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anti-Cardiac Troponin C (TNNC1) Antibodies

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Additionally we are shipping TNNC1 Proteins (14) and TNNC1 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNNC1 7134 P63316
TNNC1 290561  
TNNC1 21924 P19123
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Top anti-TNNC1 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-cardiac Troponin C antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Anti-TNNC1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104746 concentration 10 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated ELISA (Capture), ELISA, WB   1 mg Log in to see 4 to 5 Days
$417.92
Details
Human Mouse Un-conjugated ELISA, WB   1 mg Log in to see 4 to 5 Days
$417.92
Details
Human Mouse Un-conjugated ELISA (Detection), ELISA, WB   1 mg Log in to see 4 to 5 Days
$418.11
Details
Human Mouse Un-conjugated WB Western Blot analysis of TNNC1 expression in transfected 293T cell line by TNNC1 monoclonal antibody (M01), clone 1F8-A9. Lane 1: TNNC1 transfected lysate(18.4 KDa). Lane 2: Non-transfected lysate. Immunoperoxidase of monoclonal antibody to TNNC1 on formalin-fixed paraffin-embedded human heart (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details

TNNC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Rat (Rattus)
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Mouse (Murine)
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More Antibodies against TNNC1 Interaction Partners

Human Cardiac Troponin C (TNNC1) interaction partners

  1. We used nuclear magnetic resonance and circular dichroism to solve the structure and characterize the backbone dynamics and stability of the regulatory domain of cTnC with the L29Q mutation.

  2. conclusive evidence that TNNC1 is an uncommon but definitive HCM-susceptibility gene

  3. Troponin C (TnC) and the N-terminal helix of Troponin I (TnI N-helix), which occurs in vivo during muscle contraction.

  4. FAK (show PTK2 Antibodies)/CREB (show CREB1 Antibodies)/TNNC1 has a role in mediating the effect of stromal MFAP5 (show MFAP5 Antibodies) on ovarian cancer metastatic potential

  5. Mutations in cTnC have been associated with hypertrophic or dilated cardiomyopathy.[review]

  6. Data suggest that mutation A162H in switch region of troponin I induces transitory curved conformation and promotes contraction of troponin I bound to regulatory domain of troponin C; this is countered by residue E164 to ensure proper relaxation.

  7. in vitro characterisation of six cardiac Troponin C mutations causing hypertrophic and dilated cardiomyopathies (Review)

  8. The conformational dynamics of N-terminal lobe of TnC (show TNC Antibodies) plays an important role in the regulation of cardiac muscle contraction.

  9. Data indicate that domain positioning impacts the effective concentration of cardiac isoform of troponin I (cTnI) presented to cardiac troponin C (cTnC).

  10. Toponin I, T, and C play crucial roles in muscle activity, connecting changes in intracellular Ca2 (show CA2 Antibodies)+ concentration with generation of contraction. [review]

Cow (Bovine) Cardiac Troponin C (TNNC1) interaction partners

  1. These results demonstrate that the L29Q mutation enhances the Ca(2+)-binding characteristics of cTnC and that when incorporated into cardiac myocytes, this mutant alters myocyte contractility.

Mouse (Murine) Cardiac Troponin C (TNNC1) interaction partners

  1. Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle.

  2. A region in cTnC associated with increased Ca(2 (show CA2 Antibodies)+) sensitivity in skinned fibers was identified, an the F27W reporter mutation affected Ca(2 (show CA2 Antibodies)+) sensitivity, maximal force, and ATPase (show DNAH8 Antibodies) activation of some mutants.

  3. Overexpression of sTnC (show TNNC2 Antibodies) polypeptide in muscle cells is controlled by its rapid degradation.

  4. These results demonstrate that the L29Q mutation enhances the Ca(2+)-binding characteristics of cTnC and that when incorporated into cardiac myocytes, this mutant alters myocyte contractility.

TNNC1 Antigen Profile

Protein Summary

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase\; TnT, which contains the binding site for tropomyosin\; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Gene names and symbols associated with TNNC1

  • troponin C type 1 (slow) (tnnc1) antibody
  • cardiac troponin C (tnnc1) antibody
  • troponin C type 1 (slow) (TNNC1) antibody
  • troponin C type 1 (slow) (Tnnc1) antibody
  • troponin C, cardiac/slow skeletal (Tnnc1) antibody
  • troponin C, slow (LOC100347570) antibody
  • AI874626 antibody
  • CMD1Z antibody
  • CMH13 antibody
  • cTnC antibody
  • cTnI antibody
  • MGC80066 antibody
  • PCTNC1 antibody
  • TN-C antibody
  • TnC antibody
  • tncc antibody
  • TNNC antibody
  • TNNC1 antibody

Protein level used designations for TNNC1

cardiac troponin C , slow twitch skeletal/cardiac muscle troponin C , troponin C, slow skeletal and cardiac muscles , troponin C1, slow , troponin C, cardiac/slow skeletal , TN-C , Troponin C, slow skeletal and cardiac muscles

GENE ID SPECIES
379410 Xenopus laevis
399104 Xenopus laevis
7134 Homo sapiens
290561 Rattus norvegicus
396032 Gallus gallus
100156435 Sus scrofa
509486 Bos taurus
21924 Mus musculus
100347570 Oryctolagus cuniculus
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