved and shows the features of related metallocarboxypeptidase zymogens, with a preformed alpha/beta/-hydrolase active-enzyme moiety (hCPA4) and an inhibiting pro-domain (PD).
This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness.
, carboxypeptidase A4-like
, carboxypeptidase A3