You are viewing an incomplete version of our website. Please click to reload the website as full version.

Caspase 14, Apoptosis-Related Cysteine Peptidase Proteins (CASP14)

CASP14 encodes a member of the cysteine-aspartic acid protease (caspase) family. Additionally we are shipping Caspase 14, Apoptosis-Related Cysteine Peptidase Antibodies (85) and Caspase 14, Apoptosis-Related Cysteine Peptidase Kits (45) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CASP14 12365 O89094
Rat CASP14 CASP14 299587  
CASP14 23581 P31944
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Caspase 14, Apoptosis-Related Cysteine Peptidase Proteins at antibodies-online.com

Showing 7 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$841.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details

CASP14 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Human ,
,

Top referenced Caspase 14, Apoptosis-Related Cysteine Peptidase Proteins

  1. Human CASP14 Protein expressed in Escherichia coli (E. coli) - ABIN2004852 : Lippens, Kockx, Knaapen, Mortier, Polakowska, Verheyen, Garmyn, Zwijsen, Formstecher, Huylebroeck, Vandenabeele, Declercq: Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing. in Cell death and differentiation 2001 (PubMed)
    Show all 3 references for ABIN2004852

More Proteins for Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) Interaction Partners

Mouse (Murine) Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) interaction partners

  1. Mesotrypsin (show PRSS3 Proteins) generated saposins A-D from prosaposin (show PSAP Proteins), and mature caspase-14 contributed to this process by activating mesotrypsinogen (show PRSS3 Proteins) to mesotrypsin (show PRSS3 Proteins). Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  2. caspase-14 overexpression is not the cause of utricle formation

  3. Caspase-14-deficient mice are more prone to the development of parakeratosis.

  4. Mere impairment of filaggrin (show FLG Proteins) degradation by loss of caspase 14 does not influence the inflammatory threshold of atopic dermatitis.

  5. Caspase-14 is required for filaggrin (show FLG Proteins) degradation to natural moisturizing factors in the skin.

  6. Transcript profiling studies identified caspase (show GATA3 Proteins)-14 as a novel downstream target of Gata-3, in keeping with its roles in differentiation (show GATA3 Proteins) and tumorigenesis.

  7. We investigated whether cardiac autonomic control is impaired during sleep in ob/ob mice with morbid obesity caused by congenital leptin (show LEP Proteins) deficiency.

  8. processing of caspase 14 in epidermal differentiation

  9. SH2-B (show SH2B1 Proteins) dramatically enhanced leptin (show LEP Proteins)-stimulated tyrosine phosphorylation of IRS1 (show IRS1 Proteins) and IRS2 (show IRS2 Proteins) in human and mouse cells (this is supposed to be a NEWENTRY for mice--SH2-B (show SH2B1 Proteins)).

  10. Caspase-14, but not caspase-3 (show CASP3 Proteins) activation coincides temporally and spatially with embryonic KC differentiation, suggesting a role for caspase-14 in terminally differentiated KC.

Human Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) interaction partners

  1. overexpression of S100A7 (show S100A7 Proteins) in A431 skin squamous carcinoma cells significantly promoted cell proliferation in vitro and tumor growth in vivo, whereas it suppressed the expression of GATA-3 (show GATA3 Proteins) and caspase-14

  2. caspase-14 contributes to retinal pigment epithelium cell barrier disruption under hyperglycemic conditions.

  3. Caspase-14 was decreased in inflammatory lesions compared to non-lesion in atopic dermatitis. The amount of caspase-14 in the lesions correlated with clinical severity as determined by eczema area and severity index score and the skin barrier functions.

  4. Mesotrypsin (show PRSS3 Proteins) generated saposins A-D from prosaposin (show PSAP Proteins), and mature caspase-14 contributed to this process by activating mesotrypsinogen (show PRSS3 Proteins) to mesotrypsin (show PRSS3 Proteins). Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  5. partial loss of caspase 14 is not associated with dedifferentiation in neoplastic lesions of the oral mucosa

  6. genetic polymorphisms in AICDA (show AICDA Proteins) and CASP14 are associated with risk for brain tumor in Korean children.

  7. Suggest caspase-14 is a marker of human skin differentiation during development.

  8. Results suggest that caspase-14 may interact with GCM1 (show GCM1 Proteins) to participate in syncytiotrophoblast differentiation during placental development.

  9. ceramides, an important structural lipid, stimulate caspase-14 expression, coordinating formation of lipid lamellar membranes with the formation of corneocytes

  10. Caspase-14 might play a significant role in the pathogenesis of diabetic retinopathy by accelerating retinal endothelial and epithelial cells death.

Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) Protein Profile

Protein Summary

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Gene names and symbols associated with CASP14

  • caspase 14 (CASP14)
  • caspase 14 (Casp14)
  • caspase 14 (LOC100101622)
  • caspase 14, apoptosis-related cysteine peptidase (CASP14)
  • caspase 14, apoptosis-related cysteine peptidase (Casp14)
  • caspase-14-like (LOC485601)
  • caspase-15 (LOC780455)
  • CASP14 protein
  • MICE protein
  • mini-ICE protein

Protein level used designations for CASP14

caspase 14 , CASP-14 , caspase-14 , apoptosis-related cysteine protease , caspase 14, apoptosis-related cysteine protease

GENE ID SPECIES
100012133 Monodelphis domestica
12365 Mus musculus
299587 Rattus norvegicus
100101622 Oryctolagus cuniculus
23581 Homo sapiens
100715745 Cavia porcellus
517658 Bos taurus
485601 Canis lupus familiaris
780455 Ovis aries
Selected quality suppliers for Caspase 14, Apoptosis-Related Cysteine Peptidase Proteins (CASP14)
Did you look for something else?