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CAT encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Additionally we are shipping Catalase Antibodies (247) and Catalase Proteins (26) and many more products for this protein.
Showing 10 out of 34 products:
Hadzi-Petrushev, Jankulovski, Hristov, Mladenov: L-2-oxothiazolidine-4-carboxylate influence on age- and heat exposure-dependent redox changes in rat's blood plasma. in The journal of physiological sciences : JPS 2011
Show all 5 references for ABIN1000296
Pastori, Pignatelli, Farcomeni, Menichelli, Nocella, Carnevale, Violi: Aging-Related Decline of Glutathione Peroxidase 3 and Risk of Cardiovascular Events in Patients With Atrial Fibrillation. in Journal of the American Heart Association 2016
Show all 4 references for ABIN2815076
Mouse (Murine) Catalase ELISA Kit for Sandwich ELISA - ABIN578280
Lv, Deng, Yu, Wang, Gong, Jia, Wang: Nrf2-ARE signals mediated the anti-oxidative action of electroacupuncture in an MPTP mouse model of Parkinson's disease. in Free radical research 2015
Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity.
Transcriptional activation of catalase by the DNA replication-related element (DRE)/DRE (show SUFUH ELISA Kits)- binding factor (DREF) system.
maintaining higher CAT and POD activities might be one of the reasons that the disruption of AtWNK8 enhances the tolerance to salt stress.
CAT1 (show SLC7A1 ELISA Kits) has a role in the resistance to the hemibiotrophic bacterial pathogen Pseudomonas syringae via a constitutively activated salicylic acid (SA) pathway.
CAT2 and NCA1 promote autophagy-dependent cell death in Arabidopsis.
The hyponastic leaves of cat2-1 reveal crosstalk between H2 O2 and auxin signalling that is mediated by changes in glutathione redox status.
NADP-ME2 (show NAD-ME ELISA Kits) transcripts accumulated in response to ozone or in mutants undergoing intracellular oxidative stress. Loss of NADP-ME2 (show NAD-ME ELISA Kits) function had little effect on cat2-triggered changes in glutathione or NADPH (show NQO1 ELISA Kits).
Introducing the cad2 (show CDX1 ELISA Kits) mutation into cat2 shows that the cad2 (show CDX1 ELISA Kits) mutation overrode the main features of the cat2 effect on thiol profiles.
Data indicate that in three different configurations, primary silencing signals were able to direct in trans methylation of chimeric transgenes and the CATALASE2 (CAT2) endogene.
the roles of catalase (CAT) in abscisic acid (ABA)-induced stomatal closure
Studies indicate that in apx1/cat2 double-mutant plants, a DNA damage response is activated, suppressing growth via a WEE1 kinase (show WEE1 ELISA Kits)-dependent cell-cycle checkpoint.
G-Box Binding Factor1 (GBF1 (show GBF1 ELISA Kits)) was identified as a DNA-binding protein (show CNBP ELISA Kits) of the CAT2 promoter.
The results obtained in this work suggest that variations of H(2)O(2) and catalase expression in Bombyx eggs are involved in diapause initiation and termination
Data show that liver catalase is able to tolerate very high levels of the modifying alpha-oxoaldehyde methylglyoxal so that its essential enzymatic function is not impaired.
The structure of bovine liver catalase determined from a single crystal at 3.2 A resolution by MicroED, is reported.
These maps demonstrate that it is indeed possible to build atomic models from such crystals and even to determine the charged states of amino acid residues in the Ca(2 (show CA2 ELISA Kits)+)-binding sites of Ca(2+)-ATPase (show CA-P60A ELISA Kits) and that of the iron atom in the heme in catalase.
Data indicate compatible osmolytes, proline, xylitol, and valine destabilize the denatured form of the catalase enzyme and, therefore, increase its disaggregation and thermal stability.
Flavonoid inhibition of catalase activity is, at least partially, due to the formation of hydrogen bonds between catalase and the flavonoid.
Comparison of deoxyferrous and oxyferrous complexes of cAOS and MAP with bovine liver catalase elucidates unresolved mechanistic questions in the catalytic cycles of these enzymes
Catalase is not influenced by the solvent during the catalytic reaction, which represents a lower energy barrier to be crossed in the overall energetics of the reaction, a fact that contributes to the high turnover rate of catalase.
At room temperature (25.0 degrees C) and higher, the addition of high concentrations of polymer is found to significantly enhance the affinity of SOD for catalase.
The high activity of catalase is not only determined by its distal environment but also by its partial ferryl character.
study of bovine liver catalase and [14C]NADPH (show FDXR ELISA Kits) and [14C]NADH revealed that unbound NADPH (show FDXR ELISA Kits) or NADH are substrates for an internal reductase and transhydrogenase reaction respectively
The purpose of the study was to evaluate the plasma level of superoxide dismutase (SOD (show SOD1 ELISA Kits)), catalase (CAT), and glutathione peroxidase (GPX (show GPX1 ELISA Kits)) and the association between polymorphic variants in genes encoding for GPx1 (show GPX1 ELISA Kits), SOD (show SOD1 ELISA Kits), CAT and the risk of distal symmetric polyneuropathy in type 2 diabetes mellitus patients.
This study indicates that catalase C-262T polymorphism is associated with the endometriosis.
Our results suggest that 389C>T may not contribute to vitiligo (show MITF ELISA Kits) susceptibility.
Increasing the endogenous NO level causes catalase inactivation and reactivation of intercellular apoptosis signaling specifically in tumor cells.
In patients with chronic hepatitis C, the GPX1 (show GPX1 ELISA Kits) Pro198Leu polymorphism, alone or combined with the CAT C-262T, was associated with high risk of fibrosis severity and hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)). In addition, GPX1 (show GPX1 ELISA Kits) polymorphism was also associated with advanced stages of HCC (show FAM126A ELISA Kits).
Deciphering the molecular mechanisms that regulate catalase expression could, therefore, be of crucial importance for the future development of pro-oxidant cancer chemotherapy.
Study shows that the SOD2 (show SOD2 ELISA Kits) 16C/T and CAT -21A/T alleles may serve as useful genetic susceptibility markers for migraine
the ratios SOD2 (show SOD2 ELISA Kits)/catalase and SOD2 (show SOD2 ELISA Kits)/Gpx1 (show GPX1 ELISA Kits) could be considered as potential markers during progression from tumor growth to metastasis
no significant correlations found between fertility and semen catalase activity
Functional roles of catalase, PRDX2 (show PRDX2 ELISA Kits) and GPX1 (show GPX1 ELISA Kits) during oxidative stress in human erythrocytes.
catalase protects mouse hearts against diabetic cardiomyopathy, partially by suppressing NF-kappaB (show NFKB1 ELISA Kits)-dependent inflammatory responses and associated protein nitration.
Hypoxia-generated red blood cells have low catalase and are preferentially destroyed.
The study shows how maturation of active catalase can be influenced by nitric oxide, S-nitrosylated GAPDH (show GAPDH ELISA Kits), and thioredoxin-1 (show TXN ELISA Kits), and how maturation may become compromised in inflammatory conditions such as asthma.
Data suggest that embryonic catalase is a determinant of risk for EtOH embryopathies.
exposure to either 14- or 28-day chronic stress resulted in a depressive-like syndrome, behavioural invigoration and aggression, and decreased activity of two major brain peroxidation enzymes, superoxide dismutase (show SOD1 ELISA Kits) and catalase.
The antioxidant catalase counteracts against high fat diet-induced cardiac geometric and functional anomalies possibly via an IKKbeta (show IKBKB ELISA Kits)-AMPK (show PRKAA1 ELISA Kits)-dependent restoration of myocardial autophagy.
The SirT1 (show SIRT1 ELISA Kits) regulates the expression of several antioxidant genes in bovine aortic endothelial cells, including Mn superoxide dismutase (show SOD2 ELISA Kits), catalase, peroxiredoxins 3 and 5, thioredoxin 2 (show TXN2 ELISA Kits), thioredoxin reductase 2 (show TXNRD2 ELISA Kits), and uncoupling protein 2 (show UCP2 ELISA Kits).
The levels of protein carbonyls, reactive oxygen species, and catalase in the cerebral hemispheres of young and aged mice, were evaluated.
The expression levels of catalase and SOD2 (show SOD2 ELISA Kits) are decreased in astrocytes when SIRT1 (show SIRT1 ELISA Kits) is inhibited.
Data indicate that transgenic mice over-expressing human SOD1 (show SOD1 ELISA Kits) or catalase were protected from loss of plasma membrane integrity (LPMI) at early but not late periods of reperfusion.
Antioxidants diphenyliodonium and N-acetylcysteine or overexpression of zebrafish catalase in GF-1 (show SOS1 ELISA Kits) cells also reduced ROS (show ROS1 ELISA Kits) production and protected cells for enhancing host survival rate due to red-spotted grouper nervous necrosis virus infection.
Effect of beta-naphthoflavone on catalase in various brain regions of pig is reported.
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
, cytosolic catalase
, CaTaLase family member (ctl-3)
, catalase 1