Casein Kinase 2, alpha 1 Polypeptide Proteins (CSNK2A1)

Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. Additionally we are shipping Casein Kinase 2, alpha 1 Polypeptide Antibodies (135) and Casein Kinase 2, alpha 1 Polypeptide Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CSNK2A1 100360989  
CSNK2A1 1457 P68400
CSNK2A1 12995 Q60737
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Top Casein Kinase 2, alpha 1 Polypeptide Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Mouse GST tag,His tag 50 μg Log in to see 20 to 21 Days
$338.80
Details
HOST_Baculovirus infected Insect Cells Human GST tag 50 μg Log in to see 20 to 21 Days
$338.80
Details
HOST_Baculovirus infected Insect Cells Human Un-conjugated 5 μg Log in to see 2 to 3 Days
$295.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$407.00
Details
HOST_Baculovirus infected Insect Cells Mouse Un-conjugated 50 μg Log in to see 20 to 21 Days
$338.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
$229.85
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details

CSNK2A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , , , , ,
, ,
Mouse (Murine) ,
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Top referenced Casein Kinase 2, alpha 1 Polypeptide Proteins

  1. Mouse (Murine) CSNK2A1 Protein expressed in Baculovirus infected Insect Cells - ABIN2008341 : Keller, Zeng, Wang, Zhang, Kapoor, Shu, Goodman, Lozano, Zhao, Lu: A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1. in Molecular cell 2001 (PubMed)
    Show all 3 references for 2008341

  2. Human CSNK2A1 Protein expressed in Baculovirus infected Insect Cells - ABIN2003163 : Boumann, de Kruijff, Heck, de Kroon: The selective utilization of substrates in vivo by the phosphatidylethanolamine and phosphatidylcholine biosynthetic enzymes Ept1p and Cpt1p in yeast. in FEBS letters 2004 (PubMed)
    Show all 3 references for 2003163

  3. Human CSNK2A1 Protein expressed in Escherichia coli (E. coli) - ABIN1098592 : Prudent, Moucadel, Nguyen, Barette, Schmidt, Florent, Lafanechère, Sautel, Duchemin-Pelletier, Spreux, Filhol, Reiser, Cochet: Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2. in Cancer research 2010 (PubMed)
    Show all 2 references for 1098592

More Proteins for Casein Kinase 2, alpha 1 Polypeptide (CSNK2A1) Interaction Partners

Maize/Corn (Zea mays) Casein Kinase 2, alpha 1 Polypeptide (CSNK2A1) interaction partners

  1. identify the the ZmeIF5A serine residues phosphorylated by CK2

  2. analysis of free energy differences of binding of adenosine triphosphate (ATP) and guanine triphosphate (GTP (show AK3 Proteins)) to the protein kinase CK2

  3. The regulatory subunit of protein kinase CK2 is identified as a novel intracellular partner of AdipoR1 (show ADIPOR1 Proteins) and CK2 is shown to be an effector molecule in adiponectin (show ADIPOQ Proteins) signaling.

  4. CK2alpha-4 is a splicing variant of maize protein kinase CK2, and may function as a negative regulator of other CK2s.

Silk Worm Casein Kinase 2, alpha 1 Polypeptide (CSNK2A1) interaction partners

  1. To clarify the control mechanism of the catalytic activity of casein kinase 2 (CK2) during early embryonic development in the silkworm, Bombyx mori, attempted an in-vitro functional analysis by using the recombinant alpha and beta subunits of B. mori CK2

Human Casein Kinase 2, alpha 1 Polypeptide (CSNK2A1) interaction partners

  1. data implicate CK2 as a regulator of the Th17/Treg axis and Th17 cell maturation and suggest that CK2 could be targeted for the treatment of Th17 cell-driven autoimmune disorders.

  2. This study demonstrates that CSNK2A1 and SIRT6 (show SIRT6 Proteins) are indicators of poor prognosis for breast carcinomas and that CSNK2A1-mediated phosphorylation of SIRT6 (show SIRT6 Proteins) might be involved in the progression of breast carcinoma.

  3. Our results disclose a novel interplay between ubiquitin- and phosphorylation-dependent signalling, and represent the first report of a regulatory mechanism for UIM-dependent function. They also suggest that CK2 inhibitors could release the full neuroprotective potential of HSJ1 (show DNAJB2 Proteins), and deserve future interest as therapeutic strategies for neurodegenerative disease.

  4. CK2 inhibition in monocyte-derived dendritic cells led to an enhanced Th2 polarization in the absence of contact sensitizer stimulation.

  5. In the present work we have shown a key role for protein kinase CK2 in promoting LSC (show ARHGEF1 Proteins) survival through the modulation of the STAT3 (show STAT3 Proteins), NF-kappaB (show NFKB1 Proteins) and AKT (show AKT1 Proteins)/FOXO (show FOXO3 Proteins) signaling pathways. We have also shown that CK2 inactivation makes LSCs more sensitive to the chemotherapeutic drug doxorubicin.

  6. this study shows that breakpoint cluster region protein (show BCR Proteins) regulates inflammation development via the alpha subunit of casein kinase II

  7. our findings establish an important regulatory role of CK2alpha on BMI1 (show BMI1 Proteins) phosphorylation and stability and implicate the CK2alpha/BMI1 (show BMI1 Proteins) axis in ovarian cancer.

  8. we identify a therapeutically exploitable posttranslational mechanism by which CK2alpha-mediated degradation of BRMS1 (show BRMS1 Proteins) promotes metastases in lung cancer

  9. The lack of intermediate species of CK2 alpha2beta2 in solution suggests that the holoenzyme is a strong/stable multimeric complex that does not spontaneously dissociate; a considerable amount of monomer, the active form of CK2, is present in low ionic strength solutions. Multimer assembly appears driven by electrostatic interactions between the CK2alpha P+1 loop and the CK2beta (show CSNK2B Proteins) acidic loop.

  10. These data support a role for casein kinase 2 in regulation of protein synthesis by downregulating stress granule formation through G3BP1 (show G3BP1 Proteins).

Mouse (Murine) Casein Kinase 2, alpha 1 Polypeptide (CSNK2A1) interaction partners

  1. data implicate CK2 as a regulator of the Th17/Treg axis and Th17 cell maturation and suggest that CK2 could be targeted for the treatment of Th17 cell-driven autoimmune disorders.

  2. CD5-CK2 signaling axis regulates positive selection by modulating activation of ERK and promoting survival independent of proximal TCR signals

  3. This study shows for the first time that LPS (show TLR4 Proteins) inhibits colonic biotin uptake via decreasing membrane expression of its transporter and that these effects likely involve a CK2-mediated pathway.

  4. CK2.1 peptide drives chondrogenesis and cartilage formation without induction of chondrocyte hypertrophy by releasing CK2 from distinct sites at BMPRIa (show BMPR1A Proteins)

  5. showed that inhibition of CK2 greatly enhanced M3R (show CHRM3 Proteins)-stimulated insulin (show INS Proteins) secretion in human islets

  6. Casein kinase 1 (show CSNK1A1 Proteins) (alpha, delta and epsilon) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression.

  7. CK2-regulated IQJC-SCHIP-1 association with AnkG contributes to axon initial segment maintenance.

  8. We suggest that L1 stimulates neuritogenesis by activating CK2alpha leading to decreased levels of PTEN and p53 (show TP53 Proteins) via a novel, L1-triggered and CK2alpha-mediated signal transduction pathway.

  9. our results identify CK2 as a novel regulator of TBK1 (show TBK1 Proteins) and IRF3 (show IRF3 Proteins) and suggest that targeting CK2 by small molecular inhibitor may be a viable approach to prevent and treat viral infections.

  10. Cytokine-induced activation of NFkappaB in beta cells is dependent on CK2 activity, which phosphorylates NFkappaB p65 (show NFkBP65 Proteins) at serine 529.

Cow (Bovine) Casein Kinase 2, alpha 1 Polypeptide (CSNK2A1) interaction partners

  1. Involvement of ubiquitous protein kinase CK2 in angiogenesis. Naturally derived CK2 inhibitors may be useful for treatment of proliferative retinopathies. (Protein kinase CK2)

Casein Kinase 2, alpha 1 Polypeptide (CSNK2A1) Protein Profile

Protein Summary

Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.

Gene names and symbols associated with CSNK2A1

  • casein kinase 2, alpha 1 polypeptide (CSNK2A1)
  • casein kinase 2, alpha 1 polypeptide (csnk2a1)
  • casein kinase 2 alpha subunit (CK2A)
  • CK2 protein kinase alpha 2 (cka2)
  • casein kinase 2 alpha subunit (Ck2a)
  • casein kinase II alpha subunit (Ckiialpha)
  • casein kinase 2, alpha 1 polypeptide (LOC100360989)
  • Casein kinase II alpha subunit (CK2A1)
  • casein kinase 1, alpha 1 (CSNK1A1)
  • casein kinase 2, alpha 1 polypeptide (Csnk2a1)
  • casein kinase 2, alpha prime polypeptide (CSNK2A2)
  • casein kinase 2, alpha prime polypeptide (Csnk2a2)
  • 1110035J23Rik protein
  • BmCK2a protein
  • C77789 protein
  • CK-II protein
  • CK2 protein
  • Ck2a protein
  • ck2a1 protein
  • CK2A2 protein
  • CKII protein
  • Ckiialpha protein
  • csnk2a1 protein
  • Csnk2a1-rs4 protein
  • CSNK2A3 protein

Protein level used designations for CSNK2A1

casein kinase 2, alpha 1 polypeptide , casein kinase II subunit alpha , casein kinase 2 protein catalytic subunit , casein kinase II subunit alpha-like , casein kinase 2 alpha subunit , CK2 alpha subunit , PCO082342 , PCO082342_ov , casein kinase II alpha subunit , casein kinase2 subunit alpha , casein protein kinase subunit alpha , ck2a2 , Casein kinase II alpha subunit , CK II alpha , casein kinase 2, alpha subunit , CK II , casein kinase II, alpha 1 polypeptide , CK II alpha 3 , CK2 catalytic subunit alpha , casein kinase II alpha 1 polypeptide pseudogene , casein kinase II alpha 1 subunit , protein kinase CK2 , casein kinase II, alpha 1 related sequence 4 , Casein kinase II subunit alpha' , alpha subunit of casein kinase II , CK II alpha' , casein kinase II subunit alpha' , casein kinase II, alpha 2, polypeptide

GENE ID SPECIES
477185 Canis lupus familiaris
100173187 Pongo abelii
100303588 Saccoglossus kowalevskii
100414021 Callithrix jacchus
445749 Ciona intestinalis
542460 Zea mays
692502 Bombyx mori
100121624 Nasonia vitripennis
100360989 Rattus norvegicus
100602220 Nomascus leucogenys
2898437 Paramecium tetraurelia strain d4-2
100301533 Oryctolagus cuniculus
432370 Gallus gallus
116549 Rattus norvegicus
1457 Homo sapiens
12995 Mus musculus
282419 Bos taurus
399319 Xenopus laevis
1459 Homo sapiens
13000 Mus musculus
282420 Bos taurus
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