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Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. Additionally we are shipping Casein Kinase 2, alpha 1 Polypeptide Proteins (21) and Casein Kinase 2, alpha 1 Polypeptide Kits (11) and many more products for this protein.
Showing 10 out of 137 products:
Human Polyclonal CSNK2A1 Primary Antibody for WB - ABIN1944742
Devilat, Carvallo: Structure and sequence of an intronless gene for human casein kinase II-alpha subunit. in FEBS letters 1993
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Human Polyclonal CSNK2A1 Primary Antibody for WB - ABIN1881717
Ahmed, Davis, Hanten, Lambert, McIvor, Goueli: Cloning of cDNAs encoding the alpha and beta subunits of rat casein kinase 2 (CK-2): investigation of molecular regulation of CK-2 by androgens in rat ventral prostate. in Cellular & molecular biology research 1994
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Human Polyclonal CSNK2A1 Primary Antibody for WB - ABIN1944758
Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003
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Human Monoclonal CSNK2A1 Primary Antibody for IF, PLA - ABIN514706
Lin, Hung, Lin, Li, Lee, Li, Chen, Chen, Yang: CK2 inhibitors enhance the radiosensitivity of human non-small cell lung cancer cells through inhibition of stat3 activation. in Cancer biotherapy & radiopharmaceuticals 2011
identify the the ZmeIF5A serine residues phosphorylated by CK2
analysis of free energy differences of binding of adenosine triphosphate (ATP) and guanine triphosphate (GTP (show AK3 Antibodies)) to the protein kinase CK2
The regulatory subunit of protein kinase CK2 is identified as a novel intracellular partner of AdipoR1 (show ADIPOR1 PLURAL_@2012@) and CK2 is shown to be an effector molecule in adiponectin (show ADIPOQ PLURAL_@2012@) signaling.
CK2alpha-4 is a splicing variant of maize protein kinase CK2, and may function as a negative regulator of other CK2s.
To clarify the control mechanism of the catalytic activity of casein kinase 2 (CK2) during early embryonic development in the silkworm, Bombyx mori, attempted an in-vitro functional analysis by using the recombinant alpha and beta subunits of B. mori CK2
data implicate CK2 as a regulator of the Th17/Treg axis and Th17 cell maturation and suggest that CK2 could be targeted for the treatment of Th17 cell-driven autoimmune disorders.
This study demonstrates that CSNK2A1 and SIRT6 (show SIRT6 Antibodies) are indicators of poor prognosis for breast carcinomas and that CSNK2A1-mediated phosphorylation of SIRT6 (show SIRT6 Antibodies) might be involved in the progression of breast carcinoma.
Our results disclose a novel interplay between ubiquitin- and phosphorylation-dependent signalling, and represent the first report of a regulatory mechanism for UIM-dependent function. They also suggest that CK2 inhibitors could release the full neuroprotective potential of HSJ1 (show DNAJB2 Antibodies), and deserve future interest as therapeutic strategies for neurodegenerative disease.
CK2 inhibition in monocyte-derived dendritic cells led to an enhanced Th2 polarization in the absence of contact sensitizer stimulation.
In the present work we have shown a key role for protein kinase CK2 in promoting LSC (show ARHGEF1 Antibodies) survival through the modulation of the STAT3 (show STAT3 Antibodies), NF-kappaB (show NFKB1 Antibodies) and AKT (show AKT1 Antibodies)/FOXO (show FOXO3 Antibodies) signaling pathways. We have also shown that CK2 inactivation makes LSCs more sensitive to the chemotherapeutic drug doxorubicin.
this study shows that breakpoint cluster region protein (show BCR Antibodies) regulates inflammation development via the alpha subunit of casein kinase II
our findings establish an important regulatory role of CK2alpha on BMI1 (show BMI1 Antibodies) phosphorylation and stability and implicate the CK2alpha/BMI1 (show BMI1 Antibodies) axis in ovarian cancer.
we identify a therapeutically exploitable posttranslational mechanism by which CK2alpha-mediated degradation of BRMS1 (show BRMS1 Antibodies) promotes metastases in lung cancer
The lack of intermediate species of CK2 alpha2beta2 in solution suggests that the holoenzyme is a strong/stable multimeric complex that does not spontaneously dissociate; a considerable amount of monomer, the active form of CK2, is present in low ionic strength solutions. Multimer assembly appears driven by electrostatic interactions between the CK2alpha P+1 loop and the CK2beta (show CSNK2B Antibodies) acidic loop.
These data support a role for casein kinase 2 in regulation of protein synthesis by downregulating stress granule formation through G3BP1 (show G3BP1 Antibodies).
CD5-CK2 signaling axis regulates positive selection by modulating activation of ERK and promoting survival independent of proximal TCR signals
This study shows for the first time that LPS (show TLR4 Antibodies) inhibits colonic biotin uptake via decreasing membrane expression of its transporter and that these effects likely involve a CK2-mediated pathway.
CK2.1 peptide drives chondrogenesis and cartilage formation without induction of chondrocyte hypertrophy by releasing CK2 from distinct sites at BMPRIa (show BMPR1A Antibodies)
showed that inhibition of CK2 greatly enhanced M3R (show CHRM3 Antibodies)-stimulated insulin (show INS Antibodies) secretion in human islets
Casein kinase 1 (show CSNK1A1 Antibodies) (alpha, delta and epsilon) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression.
CK2-regulated IQJC-SCHIP-1 association with AnkG (show ANK3 Antibodies) contributes to axon initial segment maintenance.
We suggest that L1 stimulates neuritogenesis by activating CK2alpha leading to decreased levels of PTEN (show PTEN Antibodies) and p53 (show TP53 Antibodies) via a novel, L1-triggered and CK2alpha-mediated signal transduction pathway.
our results identify CK2 as a novel regulator of TBK1 (show TBK1 Antibodies) and IRF3 (show IRF3 Antibodies) and suggest that targeting CK2 by small molecular inhibitor may be a viable approach to prevent and treat viral infections.
Cytokine-induced activation of NFkappaB in beta cells is dependent on CK2 activity, which phosphorylates NFkappaB p65 (show NFkBP65 Antibodies) at serine 529.
Involvement of ubiquitous protein kinase CK2 in angiogenesis. Naturally derived CK2 inhibitors may be useful for treatment of proliferative retinopathies. (Protein kinase CK2)
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.
CK II alpha 3
, CK2 catalytic subunit alpha
, casein kinase II alpha 1 polypeptide pseudogene
, casein kinase II alpha 1 subunit
, casein kinase II subunit alpha
, protein kinase CK2
, casein kinase 2 alpha subunit
, ck2 alpha
, casein kinase 2, alpha 1 polypeptide
, casein kinase 2 protein catalytic subunit
, casein kinase II subunit alpha-like
, CK II alpha
, casein kinase 2, alpha subunit
, CK II
, casein kinase II alpha subunit
, CK2 alpha subunit
, casein kinase2 subunit alpha
, casein protein kinase subunit alpha
, Casein kinase II alpha subunit
, casein kinase II, alpha 1 polypeptide
, casein kinase II, alpha 1 related sequence 4
, Casein kinase II subunit alpha'
, alpha subunit of casein kinase II