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Caspase Recruitment Domain Family, Member 14 Proteins (CARD14)

CARD14 encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Additionally we are shipping CARD14 Antibodies (49) and CARD14 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CARD14 79092 Q9BXL6
CARD14 170720 Q99KF0
Rat CARD14 CARD14 688292  
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Top CARD14 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CARD14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Caspase Recruitment Domain Family, Member 14 (CARD14) Interaction Partners

Human Caspase Recruitment Domain Family, Member 14 (CARD14) interaction partners

  1. Genetic interactions of SNPs in CARD14, SENP1 (show SENP1 Proteins) and VEGFA (show VEGFA Proteins) might represent a functional mechanism in the pathogenesis of high altitude polycythemia.

  2. analysis of 105 individuals with generalized pustular psoriasis (GPP) identified a low-frequency variant (p.Asp176His) that causes constitutive CARD14 oligomerization

  3. CARD14 protein missense mutation found in patients diagnosed with psoriasis.

  4. no definite causative genetic mutation in CARD14 as identified in familial pityriasis rubra pilaris after screening 8 non-familial patients of type I, type III and type IV pityriasis rubra pilaris

  5. The study identified the DEP domain-containing protein DEPDC7 as cellular binding partner of CARMA2 and CARMA3 (show CARD10 Proteins) proteins.

  6. CARD14 mutation maybe responsible for activation of NF-kB signaling pathway in patients with pityriasis rubra pilaris.

  7. Transfection of dermal ECs with psoriasis-associated CARD14 mutations resulted in increased expression of several chemokines, including CXCL10 (show CXCL10 Proteins), IL-8 (show IL8 Proteins), and CCL2 (show CCL2 Proteins).

  8. Variant analysis of CARD14 in a Chinese Han population with psoriasis vulgaris and generalized pustular psoriasis shows that CARD14 may play a role in the pathogenesis of generalized pustular psoriasis.

  9. Owing to the relatively small number of cases analysed in this study, we cannot rule out the possibility that CARD14 mutations may be an exceptional cause of sporadic pityriasis rubra pilaris, as previously found in sporadic psoriasis

  10. CARD14 c.526G>C (p.Asp176His) may have a role in generalized pustular psoriasis with psoriasis vulgaris in Japanese patients

CARD14 Protein Profile

Protein Summary

This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with CARD14

  • caspase recruitment domain family, member 14 (CARD14)
  • caspase recruitment domain family, member 14 (Card14)
  • Bimp2 protein
  • CARMA2 protein
  • PRP protein
  • PSORS2 protein
  • PSS1 protein

Protein level used designations for CARD14

CARD-containing MAGUK protein 2 , bcl10-interacting maguk protein 2 , card-maguk protein 2 , carma 2 , caspase recruitment domain-containing protein 14 , bcl10-interacting MAGUK protein 2

GENE ID SPECIES
79092 Homo sapiens
170720 Mus musculus
688292 Rattus norvegicus
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