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CEACAM3 encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. Additionally we are shipping CEACAM3 Proteins (10) and CEACAM3 Kits (6) and many more products for this protein.
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Human Monoclonal CEACAM3 Primary Antibody for IF (p), IHC (p) - ABIN722931
Yu, Zhan, Liu, Lv, Duan: Plasma-enhanced antibody immobilization for the development of a capillary-based carcinoembryonic antigen immunosensor using laser-induced fluorescence spectroscopy. in Analytical chemistry 2013
Show all 5 references for ABIN722931
Human Polyclonal CEACAM3 Primary Antibody for WB - ABIN611365
Cain, Brown, Langlais, Cohen: Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex. in The Journal of biological chemistry 1999
Show all 4 references for ABIN611365
Human Polyclonal CEACAM3 Primary Antibody for IHC (p), WB - ABIN657776
Ali, Kaye, Adamson, Tait, Polignano, Highley: CA 19-9 and survival in advanced and unresectable pancreatic adenocarcinoma and cholangiocarcinoma. in Journal of gastrointestinal cancer 2008
COLIV is a promising tumour marker for CLM and can possibly be used to detect postoperative CLM recurrence. The combination of COLIV and CEA is superior to either marker alone in detecting CLM
The higher expression of CD44v6, integrin-beta1, CA199, and CEA (show CEACAM5 Antibodies) are closely related to the progression and metastasis of pancreatic cancer.[CA199, CD44v6]
A failure of CEACAM3-mediated innate immune detection might be linked to the ability of gonococci to cause disseminated infections.
Grb14 (show GRB14 Antibodies) is the first negative regulator of CEACAM3-initiated bacterial phagocytosis and might help to focus granulocyte responses to the subcellular sites of pathogen-host cell contact
CEACAM3 promotes opsonin-independent phagocytosis of CEACAM-binding bacteria. CEACAM3 is the main driver for this process on human granulocytes.
The authors show that the expression of CEACAM1 (show CEACAM1 Antibodies) and CEACAM6 potentiate CEACAM3-dependent responses of neutrophils, exposing a cooperative role for this family of proteins during neisserial infection of neutrophils.
the prognostic value of preoperative serum carbohydrate antigen19-9, carcinoembryonic antigen (show CEACAM5 Antibodies), and carbohydrate antigen 125 for overall survival in patients with colorectal cancer was studied
the ability of CEACAM3 to coordinate signaling events that not only mediate bacterial uptake, but also trigger the killing of internalized pathogens.
CEACAM6 and a regulatory element near the 3' end of CEACAM3 are associated with cystic fibrosis (show S100A8 Antibodies) disease severity and intrapair discordance
CEACAM3 has a role in internalizing bacteria to epithelial cells
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.
, carcinoembryonic antigen CGM1
, carcinoembryonic antigen gene family member 1
, nonspecific cross-reacting antigen
, pregnancy-specific glycoprotein 24
, Carcinoembryonic antigen gene family (CGM1)
, Carcinoembryonic antigen gene family member 4 / (carcinoembryonic antigene-related protein)
, carcinoembryonic antigen gene family 4
, CEA-related cell adhesion molecule 12
, IGF-like family member 3-like
, carcinoembryonic antigen-related cell adhesion molecule 3