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CEACAM3 encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. Additionally we are shipping CEACAM3 Antibodies (61) and CEACAM3 Kits (3) and many more products for this protein.
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CEACAM3 signalling in neutrophils is able to specifically modulate airway inflammation caused by infection with M. catarrhalis.
We demonstrate that recombinant Neisseria Opa proteins reconstituted into liposomes retain the ability to recognize and interact with CEACAM1 (show CEACAM1 Proteins) and 3 in vitro but do not maintain receptor specificity compared to that of Opa proteins natively expressed by Neisseria gonorrhoeae.
Opacity protein OpaI of Neisseria gonorrhoeae in lipooligosaccharide mutants lost ability to interact with neutrophil-restricted CEACAM3.
p-CEA (show CEACAM5 Proteins) measurement in patients with pleural effusion of uncertain etiology is a safe and cost-effective procedure, everywhere easily available, which may help clinicians in selecting patients for further evaluations
Demonstrated the CEACAM3 specificity and a perioperative trend of circulating tumor cells which is coherent with the clinical/pathological considerations in colorectal cancer.
COLIV is a promising tumour marker for CLM and can possibly be used to detect postoperative CLM recurrence. The combination of COLIV and CEA is superior to either marker alone in detecting CLM
The higher expression of CD44v6, integrin-beta1, CA199, and CEA (show CEACAM5 Proteins) are closely related to the progression and metastasis of pancreatic cancer.[CA199, CD44v6]
A failure of CEACAM3-mediated innate immune detection might be linked to the ability of gonococci to cause disseminated infections.
Grb14 (show GRB14 Proteins) is the first negative regulator of CEACAM3-initiated bacterial phagocytosis and might help to focus granulocyte responses to the subcellular sites of pathogen-host cell contact
CEACAM3 promotes opsonin-independent phagocytosis of CEACAM-binding bacteria. CEACAM3 is the main driver for this process on human granulocytes.
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.
, carcinoembryonic antigen CGM1
, carcinoembryonic antigen gene family member 1
, nonspecific cross-reacting antigen
, pregnancy-specific glycoprotein 24
, Carcinoembryonic antigen gene family (CGM1)
, Carcinoembryonic antigen gene family member 4 / (carcinoembryonic antigene-related protein)
, carcinoembryonic antigen gene family 4
, CEA-related cell adhesion molecule 12
, IGF-like family member 3-like
, carcinoembryonic antigen-related cell adhesion molecule 3