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Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Additionally we are shipping Caspase Recruitment Domain-Containing Protein 18 (ICEBERG) Antibodies (12) and many more products for this protein.
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Human CARD18 Protein expressed in Escherichia coli (E. coli) - ABIN1098230
Humke, Shriver, Starovasnik, Fairbrother, Dixit: ICEBERG: a novel inhibitor of interleukin-1beta generation. in Cell 2000
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CARD18 expression differs in healthy and psoriatic skin; moreover, CARD18 demonstrated altered response under inflammatory conditions in healthy and psoriatic skin
CARD18 may be both a promising marker for prognosis and a target protein for treatment of gastric cancer.
Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.
ICEBERG caspase-1 inhibitor
, caspase recruitment domain-containing protein 18
, caspase-1 inhibitor Iceberg