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CNDP1 encodes a member of the M20 metalloprotease family. Additionally we are shipping Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) Kits (11) and Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) Proteins (10) and many more products for this protein.
Showing 10 out of 86 products:
Human Polyclonal CNDP1 Primary Antibody for EIA, FACS - ABIN951583
Craig, Millis, DiStefano: Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetes. in Diabetic medicine : a journal of the British Diabetic Association 2009
Show all 2 references for ABIN951583
Human Polyclonal CNDP1 Primary Antibody for ELISA - ABIN1995617
Riedl, Koeppel, Brinkkoetter, Sternik, Steinbeisser, Sauerhoefer, Janssen, van der Woude, Yard: A CTG polymorphism in the CNDP1 gene determines the secretion of serum carnosinase in Cos-7 transfected cells. in Diabetes 2007
CNDP1 and CARNS are expressed in glomeruli and tubular cells; TauT (show TAUT Antibodies) is expressed in renal epithelial cells; CDNP1 may have a role in diabetic neuropathy
Data shows that higher carnosine content in human skeletal muscle is positively associated with insulin (show INS Antibodies) resistance and fasting metabolic preference for glucose.
In gastrointestinal cancer, reduced plasma levels of CNDP1 associate with signs of catabolism and poor outcome.
Alterations of serum carnosinase (CN1) activity has been associated with several pathological conditions, such as neurological disorders, chronic diseases and cancer
Rs12604675-A in CNDP1 may confer susceptibility to overt proteinuria in Japanese women with type 2 diabetes.
In this review, correlations between serum carnosine and carnosinase activity and polymorphism in CNDP1 gene are analyzed. The role of CNDP1 gene polymorphism the development of diabetic nephropathy and non-diabetic chronic kidney disease is discussed.
Plasma levels of FLT (show FLT1 Antibodies) and S100A9 (show S100A9 Antibodies) proteins are up-regulated and CNDP1 levels are down-regulated in patients with glioblastoma.
Common variants in CNDP1 and CNDP2 (show CNDP2 Antibodies) play a role in susceptibility to kidney disease in patients with type 2 diabetes.
These findings provide nominal evidence supporting a role between CNDP1 variants and diabetic kidney disease.
neither CNDP1 genotype nor the normal variation in circulating testosterone levels affects the muscular carnosine content
This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region.
carnosine dipeptidase 1 (metallopeptidase M20 family)
, beta-Ala-His dipeptidase
, CNDP dipeptidase 1
, carnosinase 1
, glutamate carboxypeptidase-like protein 2
, serum carnosinase