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Carcinoembryonic antigen (CEA\\\\; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma.
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Human Monoclonal CEACAM1/3/6 Primary Antibody for IHC (fro), FACS - ABIN2472302
NGuessan, Vigelahn, Bachmann, Zabel, Opitz, Schmeck, Hippenstiel, Zweigner, Riesbeck, Singer, Suttorp, Slevogt: The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells. in The Journal of infectious diseases 2007
a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO (show MPO Antibodies), CEACAM8, CRISP3 (show CRISP3 Antibodies), MS4A3 (show MS4A3 Antibodies), CEACAM6, HEMGN, and MMP8 (show MMP8 Antibodies)
In enterocytic C2BBe1 cells, Candida albicans caused a transient tyrosine phosphorylation of CEACAM1 (show CEACAM1 Antibodies) and induced higher expression of membrane-bound CEACAM1 (show CEACAM1 Antibodies) and soluble CEACAM6.
show the upregulation of the tumor-associated antigens CEACAM5 (show CEACAM5 Antibodies)/6 by trans-signaling of the pro-inflammatory cytokine IL-6 (show IL6 Antibodies)
Data suggest ways in which carcinoembryonic antigen-related cell adhesion molecules CEACAM6 and CEACAM8 regulate the biological functions of one another.
vaccination with recombinant attenuated Salmonella harboring the CEACAM6 and 4-1BBL (show TNFSF9 Antibodies) gene efficiently increased the number of CD3 (show CD3 Antibodies)+CD8 (show CD8A Antibodies)+ TIL (show TLR1 Antibodies) and NK cells, decreased the number of FOXP3 (show FOXP3 Antibodies) cells and inhibited the development of DMH (show DST Antibodies)-induced colorectal cancer
CEACAM6 increased the levels of phosphorylated AKT (show AKT1 Antibodies), which is involved in the progression of a variety of human tumors.
Data show that carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) and forkhead box P3 (FOXP3 (show FOXP3 Antibodies)) are associated with the malignant degree of pancreatic cancer.
Data indicate that carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes angiogenesis in gastric cancer via focal adhesion kinase FAK signaling.
Results show that pancreatic cancer patients with CEACAM 1 (show CEACAM1 Antibodies), 5 and 6 expression showed a significantly shortened overall survival and elevated serum values are correlated with distant metastasis suggesting a role in epithelial-mesenchymal transition.
CEACAM6 expression was expressed in different molecular subtypes of breast cancer. Among different subtypes, the highest expression was found with HER2 (show ERBB2 Antibodies) positive cancers.
Carcinoembryonic antigen (CEA\; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD form of CEA (Barnett et al., 1988
carcinoembryonic antigen-related cell adhesion molecule 6
, non-specific crossreacting antigen
, normal cross-reacting antigen